HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer by Qing Wang, Maha Ayyoub, Olivia Le Saux, Paola Bonaventura, Isabelle Treilleux, Nicolas Chopin, Clarisse Dubois, Virginie Mutez, Nicolas Chuvin, Yann Estornes, Jenny Valladeau-Guilemond, Stephane Depil, Nicolas Gadot, Marie Michelas, Audrey Page, Olivier Tabone, Marie Delles, Sarah Moran, Thibault Richard, Marjorie Lacourrège, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez

“…A specific immunopeptidomics approach was developed to detect epitopes on human leukocyte antigens (HLA) molecules. …”
Get full text

Encoding arbitrary phase profiles to 2D diffraction orders with controllable polarization states by Zhao Ruizhe, Li Xin, Geng Guangzhou, Li Xiaowei, Li Junjie, Wang Yongtian, Huang Lingling

“…Meanwhile, it may promote the realization of achieving various functionalities parallelly such as spectral-polarization imaging or phase-polarization detection and enhance the capabilities of optical communication systems.…”
Get full text

Facile construction of dual‐response super‐resolution probes for tracking organelles dynamics by Daili Liu, Guiqian Fang, Yanfeng Wang, Caicai Meng, Zhidong Liu, Qixin Chen, Xintian Shao

“…Herein, a customizable engineering toolkit is developed for the facile assembly of SIM probes suitable for subcellular component detection. This toolkit is used to customize a fluorescent molecule, CPC (coumarin–phenylhydrazine–carboxyl), capable of simultaneously monitoring peroxynitrite (ONOO−) and polarity distribution in mitochondria and lipid droplets (LDs), respectively, through functional ON–OFF mechanisms. …”
Get full text

Evolution of Innovative Surgical Techniques Using the Example of Selective Splenorenal Anastomosis Surgery by A. Yu. Anisimov, F. B. Mavlonov, D. E. Erkinova, A. I. Andreev, R. A. Ibragimov, E. Yu. Mandryka

“…RELEVANCE Despite the obvious successes of transjugular intrahepatic portosystemic shunt and orthotopic liver transplantation in some high-tech centers of the Russian Federation, the relevance of substantiating the use of selective splenorenal anastomoses in the treatment plan for portal hypertension, when hundreds of patients return to emergency surgery departments every year after conservative treatment with new episodes of bleeding, liver failure and high mortality rates, is beyond doubt.AIM OF THE STUDY To substantiate the viability of the selective splenorenal anastomosis operation by improving the technique of performing the intraoperative vascular maneuver exposure and venous reconstruction through the use of original modern innovative approaches.MATERIAL AND METHODS A retrospective controlled clinical study included 56 patients with intrahepatic portal hypertension with relatively preserved liver function, in whose complex treatment program for secondary prevention of bleeding, various options for selective splenorenal bypass surgery were used. …”
Get full text

Forensic analysis of mixed semen and vaginal fluids via ATR-FTIR spectroscopy for identification purposes in sexual aggression cases by Tuğba Ünsal Sapan, İrem Hersekli

“…Spectral markers specific to vaginal fluid and mixed samples were successfully distinguished. Conclusion A notable finding of the study was the identification of the PSA/Fructose functional group as a biochemical marker indicative of seminal fluid within mixed samples containing vaginal secretions. …”
Get full text

A Novel Method for Extraction of Galegine by Molecularly Imprinted Polymer (MIP) Technique Reinforced with Graphene Oxide and Its Evaluation Using Polarography by M. Azimi, M. Ahmadi Golsefidi, A. Varasteh Moradi, M. Ebadii, R. Zafar Mehrabian

“…It is noteworthy that this developed method was used successfully to determine galegine extracted from Galega officinalis L.…”
Get full text

Specificities of transplantation of kidneys procured from donors with situs inversus totalis: A case report and review of the literature by Petrović Milica, Rabrenović Violeta, Stamenković Dušica, Vavić Neven, Kovačević Zoran, Ignjatović Ljiljana, Jovanović Dragan, Antić Svetlana, Milović Novak, Tomić Aleksandar, Bančević Vladimir

“…A 20-month follow-up of the donor’s kidney and graft in the recipient proved that their functions were excellent. Conclusion. In donors with previously diagnosed SIT the multidisciplinary approach, preoperative evaluation of the patient and detection of possible vascular anomalies are required to provide maximum safety for the donor.…”
Get full text

Maturity Classification and Quality Determination of Cherry Using VNIR Hyperspectral Images and Comprehensive Chemometrics by Yuzhen Wei, Siyi Yao, Feiyue Wu, Qiangguo Yu

“…In this research, hyperspectral imaging (380–1030 nm) technology was applied to visually detect the sweetness and acidity of cherry. To improve the imaging performance, two spectral pretreatment methods (wavelet transform, standard normal variable transformation and detrend), three feature selection methods (successive projection algorithm, genetic algorithm, and shuffled frog leaping algorithm), and four regression modeling methods (principal components regression, partial least squares regression, least square-support vector regression, convolutional neural network) were employed and compared. …”
Get full text

Daily and seasonal rhythms in immune responses of splenocytes in the freshwater snake, Natrix piscator. by Manish Kumar Tripathi, Ramesh Singh, Atanu Kumar Pati

