Joint analysis of single-cell RNA sequencing and bulk transcriptome reveals the heterogeneity of the urea cycle of astrocytes in glioblastoma by Minfeng Tong, Qi Tu, Lude Wang, Huahui Chen, Xing Wan, Zhijian Xu

“…GB-mRNA expression data, clinical data, and SNV mutation data were sourced from the Cancer Genome Atlas (TCGA). GB-mRNA expression data and clinical data were downloaded from the Chinese Glioma Genome Atlas (CGGA). …”
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Characterization of all life stages of Tenebrio molitor: Envisioning innovative applications for this edible insect by Nuno Muñoz-Seijas, Helena Fernandes, José Eugenio López-Periago, David Outeiriño, María Guadalupe Morán-Aguilar, José Manuel Domínguez, José Manuel Salgado

“…The human food security is unavoidably dependent on exploring novel nutritional sources, such as edible insects. However, insects farming needs to improve their rearing practices, such as extracting value from all growing stages, from larvae until adults. …”
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Research progress on in-situ catalytic hydrodeoxygenation of lignin by ZHAO Yuying, ZHAN Jiahui, HU Rui, LUO Gang, ZHANG Shicheng*

“…It utilizes solvents or lignin′s functional groups as hydrogen sources. During the catalytic process, hydrogen is generated in situ and acts on the substrate, achieving efficient value-added conversion. …”
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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer by Qing Wang, Maha Ayyoub, Olivia Le Saux, Paola Bonaventura, Isabelle Treilleux, Nicolas Chopin, Clarisse Dubois, Virginie Mutez, Nicolas Chuvin, Yann Estornes, Jenny Valladeau-Guilemond, Stephane Depil, Nicolas Gadot, Marie Michelas, Audrey Page, Olivier Tabone, Marie Delles, Sarah Moran, Thibault Richard, Marjorie Lacourrège, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez

“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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Transforming Bone Tunnel Evaluation in Anterior Cruciate Ligament Reconstruction: Introducing a Novel Deep Learning System and the TB-Seg Dataset by Ke Xie, Mingqian Yu, Jeremy Ho-Pak Liu, Qixiang Ma, Limin Zou, Gene Chi-Wai Man, Jiankun Xu, Patrick Shu-Hang Yung, Zheng Li, Michael Tim-Yun Ong

“…Evaluating bone tunnels is crucial for assessing functional recovery after anterior cruciate ligament reconstruction. …”
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Decellularized Matrix Scaffolds for Vascular Transplantation: Addressing Immunogenicity, Sterilization, and Current Strategies for Long-Term Storage by Yevhen V. Shevchenko, Tetiana I. Liadova, Fedir V. Hladkykh, Mariia S. Matvieienko, Mykola O. Chyzh, Roman R. Komorovsky

“…To conduct a comparative analysis of sterilization methods for decellularized matrix scaffolds used in vascular transplantation, based on information from open sources. Materials and methods. Publications were selected from the databases PubMed, Clinical Key Elsevier, Cochrane Library, eBook Business Collection, and Google Scholar, focusing on sterilization methods for decellularized matrix scaffolds. …”
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Antioxidant and Anti-Inflammatory Activities of Cutlassfish Head Peptone in RAW 264.7 Macrophages by Su-Jin Lee, Jeonghyeon Im, Svini Dileepa Marasinghe, Eunyoung Jo, Minthari Sakethanika Bandara, Youngdeuk Lee, Jaewon Lee, Gun-Hoo Park, Chulhong Oh

“…Recent advances in valorization techniques have highlighted the potential of these by-products as sources of bioactive compounds. This study aimed to investigate the antioxidant and anti-inflammatory activities of cutlassfish <i>(Trichiurus lepturus)</i> head peptone (CP) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. …”
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Senegalin-2: A Novel Hexadecapeptide from <i>Kassina senegalensis</i> with Antibacterial and Muscle Relaxant Activities, and Its Derivative Senegalin-2BK as a Bradykinin Antagonist by Yueyang Lu, Yanguo Zhu, Chengbang Ma, Lei Wang, Mei Zhou, Tianbao Chen, Xiaonan Ma, Xu Zhang, Zhimin Fan

“…The amphibian skin secretions are excellent sources of bioactive peptides, some of which and their derivatives exhibit multiple properties, including antibacterial and antagonism against bradykinin. …”
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Fast-timing spectroscopy with the ν-ball2 spectrometer by Pascu S., Hiver C., Podolyák Zs., Regan P.H., von Tresckow M., Wilson J.N.

“…These observables and their corresponding transition probabilities are key fingerprints for the structure of atomic nuclei, as they are sensitive to small components of the wave function. Neutron-rich nuclei have been populated in a two-step fission-induced experiment. …”
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Simple fuzzy classification of metal qualities of Ona River, Ibadan, Nigeria, and its implication for fish production and other uses by Olayiwola Akin Akintola, Foluso Oyedotun Agunbiade, Tolulope Omolayo Ariyomo, Toju Esther Babalola, Bolaji Adelanke Adabembe, Oluwaseun Temitope Faloye, Opeyemi Samuel Sajo

