Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals by Edanur Güler–Ekmen, İsmail Çağrı Yılmaz, Talat Güler, Derya Güler, Mehtap Özçelik

“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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Substandard Language Phenomena in Artistic Discourse by Anzhelika V. Korolkova, Tatyana S. Novikova

“…The substandard is currently becoming a source of replenishment of the stylistically reduced layer of modern colloquial speech.…”
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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection. by Alex J McCarthy, David Negus, Patricia Martin, Catarina Pechincha, Eric Oswald, Richard A Stabler, Peter W Taylor

“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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Controllable surface carrier type of metal oxide nanocrystals for multifunctional photocatalysis by Han Li, Yingchun Ding, Kaiyi Luo, Qiuping Zhang, Huan Yuan, Shuyan Xu, Ming Xu

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TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion by Xuhao Zhang, Yu Gao, Huiping Liao, Wenyan Wang, Zaili Yang, Weian Cao, Ge Li, Jing Wen, Gencheng Han, Yang-Xin Fu

“…Progressive loss of IL2-secretion is an early sign of diminished effector function in TILs, which raises the possibility of IL2 loss driving exhaustion of TILs. …”
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Differential efficacy of olfactory neurospheres from deviated nasal septum and chronic rhinosinusitis patients in regenerating olfactory epithelium by Rong-San Jiang, Chiang-Wen Lee, Yu-Hsuan Lin, Jing-Jie Wang, Jia-Bin Liao, Kuo-Ti Peng, Yao-Chang chiang, Pei-Ling Chi

“…Conclusions These findings highlight the importance of selecting the appropriate ONS source for therapeutic applications, with DNS-ONS showing greater promise for olfactory epithelium repair and olfactory function restoration.…”
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Multi-Omics Analysis Provides Insights into Green Soybean in Response to Cold Stress by Yanhui Lin, Guangping Cao, Jing Xu, Honglin Zhu, Liqiong Tang

“…The DEGs and DEMs were further subjected to KEGG functional analysis. Finally, 11 metabolites (such as sucrose, lactose, melibiose, and dehydroascorbate) and 17 genes (such as <i>GOLS</i>, <i>GLA</i>, <i>UGDH</i>, and <i>ALDH</i>) were selected as candidates associated with cold tolerance. …”
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Microalgal Metabolomes and Recent Biotechnological Advances for Their Industrial Application by Dinesh Kumar Saini, Geetanjali Manchanda, Ratiram Gomaji Chaudhary, Raghvendra Pratap Singh

“…These organisms are photosynthetic, use CO₂ as their sole carbon source, and grow rapidly under different environmental conditions. …”
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Biomarkers associated with cell-in-cell structure in kidney renal clear cell carcinoma based on transcriptome sequencing by Zehua Wang, Zhongxiao Zhang

“…Methods Data for this study were sourced from The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), and Gene Expression Omnibus (GEO) databases. …”
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Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically... by Nessrin Alomran, Jaffer Alsolaiss, Laura-Oana Albulescu, Edouard Crittenden, Robert A Harrison, Stuart Ainsworth, Nicholas R Casewell

“…Two different immunogen mixtures, consisting of seven and twelve haemotoxic venoms sourced from geographically diverse and/or medically important snakes, were used to raise ovine polyclonal antibodies, prior to characterisation of their immunological binding characteristics and in vitro neutralisation profiles against each of the venoms. …”
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Bioactive Compounds and Antioxidant Activity of <i>Boletus edulis</i>, <i>Imleria badia</i>, <i>Leccinum scabrum</i> in the Context of Environmental Conditions and Heavy Metals Bio... by Zofia Sotek, Katarzyna Malinowska, Małgorzata Stasińska, Ireneusz Ochmian

“…From a practical perspective, the results highlight the importance of species selection and sourcing location when considering wild mushrooms for consumption or processing, particularly in the context of nutritional value and contaminant load. …”
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Investigation of the Application of Machine Learning Algorithms in Credit Risk Assessment of Medium and Micro Enterprises by Yujie Zhao

“…Thus, this proposed method achieves 14.65% high-risk detection with 5.56% financial revisions for the industry considered by the data source.…”
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Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…ConclusionsIn clinical practice, our tool would enable the automated monitoring and detection of risk points throughout all clinical trial stages; accurately identify the most relevant trial procedure and function line; and notify quality management personnel, in real time, to take prompt actions and dynamically prevent the recurrence of quality issues.…”
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Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence by Changge Guan, Marcelo D. T. Torres, Sufen Li, Cesar de la Fuente-Nunez

“…From these, we identified 386 candidates that are structurally and functionally distinct from known antimicrobial peptides. …”
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Learning Transferable Convolutional Proxy by SMI-Based Matching Technique by Wei Jin, Nan Jia

“…The classification responses are also smoothened by manifolds of both the source domain and proxy space. By minimizing an objective function of SMI, classification error, and manifold regularization, we learn the convolutional networks of both source and target domains. …”
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Vitamin D and Osteoporosis in HIV/HCV Coinfected Patients: A Literature Review by Paola Di Carlo, Lucia Siracusa, Giovanni Mazzola, Piero Colletti, Maurizio Soresi, Lydia Giannitrapani, Valentina Li Vecchi, Giuseppe Montalto

“…The final 12 articles selected are homogeneous in terms of age but heterogeneous in terms of sample size, participant recruitment, and data source. …”
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Harnessing Hemp (<i>Cannabis sativa</i> L.) Seed Cake Proteins: From Concentrate Production to Enhanced Choux Pastry Quality by Tatiana Capcanari, Eugenia Covaliov, Cătălina Negoița

“…This study explores the production and valorization of hemp seed cake protein concentrate (HPC) as a functional ingredient to enhance the nutritional quality and sensory attributes of choux pastry products, specifically éclairs. …”
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Application of artificial intelligence in echocardiography from 2009 to 2024: a bibliometric analysis by Yangli Liu, Lei Zhao, Bin Tu, Jie Wang, Yaqun He, Rufang Jiang, Xiaofeng Wu, Wen Wen, Jian Liu

“…The objective of this study is to explore the current status and prevailing research trends in this field from 2009 to 2024 through bibliometric analysis and to forecast future developmental trajectories.MethodsWe selected the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WOSCC) as our primary data source and conducted a comprehensive search encompassing all articles and reviews published between 2009 and 2024 and used the online analysis platform of bibliometrics, CiteSpace and VOSviewer software to analyze countries/regions, institutions, authors, keywords, and references, used Microsoft Excel 2021 to visualize the trends of the number of articles published by year.ResultsBetween 2009 and 2024, a total of 3,411 publications on AI applications in echocardiography were identified, including 3,000 articles (87.9%) and 411 reviews (12.1%), contributed by researchers from 100 countries/regions. …”
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