Microarray-Based Comparisons of Ion Channel Expression Patterns: Human Keratinocytes to Reprogrammed hiPSCs to Differentiated Neuronal and Cardiac Progeny by Leonhard Linta, Marianne Stockmann, Qiong Lin, André Lechel, Christian Proepper, Tobias M. Boeckers, Alexander Kleger, Stefan Liebau

“…Numerous families of ion channels are present in the organism which can be distinguished by means of, for example, ion selectivity, gating mechanism, composition, or cell biological function. …”
Get full text

A Transition Metal‐Free Approach for the Conversion of Real‐Life Cellulose‐Based Biomass into Formate by Tong Zhang, Peng Ren, Yuman Qin, Thanh Huyen Vuong, Ana V. Cunha, Remco W. A. Havenith, Jabor Rabeah, Shoubhik Das

“…On the other hand, the world production of biomass is estimated at 146 billion metric tons per year and that can be considered as a prospective source of FA and their salts. Additionally, cellulose accounts for approximately 35–45% of the biomass composition. …”
Get full text

Mito Stress Assay of PBMCs With Seahorse XFe96 Flux Analyzer and Comparison of Poly-D-Lysine and Poly-L-Lysine for Cell Affinity by Kumudu Subasinghe, R. Berry III, Megan Rowe, Ali Winters, Shaohua Yang, Nicole Phillips

“…Recent studies have suggested that these cell populations provide an overview of systemic changes within the body and therefore provide a source of sensitive biomarkers. Assessing mitochondrial function in PBMCs has been shown to provide an indication of metabolic stress associated with diseases such as diabetes and neurodegenerative conditions such as Alzheimer’s disease. …”
Get full text

Decoupling of the onset of anharmonicity between a protein and its surface water around 200 K by Lirong Zheng, Bingxin Zhou, Banghao Wu, Yang Tan, Juan Huang, Madhusudan Tyagi, Victoria García Sakai, Takeshi Yamada, Hugh O'Neill, Qiu Zhang, Liang Hong

Get full text

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion by Xuhao Zhang, Yu Gao, Huiping Liao, Wenyan Wang, Zaili Yang, Weian Cao, Ge Li, Jing Wen, Gencheng Han, Yang-Xin Fu

“…Progressive loss of IL2-secretion is an early sign of diminished effector function in TILs, which raises the possibility of IL2 loss driving exhaustion of TILs. …”
Get full text

Differential efficacy of olfactory neurospheres from deviated nasal septum and chronic rhinosinusitis patients in regenerating olfactory epithelium by Rong-San Jiang, Chiang-Wen Lee, Yu-Hsuan Lin, Jing-Jie Wang, Jia-Bin Liao, Kuo-Ti Peng, Yao-Chang chiang, Pei-Ling Chi

“…Conclusions These findings highlight the importance of selecting the appropriate ONS source for therapeutic applications, with DNS-ONS showing greater promise for olfactory epithelium repair and olfactory function restoration.…”
Get full text

Multi-Omics Analysis Provides Insights into Green Soybean in Response to Cold Stress by Yanhui Lin, Guangping Cao, Jing Xu, Honglin Zhu, Liqiong Tang

“…The DEGs and DEMs were further subjected to KEGG functional analysis. Finally, 11 metabolites (such as sucrose, lactose, melibiose, and dehydroascorbate) and 17 genes (such as <i>GOLS</i>, <i>GLA</i>, <i>UGDH</i>, and <i>ALDH</i>) were selected as candidates associated with cold tolerance. …”
Get full text

Feature engineering for fault detection and diagnosis in Power Transmission Lines using a tree-based approach by Hassan N. Noura, Zaid Allal, Ola Salman, Khaled Chahine

“…The Power Transmission Line (PTL) is a pivotal infrastructure in the efficient distribution of electrical power, connecting the source generating stations to end-point consumers. …”
Get full text

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence by Changge Guan, Marcelo D. T. Torres, Sufen Li, Cesar de la Fuente-Nunez

“…From these, we identified 386 candidates that are structurally and functionally distinct from known antimicrobial peptides. …”
Get full text

Harnessing Hemp (<i>Cannabis sativa</i> L.) Seed Cake Proteins: From Concentrate Production to Enhanced Choux Pastry Quality by Tatiana Capcanari, Eugenia Covaliov, Cătălina Negoița

“…This study explores the production and valorization of hemp seed cake protein concentrate (HPC) as a functional ingredient to enhance the nutritional quality and sensory attributes of choux pastry products, specifically éclairs. …”
Get full text

Development of grain drink technology based on unsteamed buckwheat by G. M. Kerimova, I. A. Fomenko, A. R. Pivchenko, I. R. Sokolov

