Identification and characterization of the powdery mildew resistance in cultivated emmer wheat accession Lxd-682 via bulked segregant RNA sequencing by Jiatong Li, Ningning Yu, Nina Sun, Lige Geng, Yanmin Qie, Dongfeng Zhai, Yuxiang Wang, Linzhi Li, Xueqing Liu, Xusheng Sun, Jiangchun Wang, Ruishan Liu, Guantong Pan, Shengmao Zou, Guohao Han, Yuli Jin, Pengtao Ma

“…Molecular markers JS717/JS718 and WGRC1096 were confirmed to be available for marker-assisted selection (MAS) of PmLxd-682 in breeding practices. …”
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Data‐Driven Theoretical Modeling of Centrifugal Step Emulsification and Its Application in Comprehensive Multiscale Analysis by Xin Wang, Xiaolu Cai, Chao Wan, Huijuan Yuan, Shunji Li, Yiwei Zhang, Ran Zhao, Yuxi Qin, Yiwei Li, Bi‐Feng Liu, Peng Chen

“…This predictive model empowers the CASE to achieve all‐in‐one functionality, including droplet pre‐design, generation, manipulation, and on‐site detection. …”
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BDNF Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults by Claire J. Cadwallader, Anna M. VandeBunte, D. Luke Fischer, Coty Chen, Valentina E. Diaz, Shannon Y. Lee, Brandon Chan, Argentina Lario‐Lago, Julio C. Rojas, Eliana Marisa Ramos, Jessica E. Rexach, Jennifer S. Yokoyama, Joel H. Kramer, Emily W. Paolillo, Rowan Saloner, Kaitlin B. Casaletto

“…In moderated mediation analyses examining cognitive outcomes, plasma p‐tau181 selectively mediated the relationship between PA and executive function in Val/Val participants. …”
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Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area by Wang YI, Longjun LIANG, Lichong YAN, Zhihua YAN, Jie CHEN, Wei GAO, Yi LOU, Fuqin YANG, Haiyang HU, Jiawei ZHU

“…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
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Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility by Jiao Gong, Huiru Sun, Kaiyuan Wang, Yanhui Zhao, Yechao Huang, Qinsheng Chen, Hui Qiao, Yang Gao, Jialin Zhao, Yunchao Ling, Ruifang Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Sijia Wang, Jiucun Wang, Guoqing Zhang, Shuhua Xu, Feng Qian, Fang Zhou, Huiru Tang, Dali Li, Chinese Pangenome Consortium (CPC), Fritz J. Sedlazeck, Li Jin, Yuting Guan, Shaohua Fan

“…Abstract Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. …”
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Evaluating Factors Affecting Interior Architectural Space Quality to Enhance Spatial Resilience and Human Productivity: An Application of Maslow’s Hierarchy of Needs by Moharam Ghahremani Drvish, Farhang Mozafar, Ceyed bagher Hoseini, Fateme Mahdizadeye seraj

“…</p> <p style="text-align: left;"><strong>Methodology.3</strong></p> <p style="text-align: left;">In the present study, the data and information was collected through document analysis, in-depth semi-structured interviews and formation of a focus group. The sample selection was done using snowball sampling method. …”
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

“…Introduction Understanding the genomic features of livestock is essential for successful breeding programs and conservation. Artificial selection is one of the major forces modifying the genetic composition of livestock populations. …”
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Insight into Antiviral Activity of Ag/TiO2 Nanocomposites Against Influenza H1N1 Virus and Its Antiviral Mechanism by Ma Y, Xiao X, Wang Y, Sun J, Tang P, Li J, Sun X, Xu D, Yang Z, Chen S, Liu X

“…The antiviral activities and the antiviral mechanism of ATA were investigated in detail by light microscopy, transmission electron microscopy and biological techniques such as cell cytotoxicity, 50% tissue culture infectious dose detection, western blot and reverse transcription-polymerase chain reaction.Results: These results showed the successful synthesis of ATA nanocomposite with uniform particle size and distribution. …”
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Comparative analysis of microwave indices for freeze/thaw state monitoring and adaptive thresholding implications by Zhicheng Yang, Tianjie Zhao, Qingfeng Wang, Lihua Peng, Youhua Ran, Yu Bai, Jingyao Zheng, Panpan Yao, Zhiqing Peng, Jinbiao Zhu, Xiaokang Kou, Yuei-An Liou, Jiancheng Shi

“…Near-surface soil freeze-thaw (F/T) cycles constitute a critical interface process regulating global hydrological dynamics, ecosystem succession, and climate feedback mechanisms. Leveraging its all-weather penetration capability, passive microwave remote sensing has emerged as a cornerstone for large-scale F/T state monitoring. …”
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Identification and characterization of the elusive protein backbone of the immuno-dominant and species-specific Em2(G11) metacestode antigen of Echinococcus multilocularis by Philipp A. Kronenberg, Philipp A. Kronenberg, Teivi Laurimäe, Teivi Laurimäe, Michael Reinehr, Michael Reinehr, Ansgar Deibel, Sina Hasler, Peter Gehrig, Achim Weber, Peter Deplazes, Peter Deplazes, Ramon M. Eichenberger, Ramon M. Eichenberger

