-
1461
Optimization of an Antiviral Treatment Regimen for Immunological Nonresponders Through HIV-DNA Resistance Testing: A Case Report
Published 2025-05-01“…Baseline measurements revealed an HIV RNA count of 79 400 copies/mL and a CD4+ T-lymphocyte count of 8 cells/μL. Despite successful viral suppression with HIV RNA levels remaining below the detectable threshold for 9 consecutive years following the initiation of antiretroviral therapy, the patient's CD4+ T lymphocyte count persistently remained below 200 cells/μL. …”
Get full text
Article -
1462
Aortic Dissection a Day after Renal Transplantation
Published 2025-01-01“…The successful management of this patient underscores the potential for favorable outcomes with prompt diagnosis and intervention.…”
Get full text
Article -
1463
Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat
Published 2025-05-01“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
Get full text
Article -
1464
Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells
Published 2025-01-01“…Here, we established a monoclonal cell line that consistently expresses Cas9 and can be used for screens to determine gene function or antiviral activity. <b>Methods</b>: We used this system to perform the successful gene editing of seven genes and subsequent testing for potential antiviral effects, using a simple single-guide RNA (sgRNA) transfection and subsequent virus infection. …”
Get full text
Article -
1465
Dynamic Monitoring of Goaf Stress Field and Rock Deformation Driven by Optical Diber Sensing Technology
Published 2025-04-01“…By coupling the key stratum fracture mechanics model with the subsidence trajectory function model, a theoretical model is established to accurately describe spatial stress evolution during coal mining. …”
Get full text
Article -
1466
Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry
Published 2025-05-01“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
Get full text
Article -
1467
An Activated Glassy Carbon Electrode for Rapid, Simple, and Sensitive Voltammetric Analysis of Diclofenac in Tablets
Published 2025-06-01“…To show the practical application of the method, DCF was successfully determined in commercially available pharmaceutical preparations with the standard addition method.…”
Get full text
Article -
1468
Features of the Parameters of 24-Hours pH-Impedance and High-Resolution Esophageal Manometry in Patients with Barrett's Esophagus on Proton Pump Inhibitors
Published 2023-06-01“…Evaluation of the results of high-resolution esophageal manometry showed that violations of the structure and function of the esophago-gastric junction were detected in 21 patients out of 52. …”
Get full text
Article -
1469
-
1470
Developments in nanotechnology approaches for the treatment of solid tumors
Published 2025-05-01“…Beyond drug delivery, nanotechnology plays a crucial role in the theranostic field due to the functionalization of specific materials that combine tumor detection and targeted treatment features. …”
Get full text
Article -
1471
Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods
Published 2025-04-01“…Furthermore, maleic acid was successfully detected in starch-rich dietary samples, including potatoes, sweet potatoes, and corn, utilizing the sensing capabilities of probes 4 and 5. …”
Get full text
Article -
1472
Estimation of some Organophosphorus Pesticides Using Carbon Paste Electrode Coupled with Molecularly Imprinted Polymers
Published 2018-09-01“…The method was validated and successfully applied to determined OPPs compounds from environmental water samples.…”
Get full text
Article -
1473
Soil microbial networks’ complexity as a primary driver of multifunctionality in photovoltaic power plants in the northwest region of China
Published 2025-04-01“…IntroductionExploiting photovoltaic power generation as a novel source of clean energy has become increasingly common in recent times. …”
Get full text
Article -
1474
The bacteriostatic regulation of luteolin from honeysuckle by protein network interaction
Published 2025-08-01“…Finally, the Molecular Complexity Detection (MCODE) algorithm and BinGo plugin were utilized to conduct module analysis and functional annotation of the constructed network, respectively. …”
Get full text
Article -
1475
Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates
Published 2025-05-01“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
Get full text
Article -
1476
Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§
Published 2025-01-01“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
Get full text
Article -
1477
MCM-41 based dispersive micro-solid phase extraction of selected cephalosporin antibiotic residues from water samples prior to liquid chromatographic quantification
Published 2024-12-01“…In this study, mesoporous silica (MCM-41) nanostructured material was synthesised and characterized by various analytical techniques to determine its morphology and dimension, functional groups, surface charge, and textural properties. …”
Get full text
Article -
1478
Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China
Published 2024-11-01“…Paddy fields are the main agricultural source of greenhouse gas methane (CH<sub>4</sub>) emissions. …”
Get full text
Article -
1479
Vitamin D Serum Levels and the Development of Intensive Care Unit-Acquired Weakness: Insights from a COVID-19 Intensive Care Cohort
Published 2025-05-01“…The exclusion criteria were a history of neurological or musculoskeletal disorders and a pre-existing poor functional status. Vitamin D was detected in the first routine blood sample. …”
Get full text
Article -
1480
Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case report
Published 2017-09-01“…The combination of pancreatic neuroendocrine tumors and serous cystic neoplasms is relatively rare, and the surgical treatment of these lesions must consider both preservation of pancreatic function and oncological clearance. We report a patient with von Hippel-Lindau disease successfully treated with pancreas-sparing resection of a pancreatic neuroendocrine tumor where the pancreas had been completely replaced by serous cystic neoplasms, in which pancreatic function was preserved. …”
Get full text
Article