Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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Beyond access: assessing WASH service delivery models in healthcare facilities of North Mecha, Dera, and Farta, Ethiopia by Abireham Misganaw Ayalew

“…A total of 384 citizens were selected through a systematic random sampling technique to participate in the survey. …”
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Multi-omics analyses reveal fecal microbial community and metabolic alterations in finishing cattle fed probiotics-fermented distiller’s grains diets by Rong Zhang, Shihui Mei, Guangxia He, Miaozhan Wei, Lan Chen, Ze Chen, Min Zhu, Bijun Zhou, Kaigong Wang, Zhentao Cheng, Chunmei Wang, Erpeng Zhu, Chao Chen

“…ABSTRACT Distiller’s grains (DG) are a potential source of animal feeds, and many studies have indicated positive regulatory roles of feeding DG diets in animal breeding. …”
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Uncovering the role of Gpr45 in obesity regulation by Eva O. Karolczak, Chia Li, Ivan C. Alcantara, Isabel M. Cohen, Claire Gao, Cuiying Xiao, Abigail I. Goldschmidt, Cynthia A. Pinkus, Junjie Li, Monica M. Li, Ryan M. Esquejo, Jean-Philippe Fortin, Kendra K. Bence, Marc L. Reitman, Michael J. Krashes

“…Underscoring this, agonists for GPCRs have recently revolutionized the treatment of diabetes and obesity. The rampant success of these compounds has invigorated interest in identifying additional GPCRs that modulate appetite and body weight homeostasis. …”
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Effects of exercise with music in frail older adults: a systematic review and meta-analysis by NamHee Kim, Gwang Suk Kim, Min Kyung Park, Layoung Kim, Jae Jun Lee, Seungbum Yang

“…This study evaluated the impact of exercise with music on the physical and emotional health of frail, community-dwelling older adults.Design A systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines.Data sources MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Embase, Cochrane Library, PsycINFO, Google Scholar and the Virginia Henderson International Nursing Library were last searched on 14 March 2025.Eligibility criteria for selecting studies We included randomised controlled trials (RCTs) and non-RCTs that applied exercise with music to community-dwelling frail older adults.Data extraction and synthesis Five independent reviewers used standardised methods to search, screen and code included studies. …”
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Understanding the political economy of reforming global health initiatives – insights from global and country levels by Sophie Witter, Natasha Palmer, Rosemary Jouhaud, Shehla Zaidi, Severine Carillon, Rene English, Giulia Loffreda, Emilie Venables, Shifa Salman Habib, Jeff Tan, Fatouma Hane, Maria Paola Bertone, Seyed-Moeen Hosseinalipour, Valery Ridde, Asad Shoaib, Adama Faye, Lilian Dudley, Karen Daniels, Karl Blanchet

“…Funders have not collaborated to enable reforms, despite concerns amongst a number of them, because of the helpful functional role of GHIs, which serves funder interests. …”
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Computational Phenotyping of Obstructive Airway Diseases: A Systematic Review by Bashir MBA, Milani GP, De Cosmi V, Mazzocchi A, Zhang G, Basna R, Hedman L, Lindberg A, Ekerljung L, Axelsson M, Vanfleteren LEGW, Rönmark E, Backman H, Kankaanranta H, Nwaru BI

“…COPD phenotypes involved lung function, emphysematous changes, smoking, comorbidities, and daily life impairment. …”
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In Vivo Measurements Reveal Increased Nucleus Pulposus Lactate and Oxygen Concentrations in a Goat Model of Intervertebral Disc Degeneration by Karthikeyan Rajagopal, Thomas P. Schaer, Kyle D. Meadows, Madeline Boyes, Rachel Hilliard, John C. O'Donnell, George R. Dodge, Dmitriy Petrov, Dawn M. Elliott, Robert L. Mauck, Lachlan J. Smith, Neil R. Malhotra

“…There were significant positive correlations between MRI grade and both NP oxygen and lactate levels. Discussion We successfully adapted techniques including surgical placement, equilibration time, flow rate, and detection method for in situ measurement of oxygen, glucose, and lactate in a goat model of disc degeneration. …”
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Viable but nonculturable state in the zoonotic pathogen Bartonella henselae induced by low-grade fever temperature and antibiotic treatment by Yuze Gou, Yuze Gou, Dongxia Liu, Dongxia Liu, Yuxian Xin, Yuxian Xin, Ting Wang, Jiaxin Li, Yiwen Xi, Xiaoling Zheng, Tuanjie Che, Ying Zhang, Ying Zhang, Tingting Li, Jie Feng, Jie Feng

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Relaxation-exchange magnetic resonance imaging (REXI): a non-invasive imaging method for evaluating trans-barrier water exchange in the choroid plexus by Xuetao Wu, Qingping He, Yu Yin, Shuyuan Tan, Baogui Zhang, Weiyun Li, Yi-Cheng Hsu, Rong Xue, Ruiliang Bai