“…NCBI BLAST revealed no other known protein homologues in related Echinococcus species nor helminths. After successfully producing this protein recombinantly (Em2rec), a monoclonal antibody (mAbEm2rec) was raised against it. …”
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Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review by Ukachukwu O Abaraogu, Philippa Dall, Chris Seenan, Sarah Rhodes, Trish Gorely, Joanna McParland, Julie Brittenden, Ebuka M Anieto, Lorna Booth, Cathy Gormal, Jeremy Dearling, Candida Fenton, Sarah Audsley, Kimberley Fairer, Lindsay Bearne, Dawn A Skelton

“…Secondary outcomes: clinical-/patient-reported outcomes. Data sources Seven primary studies databases; Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, Health Technology Assessment Database and Trial Registers to 31 August 2023. …”
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The Challenges of Safety Culture: No more risk! by Julija Melnikova

“…These factors by themselves are the definite source of disaster. People are not able to avoid their impacts: different crashes, accidents, fires. …”
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Demand and Influencing factors for community health services during chemotherapy of patients with advanced cancer by Qianqian Li, Xunrui Chen, Wenying Zhang, Haihua Yuan, Yanjie Zhang, Bin Jiang, Feng Liu

“…Logistic regression analysis showed that educational level and disposable monthly household income significantly influenced psychological demand, while age and source of medical expenses influenced medical care demand, and age and patient group participation affected social support demand (P < 0.05). …”
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Impact of short-term aircraft noise on cardiovascular disease risk in the area surrounding London Heathrow airport: the RISTANCO epidemiological study by Xiangpu Gong, Nicole Itzkowitz, Calvin Jephcote, Kathryn Adams, Glory O Atilola, John Gulliver, Marta Blangiardo, Anna Hansell

“…Main outcome measures Cardiovascular disease hospitalisations and mortality. Data sources Aircraft noise levels modelled using a standard noise model for: (1) daily equivalent continuous sound levels at different times of day; (2) daily number of events above defined noise thresholds (2018 only). …”
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Glucocorticoids and antivirals for HBV reactivation in onco-hematologic patients by Michela di Fonzo, Andrea Marengo, Alfredo Marzano, Antonella Ferrari, Bruno Monarca, Gianfranco delle Fave, Massimo Marignani

“…In this later autopsy detected cirrhosis, not evident at presentation. This clinical experience suggests that in patients with &lt;span&gt;onco-hematological&lt;/span&gt; and persistent liver function tests alterations in spite of effective antiviral response, glucocorticoids could control the effects of immune response. …”
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Multiscale phytoplankton dynamics in a coastal system of the eastern English Channel: the Boulogne-sur-Mer coastal area by K. Robache, Z. Hubert, C. Gallot, C. Gallot, A. Epinoux, A. P. Louchart, A. P. Louchart, J.-V. Facq, A. Lefebvre, M. Répécaud, V. Cornille, F. Verhaeghe, Y. Audinet, L. Brutier, F. G. Schmitt, L. F. Artigas

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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c... by Ming Zhang, Yani Su, Pengfei Wen, Xiaolong Shao, Peng Yang, Peng An, Wensen Jing, Lin Liu, Zhi Yang, Mingyi Yang

“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. The m6aCRLncs linked to EC were identified through co-expression analysis. …”
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The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization by Landry L. Tsoumtsa Meda, Luce Landraud, Serena Petracchini, Stéphane Descorps-Declere, Emeline Perthame, Marie-Anne Nahori, Laura Ramirez Finn, Molly A. Ingersoll, Rafael Patiño-Navarrete, Philippe Glaser, Richard Bonnet, Olivier Dussurget, Erick Denamur, Amel Mettouchi, Emmanuel Lemichez

“…In addition, functional analysis of the cnf1-positive clinical strain EC131GY ST131-H30Rx/C2 and a cnf1-deleted isogenic strain showed no detectable impact of the CNF1 gene on bacterial fitness and inflammation during the acute phase of bladder monoinfection. …”
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Targeting hyperlipidemia: A polarity-driven ternary extraction of Apium graveolens bioactives—A coupled in-vivo, in-vitro and in-silico investigation by Nargis Sultana Chowdhury, Tasnuva Sharmin Zaman, Rifah Noor Chowdhury, Md Abdur Rahman, Sheikh Rakibul Alam, Romana Akter, Md. Nazmus Samdani, Syeda Sadia Afrin, Md. Rafat Tahsin, Fahima Aktar, Ishrat Jahan, Nasiba Binte Bahar, Salehuddin Ayubee, Umme Habiba Ria, Md Zakir Sultan, Mohammad Borhan Uddin, Jakir Ahmed Chowdhury, Md. Selim Reza, Abu Asad Chowdhury, Shaila Kabir, Md. Shah Amran

“…The findings of the in-silico studies revealed that the 3 top performing compounds (i.e. apiumoside, apiin and graveobioside B) showed high binding affinity to selected anti hyperlipidemic targets HMG CoA reductase and peroxisome proliferator-activated receptor-Alpha (PPAR-Alpha) with a very stable condition in the molecular dynamic simulation against the selected targets. …”
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Molecular classification of head and neck squamous cell carcinoma based on hypoxia-related genes and clinical significance of STC2 by ZHU Jianing, WANG Tiantian, ZHANG Rui, SONG Hongquan

“…Objective To construct a molecular classification system for head and neck squamous cell carcinoma (HNSCC) utilizing hypoxia-related gene (HAG) expression profiles, and to comprehensively examine the clinicopathological significance and biological functions of the hypoxia gene stanniocalcin 2 (STC2) in HNSCC. …”
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