A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…We also show that apicalized Punt does not produce an ectopic signal, indicating that the apical pool of Dpp is not a significant signaling source even when presented with Punt. Instead, we find that basolateral presentation of Punt is required for optimal signaling. …”
Get full text

Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
Get full text

Canada goose fecal microbiota correlate with geography more than host‐associated factors by Joshua C. Gil, Heather R. Skeen, Celeste Cuellar, Sarah M. Hird

“…This work also suggests that there is a minimum geographic distance, likely associated with sufficient variation in habitat, climate, and local food sources, that must be reached before significant differences in the microbiota between two populations can be detected.…”
Get full text

Synthesis of Molecularly Imprinted Polymers for Selective Extraction Followed by Solid Phase Determination of Metformin in Pharmaceutical Preparation and in Human Serum by Rana A. Kamal Aldeen, Yehya K. Al-Bayati

“…A solid-phase extraction (SPE) syringe packed with molecular imprinted polymers (MIPs) was employed to selectively separate and pre-concentrate the Metformin in multiple pharmaceutical drugs from several sources. The human serum was based on the use of deionized water to dilute the serum, followed by the heating of the serum with methanol. …”
Get full text

Strain Monitoring of Vertical Axis Wind Turbine Tower Using Fiber Bragg Gratings by Bastien Van Esbeen, Valentin Manto, Damien Kinet, Corentin Guyot, Christophe Caucheteur

“…Afterwards, by using power spectral density (PSD) on the strain signals, three sources of tower oscillations are discovered: wind force, structure unbalance, and 1st tower mode resonance, each with its intrinsic frequency. …”
Get full text

Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
Get full text

Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
Get full text

Identification and odor exposure regulation of odorant-binding proteins in Picromerus lewisi by Shan-Cheng Yi, Jia-Ling Yu, Sara Taha Abdelkhalek, Sara Taha Abdelkhalek, Zhi-Rong Sun, Man-Qun Wang

“…This implies that these PlewOBPs may have an olfactory function in detecting S. litura-infested tobacco plants. …”
Get full text

Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria by Nirasha Atapattu, Nicolas Justus, Hariniha Selvarajan, Mitzchilouise Baylosis, Marc Schieven, Kalindi D. Morgan

“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
Get full text

The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
Get full text

Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
Get full text

Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability by Huangzhe Dai, Chengqian Zhang, Hao Hu, Zhezai Hu, Haonan Sun, Kan Liu, Tiefeng Li, Jianzhong Fu, Peng Zhao, Huayong Yang

“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
Get full text

Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
Get full text

Characterization of all life stages of Tenebrio molitor: Envisioning innovative applications for this edible insect by Nuno Muñoz-Seijas, Helena Fernandes, José Eugenio López-Periago, David Outeiriño, María Guadalupe Morán-Aguilar, José Manuel Domínguez, José Manuel Salgado

“…The human food security is unavoidably dependent on exploring novel nutritional sources, such as edible insects. However, insects farming needs to improve their rearing practices, such as extracting value from all growing stages, from larvae until adults. …”
Get full text

Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media by Humaira Yasmin, Rawan Bossly, Fuad S. Alduais, Afrah Al-Bossly, Anwar Saeed

“…The greater magnetic, Brownian motion, heat source, thermal radiation factors, and thermophoresis factors have increased the heat transfer rate. …”
Get full text

Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…A subset of the Plin2-expressing macrophages was identified as a major source of Ifnb1 and Cxcl1, suggesting their involvement in type I interferon signaling and neutrophil recruitment. …”
Get full text

Artificial intelligence and radiomics applications in adrenal lesions: a systematic review by Matteo Ferro, Octavian Sabin Tataru, Giuseppe Carrieri, Gian Maria Busetto, Ugo Giovanni Falagario, Martina Maggi, Felice Crocetto, Biagio Barone, Francesco Del Giudice, Michele Marchioni, Daniela Terracciano, Giuseppe Lucarelli, Pasquale Ditonno, Raul Gherasim, Ciprian Todea-Moga, Giuseppe Fallara, Marco Tozzi, Antonio Cioffi, Roberto Bianchi, Alessio Digiacomo, Alessandro Veccia, Alessandro Antonelli, Maria Chiara Sighinolfi, Luigi Schips, Bernardo Rocco

“…Background: Adrenal lesions, often incidentally detected, present diagnostic challenges in distinguishing benign from malignant or hormonally active lesions. …”
Get full text

Performance of the HAWC Observatory and TeV Gamma-Ray Measurements of the Crab Nebula with Improved Extensive Air Shower Reconstruction Algorithms by A. Albert, R. Alfaro, C. Alvarez, A. Andrés, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K. S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, C. de León, D. Depaoli, N. Di Lalla, R. Díaz Hernández, B. L. Dingus, M. A. DuVernois, K. Engel, T. Ergin, C. Espinoza, K. L. Fan, K. Fang, N. Fraija, S. Fraija, J. A. García-González, F. Garfias, H. Goksu, M. M. González, J. A. Goodman, S. Groetsch, J. P. Harding, S. Hernández-Cadena, I. Herzog, J. Hinton, D. Huang, F. Hueyotl-Zahuantitla, P. Hüntemeyer, A. Iriarte, S. Kaufmann, A. Lara, J. Lee, H. León Vargas, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, J. Martínez-Castro, J. A. Matthews, P. Miranda-Romagnoli, J. A. Montes, E. Moreno, M. Mostafá, L. Nellen, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, M. Osorio-Archila, Y. Pérez Araujo, E. G. Pérez-Pérez, C. D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, G. Schwefer, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, X. Wang, I. J. Watson, K. Whitaker, E. Willox, H. Wu, S. Yu, S. Yun-Cárcamo, H. Zhou, HAWC Collaboration

“…Thanks to these improvements, HAWC can now detect more sources, including the Galactic center.…”
Get full text

Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05 by Randa Harrat, Ghania Bourzama, Gaëtan Burgaud, Emmanuel Coton, Aymen Bourezgui, Boudjema Soumati

“…SEM analysis revealed morphological alterations, including cracks and holes, ATR-FTIR detected new functional groups (alcohols, alkynes, aldehydes, alkenes and ketones), while XRD identified changes in the polymer crystallinity and phase composition. …”
Get full text

Preliminary Study on Natural Infection of Shellfish with Movement Disorder Nodavirus (MDNV) by Ping LI, Jitao XIA, Changming BAI, Ruidong XU, Tingting XU, Shuang LIU, Liang YAO, Xingtong YU, Qingli ZHANG

“…Shellfish is an important source of high-quality protein for human beings and simultaneously plays an important ecological service function in the marine ecosystem. …”
Get full text