Efficacy of minimally invasive vascular interventions assessed with mobile multispectral near-infrared spectroscopy by Alisha Roberta Oropallo, MD, Amit Rao, MD, Jo Ann Eisinger, PA, Larry Leonardi, PhD

“…By visualizing changes in microcirculation, this technology offers clinicians valuable insights, enabling earlier detection of treatment success or failure and facilitating timely interventions. …”
Get full text

Synthesis and Production of Sweet-Tasting Protein in E. coli and Purification by Amylose Resin by F. Mansouri

“…MBP-brazzein system permits large-scale functional expression and purification of recombinant soluble proteins, providing a basis for the future study of structure and function of brazzein.…”
Get full text

Multiwavelength Constraints on the Local Black Hole Occupation Fraction by Colin J. Burke, Priyamvada Natarajan, Vivienne F. Baldassare, Marla Geha

“…We also constrain the extremely low-luminosity end ( L _bol ≲ 10 ^40 erg s ^−1 ) of the active galactic nucleus (AGN) luminosity functions at z = 0. Our AGN luminosity functions are broadly consistent with an extrapolation of the shallow slope of the AGN luminosity functions from previous work.…”
Get full text

Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
Get full text

Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
Get full text

Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible by Qingge Guo, Xiuxiu Jin, Xiaoyu Xin, Xiaohong Guo, Shuai Ming, Yuxiang Li, Bo Lei

“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
Get full text

PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm by Naeem Shirmohammady, Habib Izadkhah, Ayaz Isazadeh

“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
Get full text

Presepsin as a sepsis biomarker by K. A. Trunova

“…The review includes 42 Russian-language and English-language  sources. Particular attention was paid to comparative studies on the role of presepsin and other bio-markers in the diagnosis of sepsis.Results. …”
Get full text

The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride. by Sabine Gruber, Susanne Zeilinger

“…Here we analyzed the functions of the T. atroviride Ste12 transcription factor whose orthologue in yeast is targeted by the Fus3 and Kss1 MAP kinases. …”
Get full text

Transcriptome analysis of corpora lutea in domestic cats (Felis catus) reveals strong differences in gene expression of various hormones, hormone receptors and regulators across di... by Beate C. Braun, Michał M. Hryciuk, Dorina Meneghini

“…Abstract In the domestic cat (Felis catus), the corpus luteum (CL) is the main source of progestogen during pregnancy. Here, we studied gene expression changes in different life cycle stages of the CL of pseudopregnant cats to identify potential regulatory factors. …”
Get full text

Neural Correlates of Changes in a Visual Search Task due to Cognitive Training in Seniors by Nele Wild-Wall, Michael Falkenstein, Patrick D. Gajewski

“…This study aimed to elucidate the underlying neural sources of near transfer after a multidomain cognitive training in older participants in a visual search task. …”
Get full text

A Gradient Grating Period Guided-Mode Resonance Spectrometer by Hsin-Yun Hsu, Yi-Hsuan Lan, Cheng-Sheng Huang

“…In this study, a GGP-GMR spectrometer less than 3 mm long that can achieve a wavelength detection range of 200 nm was demonstrated to reconstruct various incident spectra, including a single wavelength of light with a resolution of 0.5 nm, a single wavelength of light with varying intensity levels, and dual incident light sources.…”
Get full text

Evaluation of Adulticidal Clorine with Black Sand, White Sand and Silica Sand for Decline Coliform Bacteria by Rezania Asyfiradayati, Eni Budiyati, Mitoriana Porusia, Muhammad Rivandi Athaya, Afnan Zain Muzakki, Jenita Berlian Nindyasari, Siti Rohana Mohd Yatim

“…Methods: The study population comprised all water sources in the Pabelan Kartasura Sukoharjo Village area, with a total sample volume of 720 litres. …”
Get full text

Real-time monitoring of tea volatiles using soft ionization by chemical reaction in transfer with an online sampling interface by Tiange Gu, Jingyi Sun, Saiting Wang, Xiaokun Duan, Hongli Li, Charles Liu, David Da Yong Chen

Get full text

Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
Get full text

The influence of genetics on the endocannabinoid system gene expression and relevance for targeting reproductive conditions by Keisuke Tanaka, Akwasi A. Amoako, Sally Mortlock, Peter A. W. Rogers, Sarah J. Holdsworth-Carson, Jacqueline F. Donoghue, Wan Tinn Teh, Grant W. Montgomery, Brett McKinnon

“…Abstract Background Endocannabinoids are small lipid molecules that have critical roles in cellular proliferation and function. They are produced locally with their concentrations controlled via the endocannabinoid system (ECS). …”
Get full text

Empirical Therapy of Complicated Pyelonephritis by V. A. Beloborodov, V. A. Vorobev, P. V. Opanasyuk

“…Aminoglycosides showed the best result as a combination therapy with cephalosporins – 100 % (n = 3) of success. Based on multivariate logistic regression analysis, it was established that the detection of microhematuria and uremia in clinical analyzes upon admission to the hospital increases the likelihood of empirical monotherapy with third-generation cephalosporins by 20 % and 27 %, respectively.Conclusion. …”
Get full text

Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs by Sophie-Kristin Heinze, Jürgen Zentek, Kathrin Büttner, Andreas Moritz, Nadine Paßlack

“…An interaction effect between the dietary protein source and protein level could be detected for the phagocytic activity of blood granulocytes as well as for the plasma concentrations of IgA and IgE. …”
Get full text

An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts by Pascal Biermann, Claas Baier, Ann Christin Vietor, Benedikt Zacher, Tom Baumgartl, Tatiana von Landesberger, Michael Behnke, Michael Storck, Markus Petzold, Martin Kaase, HiGHmed lnfection Control Study Group, Dirk Schlüter, Michael Marschollek, Simone Scheithauer, Antje Wulff

“…Digital, routine data-driven solutions are promising, but often proprietary, non-interoperable, or limited in functional scope. The open-source Smart Infection Control System (SmICS) offers automatic calculations and interactive views on patients' movement and lab data, epidemic curves, contact networks, complemented by temporal-spatial visualizations. …”
Get full text

Development and evaluation of the remote passive integrated transponder tag reader for customizable monitoring of wildlife by Staci M. Amburgey, Aadithya Prakash, Amy A. Yackel Adams, Shane R. Siers, Sarah J. Converse

“…We evaluated differences in scanning success as a function of snake traits, location of PIT tags within snakes, and the distance of the PIT tag from the reader. …”
Get full text