Liposomes as Imaging Agents of Inflammation and Oxidative Stress in Bone Implants by Delia Danila, Patricia S. Pardo, R. Devesh Kumar Misra, Aladin M. Boriek

“…Research is ongoing to improve the design and functionality of liposomes. They can potentially monitor bone implants as non-invasive imaging agents, enabling early detection of complications and timely interventions. …”
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PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm by Naeem Shirmohammady, Habib Izadkhah, Ayaz Isazadeh

“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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A survey on the applications of transfer learning to enhance the performance of large language models in healthcare systems by Anmol Rahujo, Daniya Atif, Syed Azeem Inam, Abdullah Ayub Khan, Sajid Ullah

“…This research analyzes different transfer learning methods, including inductive, transductive, and unsupervised techniques, while demonstrating their effectiveness in detecting COVID-19 from chest X-rays and multi-source disease evaluation. …”
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Presepsin as a sepsis biomarker by K. A. Trunova

“…The review includes 42 Russian-language and English-language  sources. Particular attention was paid to comparative studies on the role of presepsin and other bio-markers in the diagnosis of sepsis.Results. …”
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Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry. by Carolina Fontanarosa, Francesca Pane, Nunzio Sepe, Gabriella Pinto, Marco Trifuoggi, Marta Squillace, Francesco Errico, Alessandro Usiello, Piero Pucci, Angela Amoresano

“…The validated method was then successfully applied to the simultaneous detection of d-Asp, l-Asp and NMDA in mouse brain tissues. …”
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Background of standardization and regulation of training and use of pharmaceutical regular resource potential in XI–XVI centuries by M. S. Ponomarenko, O. S. Soloviov, T. M. Krasnianska, Yu. M. Grygoruk

“…The main stages of development of the property (material) and human resources to provide medical treatment and patients have been detected. The basic steps of transformation and delimitation of professional functions pharmacist-physician have been set. …”

Investigation and Application of Water-Saving Monitoring Technology in Public Institutions by WANG Kang, ZHENG Yongjie, ZHANG Zhen, TANG Yanping, SONG Wenhao, GUO Xiaoming

“…Considering the characteristics of water use and the current situation of water facilities in public institutions,this study comprehensively employs the Internet of Things (IoT),cloud deployment,databases,three-dimensional (3D) visualization,and other advanced techniques to create a water-saving reconstruction scheme with integrated software and hardware for public institutions.Therefore,a smart water management platform for public institutions is built to implement advanced water-saving concepts and improve the water management level.The main research results are as follows:① By intelligent remote monitoring equipment,the multiclass water measurement network is designed to realize the fine collection of zonal water use data;② this study designs a reconstruction scheme of water facilities and explores the utilization mode of unconventional water sources to improve the utilization efficiency of water resources;③ multiple algorithms and statistical methods are used to analyze the time series of water use data,and thus this study realizes the analysis of pipeline network leakage and damage,identification of water use anomalies,and water-saving statistical analysis,and the investigation of water use laws;④ the platform with functions of monitoring and early warning is established to achieve real-time remote monitoring of water use,statistical analysis of historical water use,and identification and warning of pipe network leakage,so as to detect water anomalies in time and save water.The research results are first applied to the construction of the water-saving institution of the Pearl River Water Resources Commission to build a benchmark for the construction of water-saving institutions in the southern region.On the basis of application experience,the comprehensively integrated monitoring technology for water-saving in public institutions is developed,which provides a new idea for public institutions to save water.…”
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Identifying pathogenicity of human variants via paralog-based yeast complementation. by Fan Yang, Song Sun, Guihong Tan, Michael Costanzo, David E Hill, Marc Vidal, Brenda J Andrews, Charles Boone, Frederick P Roth

“…Here we systematically examine the question of whether complementation assays based on paralogy relationships can expand the number of human disease genes with functional variant detection assays. We tested over 1,000 paralogous human-yeast gene pairs for complementation, yielding 34 complementation relationships, of which 33 (97%) were novel. …”
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FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation by Mattia Rosso, Gemma Fernández‐Rubio, Peter Erik Keller, Elvira Brattico, Peter Vuust, Morten L Kringelbach, Leonardo Bonetti

“…In this study, FREQ‐NESS is applied to source‐reconstructed magnetoencephalography (MEG) data during resting state and isochronous auditory stimulation. …”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review... by Mei-Xue Dong, Qing-Chuan Hu, Peng Shen, Jun-Xi Pan, You-Dong Wei, Yi-Yun Liu, Yi-Fei Ren, Zi-Hong Liang, Hai-Yang Wang, Li-Bo Zhao, Peng Xie

“…Subgroup analysis, meta-regression and sensitivity analysis were performed to explore sources of heterogeneity. Funnel plot, Trim and Fill method and Egger's test were obtained to detect publication bias.…”
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Innovative Device for Indocianyne Green Navigational Surgery by Cătălin Aliuș, Nicolae Bacalbașa, Cristian Bălălău

“…Dynamic reality has been integrated into developing surgical techniques, with the goals of providing increased intraoperative accuracy, easier detection of critical anatomical landmarks, and better general results for the patient. …”
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Empirical Therapy of Complicated Pyelonephritis by V. A. Beloborodov, V. A. Vorobev, P. V. Opanasyuk

“…Aminoglycosides showed the best result as a combination therapy with cephalosporins – 100 % (n = 3) of success. Based on multivariate logistic regression analysis, it was established that the detection of microhematuria and uremia in clinical analyzes upon admission to the hospital increases the likelihood of empirical monotherapy with third-generation cephalosporins by 20 % and 27 %, respectively.Conclusion. …”
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Analysis of CMOS Extended-Gate Field-Effect Transistor With On-Chip Window Based on Uricase/RuO₂ Sensing Film by Po-Yu Kuo, Yung-Yu Chen, Wei-Hao Lai, Chun-Hung Chang

“…The sensing window was composed of six metal layers and functionalized with the ruthenium dioxide (RuO₂) thin film and uricase for uric acid detection. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals by Edanur Güler–Ekmen, İsmail Çağrı Yılmaz, Talat Güler, Derya Güler, Mehtap Özçelik

“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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Substandard Language Phenomena in Artistic Discourse by Anzhelika V. Korolkova, Tatyana S. Novikova

“…The substandard is currently becoming a source of replenishment of the stylistically reduced layer of modern colloquial speech.…”
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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. by Michele Vacca, Simona D'Amore, Giusi Graziano, Andria D'Orazio, Marica Cariello, Vittoria Massafra, Lorena Salvatore, Nicola Martelli, Stefania Murzilli, Giuseppe Lo Sasso, Renato Mariani-Costantini, Antonio Moschetta

“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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