Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
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Biomimetic 3D printable electrochemical filament integrated with CuO nanopowder for enzyme-free biosensing by Leonidas Papagiannakopoulos, Vasiliki Polyzopoulou, Loizos Tsolakis, Eleni Sorkou, Eleni Koukouviti, Anastasios Economou, Christos Kokkinos

“…Meanwhile, LA voltammetric detection relied on the characteristic increases in the redox signals of CuO. …”
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Development of smart samplers and their comparison to dried serum spots for the analysis of growth hormone releasing hormone analogs using LCHRMS/MS by Christina Johannsen, Anna Kha Tu Nguyen, Sasha Shabani, Inger Oulie, Siri Dørum, Yvette Dehnes, Leon Reubsaet, Trine Grønhaug Halvorsen

“…DSS and smart samplers were compared for extraction efficiency, precision, and detection capabilities. Various extraction approaches were evaluated to optimize analyte recovery followed by a blind sample study to assess detection capability at unknown concentrations. …”
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P. berghei telomerase subunit TERT is essential for parasite survival. by Agnieszka A Religa, Jai Ramesar, Chris J Janse, Artur Scherf, Andrew P Waters

“…Average telomere length was measured in several Plasmodium species using Telomere Restriction Fragment (TRF) analysis. TERT and TR were detected in blood stages and an average telomere length of ∼ 950 bp established. …”
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C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS‐STING Pathway by Yue Wang, Ting Xu, Wenjun Wang

“…Histopathological examination, level of inflammation, cGAS‐STING pathway, and gut barrier function were detected in mice and cells. Results C9orf72 overexpression in mice attenuated DSS‐induced colitis and intestinal epithelial barrier damage by stimulating ZO‐1 and Occludin expression. …”
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Endodontic treatment of teeth with a wide apical opening – a clinical case by V. A. Popov, E. S. Pestova, S. A. Anisimova

“…The presented clinical case demonstrates the successful endodontic treatment of a tooth in a teenager, in which treatment tactics aimed at stimulating apexification were applied. …”
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Development of a Rapid UPLC Method for Analysis of Carotenoids in Goji Berry Extract and Evaluation of Their Transformation Affected by Saponification by Bo-Yang Hsu, Chia-Hui Lin, Tsai-Hua Kao

“…This method successfully separates 17 carotenoids and their esters within 21 min using a Sunrise C30 column, with detection at 450 nm, a flow rate of 1.3 mL/min, and a column temperature of 25 °C. …”
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In vitro regeneration and phytochemical evaluation of pippali (Piper longum) for conservation and therapeutic applications by ARIJITA MOHANTY, JYOTI PRAKASH SAHOO, KAILASH CHANDRA SAMAL

“…Infrared (IR) absorption analysis identified functional groups such as alcohols, amides, alkanes and carboxylic acids. …”
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Identification and odor exposure regulation of odorant-binding proteins in Picromerus lewisi by Shan-Cheng Yi, Jia-Ling Yu, Sara Taha Abdelkhalek, Sara Taha Abdelkhalek, Zhi-Rong Sun, Man-Qun Wang

“…This implies that these PlewOBPs may have an olfactory function in detecting S. litura-infested tobacco plants. …”
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Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques by Renata F. Leoni, Kelley C. Mazzetto-Betti, Afonso C. Silva, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto

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The battle between rotavirus and its host for control of the interferon signaling pathway. by Michelle M Arnold, Adrish Sen, Harry B Greenberg, John T Patton

“…Viral pathogens must overcome innate antiviral responses to replicate successfully in the host organism. Some of the mechanisms viruses use to interfere with antiviral responses in the infected cell include preventing detection of viral components, perturbing the function of transcription factors that initiate antiviral responses, and inhibiting downstream signal transduction. …”
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A Fully Printable Strain Sensor Enabling Highly‐Sensitive Wireless Near‐Field Interrogation by Hassan A. Mahmoud, Hussein Nesser, Tarek M. Mostafa, Shehab Ahmed, G. Lubineau

“…Abstract Wireless, passive, and flexible strain sensors can transform structural health monitoring across various applications by eliminating the need for wired connections and active power sources. Such sensors offer the dual benefits of operational simplicity and high‐function adaptability. …”
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GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization by Luca Franchini, Joseph J. Porter, John D. Lueck, Cesare Orlandi

“…We optimized assay conditions and developed an all-in-one vector employing cloning methods to ensure the correct expression ratio of GzESTY components. GzESTY successfully assessed activation of a library of ligand-activated GPCRs, detecting both full and partial agonism, and responses from endogenous GPCRs. …”
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The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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Development of grain drink technology based on unsteamed buckwheat by G. M. Kerimova, I. A. Fomenko, A. R. Pivchenko, I. R. Sokolov

“…In the finished drink, the final indicators of the content of  protein, fat, reducing substances, dry substances have been detected. The finished product is also a source  of soluble dietary fiber, which has a positive effect on the human microbiome.…”
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Introducing the English EmpaToM task: A tool to assess empathy, compassion, and theory of mind in fMRI studies by Dorottya Lantos, Celeste Costa, Matthew Briglia, Pascal Molenberghs, Philipp Kanske, Tania Singer

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Levels of amino acids and homoarginine in the venous basins of the brain and the heart muscle in patients with ischemic heart disease by N. S. Molchan, T. Yu. Reypol'skaya, T. F. Subbotina, A. A. Zhloba, Yu. S. Polushin

“…Under the conditions of circulatory disorders and coronary heart disease (CHD), amino acids acquire additional value as a source of intermediates of Krebs cycle, participating in cell energetics. …”
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Enzymatic system of glucose metabolism in Gluconobacter oxydans strain DHA3-9 by Li Qianyan, Lu Xiangfeng, Zhang Pengcheng, Sun Lingyan, Liu Yu, Ma Xiaohang

“…Pyruvate and acetate were detected in the products of mutant whereas none of such products were found in wild type culture. …”
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ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans. by Lina Zhao, Lorenz A Fenk, Lars Nilsson, Niko Paresh Amin-Wetzel, Nelson Javier Ramirez-Suarez, Mario de Bono, Changchun Chen

“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
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