“…However, non-invasive imaging techniques to assess its function remain limited. This study was conducted to develop a novel, contrast-agent-free MRI technique, termed relaxation-exchange magnetic resonance imaging (REXI), for evaluating CP-CSF water transport, a potential biomarker of CP function. …”
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The BoRG-JWST Survey: Abundance and Mass-to-light Ratio of Luminous z = 7–9 Galaxies from Independent Sight Lines with NIRSpec by Sofía Rojas-Ruiz, Micaela Bagley, Guido Roberts-Borsani, Tommaso Treu, Steven L. Finkelstein, Takahiro Morishita, Nicha Leethochawalit, Charlotte Mason, Eduardo Bañados, Michele Trenti, Massimo Stiavelli, L. Y. Aaron Yung, Pablo Arrabal Haro, Rachel S. Somerville, Christian Soto

“…We present new results on the rest-frame UV luminosity function (UVLF) and stellar mass-to-light ( M / L ) ratio of bright ( M _UV  ≲ −20 mag) spectroscopically confirmed galaxies at z  = 7–9 derived from the BoRG-JWST survey, a unique data set of NIRSpec prism follow-up of Hubble Space Telescope (HST)–selected sources from random-pointing imaging. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Analysing the contribution of trees and green spaces to household nutrition security in eThekwini, KwaZulu-Natal, South Africa by Qhelile Ntombikayise Bhebhe, Qhelile Ntombikayise Bhebhe, Muthulisi Siwela, Temitope O. Ojo, Temitope O. Ojo, Simphiwe Innocentia Hlatshwayo, Simphiwe Innocentia Hlatshwayo, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Rob Slotow, Mjabuliseni S. C. Ngidi, Mjabuliseni S. C. Ngidi, Mjabuliseni S. C. Ngidi

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Vitamin K Epoxide Reductase Complex (VKORC1) Electrochemical Genosensors: Towards the Identification of <i>1639 G>A</i> Genetic Polymorphism by Tiago Barbosa, Stephanie L. Morais, Renato Carvalho, Júlia M. C. S. Magalhães, Valentina F. Domingues, Cristina Delerue-Matos, Hygor Ferreira-Fernandes, Giovanny R. Pinto, Marlene Santos, Maria Fátima Barroso

“…A clear differentiation between A/A, G/A and G/G genotypes in biological samples was successfully identified by his novel device.…”
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Association of Omega-3 Index and Blood Cell Count-Derived Systemic Inflammatory Indexes among Testicular Germ Cell Tumor Survivors by Milica Zeković, Marko Živković, Marija Takić, Sanja Stanković, Nebojša Bojanić, Aleksandar Janičić, Uroš Bumbaširević

“…Background and objectives: Although testicular cancer is considered the paradigm of highly curable malignancy, treatment-induced adverse effects and potential impairment of gonadal function may cause non-negligible long-term health repercussions, including metabolic disturbances and cardiovascular sequelae. …”
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Metallurgical Waste for Sustainable Agriculture: Converter Slag and Blast-Furnace Sludge Increase Oat Yield in Acidic Soils by Olga V. Zakharova, Peter A. Baranchikov, Svetlana P. Chebotaryova, Gregory V. Grigoriev, Nataliya S. Strekalova, Tatiana A. Grodetskaya, Igor N. Burmistrov, Sergey V. Volokhov, Denis V. Kuznetsov, Alexander A. Gusev

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Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad... by Fernanda Ginani, Diego Moura Soares, Carlos Augusto Galvão Barboza

“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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Rapid and sensitive determination of bongkrekic acid with molecularly imprinted polymer-coated wooden-tip electrospray ionization mass spectrometry by Chunfei Zhong, Xinyan Li, Fan Zhang, Ning Liu, Jiewei Deng, Yunyun Yang, Tiangang Luan

“…The practical application of the method was confirmed through the successful analysis of real-world samples, including tap water, wastewater from a food processing factory, and the aqueous extracts of food samples, with BA detected at 0.296 µg/L in Tremella. …”
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Analysis of the Stability of the Banking Sector of Azerbaijan in Conditions of Economic Crisis Based on the Econometric Model by S. M. Huseynova, T. Ja. Hajizada

“…Information was taken from a number of sources: 1) Official website of the Central Bank of Azerbaijan; 2) Official website of Ministry of Finance; 3) Official website of Azerbaijan State Statistics Committee; 4) Reports on the development of the banking sector and banking supervision. …”
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Transcription Factor LjWRKY50 Affects Jasmonate-Regulated Floral Bud Duration in <i>Lonicera japonica</i> by Yanfei Li, Yutong Gan, Guihong Qi, Wenjie Xu, Tianyi Xin, Yuanhao Huang, Lianguo Fu, Lijun Hao, Qian Lou, Xiao Fu, Xiangyun Wei, Lijun Liu, Chengming Liu, Jingyuan Song

“…<i>Lonicera japonica</i> Thunb. is a traditional Chinese medicinal herb whose floral buds are the primary source of pharmacological compounds that require manual harvesting. …”
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