“…The enhancement of immune function coinciding with one of its crucial reproductive phases might be helping it to cope with the seasonal stressors, including abundance of pathogens, which would otherwise jeopardize the successful reproduction and eventual survival of the species.…”
Get full text

Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy by Xiaohong Liu, Yue Sun, Boxu Lin, Hao Xiong, Xinyue Lu, Binghe Tan, Chenglin Zhang, Mingyao Liu, Juliang Qin, Na Zhang, Bing Du

“…Abstract Background Chimeric antigen receptor T (CAR-T) cell therapy has shown remarkable success in treating hematologic malignancies. However, its efficacy against solid tumors remains limited. …”
Get full text

In vitro biological activities of silver nanoparticles using methanolic leaf extract of Plumeria rubra by Abhinash Marukurti, Alavala Matta Reddy, Pangi Vijaya Nirmala, Dasari Kalyani, K. Ramaneswari, I. J. N. Padmavathi, L. Pradeepthi Pemmaraju, Gotham Samuel Silvanus, Buddha Sai Keerthana, Shaik Farhana, D. Ramachandran, B. Mallikarjuna, Phanindra Babu Kasi

“…The phytochemistry of PR extract was observed using qualitative screening, Fourier transform infrared spectroscopy (FTIR), and gas chromatography with flame ionisation detection (GC-FID). The observed surface plasmon resonance using UV-visible spectroscopy confirmed the formation of PR-AgNPs, and the surface functionalization identified with FTIR correlated with the phytochemistry of the PR extract. …”
Get full text

Acetone gas sensor based on chitosan-metal-organic framework mixed matrix membranes for diabetes diagnosis by Lamia A. Siddig, Ashraf Ali, Shaikha S. Al Neyadi, Yaser E. Greish, Stefan Wuttke, Saleh T. Mahmoud

“…Detecting diabetes in its early stages through non-invasive methods remains a major challenge for researchers. …”
Get full text

Metallurgical Waste for Sustainable Agriculture: Converter Slag and Blast-Furnace Sludge Increase Oat Yield in Acidic Soils by Olga V. Zakharova, Peter A. Baranchikov, Svetlana P. Chebotaryova, Gregory V. Grigoriev, Nataliya S. Strekalova, Tatiana A. Grodetskaya, Igor N. Burmistrov, Sergey V. Volokhov, Denis V. Kuznetsov, Alexander A. Gusev

Get full text

Epidemiology of Disability of Adult Population in the Russian Federation by S. N. Puzin, M. A. Shurgaya, N. V. Dmitrieva, G. E. Pogosyan, I. V. Lyalina, A. M. Mammaraeva, T. A. Ivanova, L. S. Idrisova

“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
Get full text

Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage by Natalia Lazzarin, Costanzo Moretti, Giovanna De Felice, Elena Vaquero, Dario Manfellotto

“…Our data support the hypothesis that in patients with RM the presence of TAI is an indirect sign of a subtle thyroid dysfunction detectable by a specific test. This test give the possibility to identify women with RM in which specific therapeutic approaches could effectively improve the possibility for a successful pregnancy.…”
Get full text

Construction of a myocardial and skeletal muscle-specific Cyr61 gene knockout mouse model by XU Diyan, ZHANG Wenli, ZUO Yidan, SU Zhen

“…The skeletal muscle function of Cyr61 knockout mice was evaluated and following related indicators in the myocardium and skeletal muscle were detected by Western blot: Aging (p53, p21),inflammatory response (TNF-α,IL-18,IL-1β),fibrosis (vimentin,TGF-β,α-SMA,COL1). …”
Get full text

MicroRNAs obtained from cervical swabs in predicting preterm birth by Rosalia Purbandari, Suheni Ninik Hariyati

“…Under stress conditions, their regulatory functions become significant, linking them to disease states. …”
Get full text

Mobile health apps for skin cancer triage in the general population: a qualitative study on healthcare providers’ perspectives by Tobias E. Sangers, Marlies Wakkee, Folkert Moolenburgh, Tamar Nijsten, Marjolein Lugtenberg

“…Conclusions Although HCPs perceive pivotal risks related to the implementation of mHealth apps, they also foresee important benefits when implemented successfully. In order for HCPs to endorse those apps, emphasis must be placed on integrating accurate mHealth apps with accessible and inclusive design and functionality into clinical practice, factors that currently appear to be largely unmet.…”
Get full text

Challenges and Management Strategies for Mediterranean Cork Oak Forests: Impacts of Climate Change, Human Activities, and Invasive Species – A Review by Mesfin Boja, Kaouther Mechergui, Wahbi Jaouadi, Youssef Ammari

“…Long-term monitoring and proactive management strategies are crucial for early detection and control of invasive species and diseases, which will help mitigate their impacts and support forest health. …”
Get full text

Target Selection, Homokaryotic Isolation, and Screening Methods for Gene Editing in the Destructive Global Pathogen, <i>Phytophthora cinnamomi</i> by Aayushree Kharel, Mark Ziemann, Jim Rookes, David M. Cahill

“…While gene editing has emerged as a powerful tool for functional genomics in various <i>Phytophthora</i> species, its application in <i>P. cinnamomi</i> remains underexplored. …”
Get full text