Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Work package 4: Development and refinement of a care transitions intervention Intervention development Functional resonance analysis method was used to model the transition process. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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Joint analysis of single-cell RNA sequencing and bulk transcriptome reveals the heterogeneity of the urea cycle of astrocytes in glioblastoma by Minfeng Tong, Qi Tu, Lude Wang, Huahui Chen, Xing Wan, Zhijian Xu

“…GB-mRNA expression data, clinical data, and SNV mutation data were sourced from the Cancer Genome Atlas (TCGA). GB-mRNA expression data and clinical data were downloaded from the Chinese Glioma Genome Atlas (CGGA). …”
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Development and validation of liquid–liquid phase separation-associated prognostic biomarkers in gastric cancer by Donghui Liu, Mingzhu Liu, Juan Du

“…Abstract Objective Liquid–liquid phase separation (LLPS) is the membrane-less formation of functional assemblies from specific molecules. It plays a key role in tumor growth by governing gene expression. …”
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Regularities of the Natural Evolution of the Proliferative Process in Diabetic Retinopathy. The Concept of Remission of Proliferative Diabetic Retinopathy by S. V. Sdobnikova

“…Therefore, the scale reflecting the stages of evolution of newly formed vessels and the scale of severity reflecting the degree of threat to visual functions in PDR cannot be identical. Since the development and regression of neovessels is a reflection of multidirectional processes, the identification of the phase of PDR evolution is fundamental in the formation of research design. …”
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Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer’s Disease Diagnosis by Maria João Oliveira, Pedro Ribeiro, Pedro Miguel Rodrigues

“…<i>MCI</i>, the proposed model outperformed state-of-the-art imaging source studies by 0.1% and non-imaging source studies by 4.6%. …”
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Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3 by Lisa Morand-Laffargue, Florence Charles, Charlotte Sabran, Patrick Borel

“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria by Nirasha Atapattu, Nicolas Justus, Hariniha Selvarajan, Mitzchilouise Baylosis, Marc Schieven, Kalindi D. Morgan

“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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Regional and strain-level prevalence of nitrogen-fixing Bradyrhizobium with potential N2O reduction in South Korea by Jaeyoung Ro, Hor-Gil Hur, Sujin Lee

“…Abstract Agricultural practices are the largest anthropogenic source of nitrous oxide (N2O), a potent greenhouse gas contributing to global climate change. …”
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Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution. by John K Pace, Shurjo K Sen, Mark A Batzer, Cédric Feschotte

“…This mechanism has duplicated hundreds of sequences predicted to be functional in the human genome, including exons, UTRs, intron splice sites and transcription factor binding sites. …”
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Devicology: Expanding fieldwork possibilities for architectural observations in inhabited interiors by Tatiana Knoroz

“…These visually chaotic yet surprisingly functional structures are the only tool of the current dwellers to negotiate with the restricting standard apartment plans that were originally designed for a very different sector of the Japanese population. …”
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A survey on the applications of transfer learning to enhance the performance of large language models in healthcare systems by Anmol Rahujo, Daniya Atif, Syed Azeem Inam, Abdullah Ayub Khan, Sajid Ullah

“…This research analyzes different transfer learning methods, including inductive, transductive, and unsupervised techniques, while demonstrating their effectiveness in detecting COVID-19 from chest X-rays and multi-source disease evaluation. …”
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Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability by Huangzhe Dai, Chengqian Zhang, Hao Hu, Zhezai Hu, Haonan Sun, Kan Liu, Tiefeng Li, Jianzhong Fu, Peng Zhao, Huayong Yang

“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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Current status of transcriptome sequencing technology in ruminants by Cui JiaYu, Song Lili, Wang Dawei, Liu ZhiLin, Zhang Xin, Jia Zelin, Zhang Yuhang, Xiong Huisheng, Wang Xueli

“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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User Communities — Drivers for Open Innovation by Gunnar Prause, Thomas Thurner

“…Users best judge what will lead to commercial success, and they have long been recognized as a valuable source of knowledge to harvest for future innovation. …”
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Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

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Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques by Renata F. Leoni, Kelley C. Mazzetto-Betti, Afonso C. Silva, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto

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Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…In conclusion, our results provide the immune landscape of necrotizing granulomas and reveal novel functional states of macrophages contributing to TB pathogenesis.…”
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Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh by Sharmin Sultana, Md Shamsuzzaman, Md. Abdus Satter Miah, Akhter Jahan Kakon, Abdullah Hel Mafi, Anupoma Sen, Md. Nurealam Siddiqui, Debu Kumar Bhattacharjya

“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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