“…The aim of the research is to select the parameters  for the production of a grain drink. …”
Get full text

Application of artificial intelligence in echocardiography from 2009 to 2024: a bibliometric analysis by Yangli Liu, Lei Zhao, Bin Tu, Jie Wang, Yaqun He, Rufang Jiang, Xiaofeng Wu, Wen Wen, Jian Liu

“…The objective of this study is to explore the current status and prevailing research trends in this field from 2009 to 2024 through bibliometric analysis and to forecast future developmental trajectories.MethodsWe selected the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WOSCC) as our primary data source and conducted a comprehensive search encompassing all articles and reviews published between 2009 and 2024 and used the online analysis platform of bibliometrics, CiteSpace and VOSviewer software to analyze countries/regions, institutions, authors, keywords, and references, used Microsoft Excel 2021 to visualize the trends of the number of articles published by year.ResultsBetween 2009 and 2024, a total of 3,411 publications on AI applications in echocardiography were identified, including 3,000 articles (87.9%) and 411 reviews (12.1%), contributed by researchers from 100 countries/regions. …”
Get full text

The evolution and competitive strategies of Akkermansia muciniphila in gut by Ji-Sun Kim, Se Won Kang, Ju Huck Lee, Seung-Hwan Park, Jung-Sook Lee

“…In addition, WapA and anSME, which function in competition and post-translational modification of sulfatase, respectively, have been a particularly important selective pressure in the evolution of group A. …”
Get full text

Influence of suturing material on wound healing: Experimental study in dogs by Gazivoda Dragan, Pelemiš Dejan, Vujašković Goran, Đurđević Slaviša

“…When using resorbable materials it is of great importance to determine whether its absorbability and tensile strength help wound healing in function of time. Sutures themselves can become a source of inflammation, that may reduce or compromise the potential of reparation and regeneration. …”
Get full text

Enhancing the socio-cultural valuation of ecosystem services in Mountain animal production: a case study from piedmont’s alpine valley (North-west Italy) by Chiara Costamagna, Valentina Maria Merlino, Danielle Borra, Lorenzo Baima, Paolo Cornale, Luca Maria Battaglini

“…The new principal components were employed to cluster the sample in the function of individuals’ perceptions of ecosystem services. …”
Get full text

Staged approach to bilateral severe carotid stenosis: a case report and literature review by Heitor Cabral Frade, Manmeet Kaur, Julia Aigbogun, Muhammad Zeeshan Memon, Arun Chhabra, Akm Muktadir, Hashem Shaltoni

“…Hyperperfusion syndrome (HPS), with or without associated intracerebral hemorrhage, although rare, is a major source of morbidity and mortality after carotid interventions, especially in the setting of bilateral CAD. …”
Get full text

Efficacy of Anti-VEGF/VEGFR Agents on Animal Models of Endometriosis: A Systematic Review and Meta-Analysis. by Shuangge Liu, Xiaoyan Xin, Teng Hua, Rui Shi, Shuqi Chi, Zhishan Jin, Hongbo Wang

“…Subgroup analyses were performed to determine the source of heterogeneity in endometriosis scores and follicle numbers.…”
Get full text

Mapping and Spatial Analysis of the Development of the Administrative Borders of Stavropol Region in 1785–2021 by Igor Yurievich Katorgin, Alexander Nikolaevich Roman

“…Geoinformation technologies allow processing, spatial coordination of digitized old maps with optimal accuracy, creation of thematic layers necessary for spatial analysis and visualization of the results of work in the form of a series of maps displaying the ATD of the Stavropol region for different periods of development history.Materials and research methods. As the main source of spatial data, old maps were used, selected according to 12 stages of the development of the Stavropol region ATD system over a 237-year period. …”
Get full text

Insights on comprehensive characterization of distinct growth stages of Sterculia foetida pod as a potential feedstock for bioethanol production by Saroja Pasupathi, Sameeha Syed Abdul Rahman, Sugumaran Karuppiah

“…Abstract Lignocellulosic biomass explores a sustainable and renewable energy source that could provide a suitable solution to energy demands. …”
Get full text

A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity. by Andrew P Holmes, Ting Y Yu, Samantha Tull, Fahima Syeda, Stefan M Kuhlmann, Sian-Marie O'Brien, Pushpa Patel, Keith L Brain, Davor Pavlovic, Nigel A Brown, Larissa Fabritz, Paulus Kirchhof

“…<h4>Methods</h4>We used high-resolution optical mapping and sharp microelectrode recordings to quantify regional differences in electrical activation and repolarisation within the intact, superfused murine left atrium and quantified regional ion channel mRNA expression by Taqman Low Density Array. We also performed selected cellular electrophysiology experiments to validate regional differences in ion channel function.…”
Get full text