“…The results revealed that the PTEs: Fe, Pb, Cd, Cr, and Mn were detected above guideline limits in several sampling points, indicating possible contamination from anthropogenic sources. …”
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A Comprehensive Study on the Nutritional Profile and Shelf Life of a Custom-Formulated Protein Bar Versus a Market-Standard Product by Corina Duda-Seiman, Liliana Mititelu-Tartau, Simona Biriescu, Alexandra-Loredana Almășan, Bianca-Oana Bitu, Adina-Ioana Bucur, Andrei Luca, Bogdan Hoinoiu, Teodora Hoinoiu

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Electrochemical Magnetic Immunoassay for the Determination of the Fish Allergen β-Parvalbumin by José Pedro Rocha, Maria Freitas, Dulce Geraldo, Fátima Bento, Cristina Delerue-Matos, Henri P. A. Nouws

“…A linear concentration range from 10 to 1000 ng/mL, a limit of detection of 1.8 ng/mL, and a limit of quantification of 7.1 ng/mL were achieved. …”
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The association of internet use and cognition among older adults: mediating roles of social networks and depressive symptoms by Xiuyuan Zhu, Zihan Ni, Xiaoying Zhu, Xiaoying Zhu, Yi Yang, Shiyu Xie, Xinguo Wang, Xiaoguang Yang

“…BackgroundTo explore the chain-mediated roles of social networks and depressive symptoms in the relationship between internet use and cognition among older adults.MethodsData were sourced from the 2018 China Longitudinal Aging Social Survey (CLASS). …”
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The Impact of Audit Quality on Organizational Capital and Financing Capacity by Somaye Fathi, Mahdi Bahar Moghadam, Kazem Shamsadini

“…Metod and dataThis study employs panel data analysis of 1,776 firm-year observations (148 companies) from Tehran Stock Exchange-listed firms between 2011-2022, sourced from the Codal database and the Management Research, Development, and Islamic Studies Library. …”
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Ageing well in the urban environment: meeting the health and social needs of older Adults - study protocol for a prospective, longitudinal mixed-methods study by Marie Bolster, Abhijit Visaria, David Matchar, Denis Gerstorf, Tillman Schmitz, Benjamin Labohm, Raphael Kohl, Dagmar Haase, Paul Gellert, Angelique Chan, Wolfram J. Herrmann

“…Additionally, three functional tests (cognitive functioning, hand grip strength, and walking speed) are carried out with participants. …”
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Optimizing processing methods for maximum bioactive retention: comparative metabolomic analysis of dried loquat (Eriobotrya japonica) flowers and their powdered extracts by Mingzheng Duan, Jieming Feng, Jing-Han Feng, Xi Wang, Xu Xiao, Shirong He, Hengcui Guo, Wenyan Zhang, Zhumao Jiang, Tongfa Wan, Muhammad Junaid Rao

“…The results demonstrate that freeze-drying optimizes flavonoid retention, making it ideal for high-quality nutraceuticals, while heat-drying may suit cost-effective production of select heat-stable compounds. These insights guide the development of standardized loquat flower products, balancing bioactive preservation with processing efficiency for functional food and herbal medicine applications.…”
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A Study on the Influence Mechanisms of Neighborhood Vitality and the Characteristics of Spatial and Temporal Differentiation in the Urban Fringe Areas of Wuhan City by Yan Long, Siyu Hu, Zhengyuan Lu, Lianghao Cheng, Cairui Zhen, Jingmei Shao, Yuqiao Zheng, Xuehui Zhou, Jin Li, Yudi Lin, Shu Zhang, Yue Wang, Tianyue Luo, Haijuan Zhao, Xuejun Liu

“…This paper quantifies the neighborhood vitality of the fringe areas by the short-stay visitors in the fringe areas and selects the 5D elements of the built environment and social media data from multiple sources to construct the indicator system assessing the neighborhood vitality of the urban fringe areas. …”
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Fe foam supported FeVO4 nanoparticles for electrochemical nitrogen fixation at ambient conditions by Abdulmalik Aminu, Bilal Masood Pirzada, Shamraiz Hussain Talib, Janah Shaya, Ibrahim Yildiz, Sharmarke Mohamed, Ahsanulhaq Qurashi

“…As global energy demand continues to rise with fossil fuels dwindling at a faster rate, posing energy and environmental concerns, there is a growing interest in exploring alternative, green, and renewable energy sources. Ammonia is a key hydrogen energy carrier and precursor to many value-added products, and the efforts for its generation at commercial scale using greener methods are intensifying to mitigate the reliance on the energy-intensive Haber-Bosch process. …”
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Feedback of patient-reported outcomes to healthcare professionals for comparing health service performance: a scoping review by Dominique A Cadilhac, Shaun L Hancock, Olivia F Ryan, Violet Marion, Sharon Kramer, Paulette Kelly, Sibilah Breen

“…Therefore, the aim of this scoping review was to summarise the emerging approaches to PROs data for ‘service-level’ feedback to healthcare professionals.Setting Healthcare professionals receiving PROs data feedback at the health-service level.Data sources Databases selected for the search were Embase, Ovid Medline, Scopus, Web of Science and targeted web searching. …”
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Thermophilic microbial agents promote the fermentation progression of spent mushroom compost and pig manure by Hongbo Du, Chongchong Lu, Muhanmad Zunair Latif, Jianfeng Du, Yong Liu, Hongxin Li, Xinhua Ding

“…Overall, the application of thermophilic microbial agents not only extended the high temperature phase of composting by over 30% and shortened the composting cycle by 50%, but more importantly, it achieved comprehensive improvement in compost quality by selectively enriching functional microbial communities such as Pseudomonas. …”
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