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1861
Transcription Factor LjWRKY50 Affects Jasmonate-Regulated Floral Bud Duration in <i>Lonicera japonica</i>
Published 2025-07-01“…<i>Lonicera japonica</i> Thunb. is a traditional Chinese medicinal herb whose floral buds are the primary source of pharmacological compounds that require manual harvesting. …”
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1862
Identification and characterization of the powdery mildew resistance in cultivated emmer wheat accession Lxd-682 via bulked segregant RNA sequencing
Published 2025-05-01“…Molecular markers JS717/JS718 and WGRC1096 were confirmed to be available for marker-assisted selection (MAS) of PmLxd-682 in breeding practices. …”
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1863
BDNF Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults
Published 2025-04-01“…In moderated mediation analyses examining cognitive outcomes, plasma p‐tau181 selectively mediated the relationship between PA and executive function in Val/Val participants. …”
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1864
Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area
Published 2025-03-01“…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
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1865
Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility
Published 2025-02-01“…Abstract Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. …”
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1866
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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1867
Evaluating Factors Affecting Interior Architectural Space Quality to Enhance Spatial Resilience and Human Productivity: An Application of Maslow’s Hierarchy of Needs
Published 2025-06-01“…</p> <p style="text-align: left;"><strong>Methodology.3</strong></p> <p style="text-align: left;">In the present study, the data and information was collected through document analysis, in-depth semi-structured interviews and formation of a focus group. The sample selection was done using snowball sampling method. …”
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1868
iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health
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1869
Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review
Published 2025-05-01“…Secondary outcomes: clinical-/patient-reported outcomes. Data sources Seven primary studies databases; Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, Health Technology Assessment Database and Trial Registers to 31 August 2023. …”
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1870
The Challenges of Safety Culture: No more risk!
Published 2016-12-01“…These factors by themselves are the definite source of disaster. People are not able to avoid their impacts: different crashes, accidents, fires. …”
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1871
Demand and Influencing factors for community health services during chemotherapy of patients with advanced cancer
Published 2024-06-01“…Logistic regression analysis showed that educational level and disposable monthly household income significantly influenced psychological demand, while age and source of medical expenses influenced medical care demand, and age and patient group participation affected social support demand (P < 0.05). …”
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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c...
Published 2025-02-01“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. The m6aCRLncs linked to EC were identified through co-expression analysis. …”
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1873
Targeting hyperlipidemia: A polarity-driven ternary extraction of Apium graveolens bioactives—A coupled in-vivo, in-vitro and in-silico investigation
Published 2025-08-01“…The findings of the in-silico studies revealed that the 3 top performing compounds (i.e. apiumoside, apiin and graveobioside B) showed high binding affinity to selected anti hyperlipidemic targets HMG CoA reductase and peroxisome proliferator-activated receptor-Alpha (PPAR-Alpha) with a very stable condition in the molecular dynamic simulation against the selected targets. …”
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1874
Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement
Published 2024-11-01“…Spider venom‐derived peptide toxins are recognized as significant sources of Nav1.7 inhibitors. However, their development has been impeded by limited selectivity. …”
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1875
Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification
Published 2025-01-01“…Homo- or heterodimeric compounds that affect dimeric protein function through interaction between monomeric moieties and protein subunits can serve as valuable sources of potent and selective drug candidates. …”
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1876
Comparison of Fuzzy-AHP and ANP Decision Making Methods to Assess the Ecological Capability of Ecotourism Application (Case study: Dehloran National Natural Monuments)
Published 2018-11-01“…Then, to combine the layers, the model of overlapping index or linear weight composition was used. 3-Results and Discussion Using the GIS on the slope of the linear reduction subscription function, the trajectory linear membership function layer and the temperature layer, an incremental linear membership function was applied. …”
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1877
Effects of exogenous sugars on root sugar metabolism and antioxidant system under sub-low root-zone temperature in Malus baccata Borkh.
Published 2025-07-01“…And, sugar not only serves as structural material and an energy source but also has signaling functions to regulate the expression of relevant genes and activities of relevant enzymes. …”
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1878
“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station
Published 2025-04-01“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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1879
The Assessment of Utility and the Role of Rural Entrepreneurship Ecosystem in West Azerbaijan Province
Published 2017-08-01“…The statistical community of current research includes local experts (such as members of Islamic councils of villages and villagers), which consists of 3108 people. 341 people were selected as the sample by stratified sampling using Cochran method. …”
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1880
Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review
Published 2025-02-01“…To synthesise the data, the richest sources were identified through rereading the studies. …”
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