Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer’s Disease Diagnosis by Maria João Oliveira, Pedro Ribeiro, Pedro Miguel Rodrigues

“…<i>MCI</i>, the proposed model outperformed state-of-the-art imaging source studies by 0.1% and non-imaging source studies by 4.6%. …”
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Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3 by Lisa Morand-Laffargue, Florence Charles, Charlotte Sabran, Patrick Borel

“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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Preliminary Study on Natural Infection of Shellfish with Movement Disorder Nodavirus (MDNV) by Ping LI, Jitao XIA, Changming BAI, Ruidong XU, Tingting XU, Shuang LIU, Liang YAO, Xingtong YU, Qingli ZHANG

“…Shellfish is an important source of high-quality protein for human beings and simultaneously plays an important ecological service function in the marine ecosystem. …”
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CFD investigation and ANN prediction of heat transfer coefficient for fully developed turbulent air flow around double V-baffle turbulators by Abdulaziz Alasiri, H.E. Fawaz

“…The process of training incorporates the analysis of the loss function on training and validation data for controlling the weights and biases using backpropagation while feed forward propagate the selected input parameters. …”
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A competing risk analysis of predictors of time to lost to follow-up among adults with TB/HIV coinfection in Bahir Dar by Robel Demelash, Getachew Hailu, Taye Abuhay, Zemenu Addis, Ayenew Tega, Degarege Nibret, Yitagesu Habtu

“…Overestimating effect sizes when considering mutually exclusive events, like LTFU from ART and anti-TB treatment, can occur if sources of error are not properly accounted for in competing events. …”
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A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention by You Zhai, Hongcai Shang, Yan Li, Nan Zhang, Jisi Zhang, Shangwen Wu

“…ObjectiveThis study aims to systematically review the risk factors for major adverse cardiovascular events (MACE) in patients with coronary heart disease who have undergone percutaneous coronary intervention (PCI).DesignSystematic review and meta-analysis.Data sourcesThe Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals (VIP) were screened until December 2024.Eligibility criteria for selecting studiesCase-control studies or cohort studies on the risk factors for MACE in patients with coronary heart disease who underwent PCI. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c &gt;7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda. by Jonathan Kitonsa, Onesmus Kamacooko, Ubaldo Mushabe Bahemuka, Freddie Kibengo, Ayoub Kakande, Anne Wajja, Vincent Basajja, Alfred Lumala, Edward Ssemwanga, Robert Asaba, Joseph Mugisha, Benjamin F Pierce, Robin Shattock, Pontiano Kaleebu, Eugene Ruzagira

“…Data were analysed descriptively and a binomial generalised linear model with a log link function used to investigate factors associated with unwillingness to participate.…”
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Persistence in the socio-economic development of the regions of the Siberian Federal District by Misak S. Arzumanyan

“…The term «persistence» originally has a biological and medical origin, as a property of microorganisms (bacteria, viruses) to survive and function in an aggressive environment (e.g., when exposed to antibiotics). …”
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The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs by Omar T. F. Ahmed, Ziyad Tarek Ahmed, Abdulrahman W. Dairi, Maha Saad Zain Al-Abeden, Mohammed H. Alkahlot, Rana H. Alkahlot, Ghazi I. Al Jowf, Lars M. T. Eijssen, Khawaja Husnain Haider

“…The data were then plotted for various outcomes, including death, hospitalization, major adverse cardiac events, pump function parameters, and 6-min walk distance. Results The safety of MSC-based treatment has been consistently demonstrated with MSCs from autologous (AutoMSCs) and allogeneic (AlloMSCs) sources. …”
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Worlds Next Door: A Candidate Giant Planet Imaged in the Habitable Zone of α Centauri A. II. Binary Star Modeling, Planet and Exozodi Search, and Sensitivity Analysis by Aniket Sanghi, Charles Beichman, Dimitri Mawet, William O. Balmer, Nicolas Godoy, Laurent Pueyo, Anthony Boccaletti, Max Sommer, Alexis Bidot, Elodie Choquet, Pierre Kervella, Pierre-Olivier Lagage, Jarron Leisenring, Jorge Llop-Sayson, Michael Ressler, Kevin Wagner, Mark Wyatt

“…Additionally, postprocessing with the principal-component-analysis-based Karhunen–Loéve image processing algorithm reveals a point source, called S 1, in 2024 August, detected at signal-to-noise ratio of 4–6 (3.3–4.3 σ ), a projected separation of ≈1 $\mathop{.}…”
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Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics by Haiting Huang, Yu Liu, Jianmu Su, Xiangxiu Liang, Hong Wu, Mei Bai

“…Flavonoids related to medicinal effects, such as naringin and hesperidin, were significantly more abundant in Huazhou pomelo than in Sanhong pomelo, with compounds such as 5-demethylnobiletin detected only in Huazhou pomelo. The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Rock Fracture Monitoring Based on High-Precision Microseismic Event Location Using 3D Multiscale Waveform Inversion by Yi Wang, Xueyi Shang, Kang Peng, Rui Gao

“…Results show that the source-time function based on the fractional-order Gaussian function wavelet can better fit complex recording waveforms compared with the conventional Ricker wavelet-based source-time function, and the waveform misfit during the L-BFGS iteration decreased rapidly. …”
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Nanoprobe synchrotron X-ray fluorescence microscopy reveals selenium-rich spherical structure in mouse retinal pigment epithelium by Marta Ugarte, Kalotina Geraki, Elizabeth Bentley, Roger Cox

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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…While OSM is a valuable source of information, it is not exempt from inconsistencies and errors, particularly affecting pedestrian and cycling networks, which can lead to inaccurate navigation or unsafe routes. …”
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Construction of a Multi-level Blue-Green Infrastructure Network in a Riverside City: A Case Study of Shaoxing by Meizi Zhou, Yong He, Zhi Qiu

“…To address this gap, this study proposes a framework for constructing a multi-level BGI network. We selected Shaoxing City, a typical riverside city in the Yangtze River Delta region of China, as the study area and integrated water-related ecosystem services into the identification of ecological sources. …”
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Assessing motor control and movement quality in patients with non-specific low back pain: a scoping review and development of an ICF-based conceptual framework by Kerstin Luedtke, Agnes Sturma, Georg Pfluegler, Meike Klinger, Clemens Ley, Beate Schüßler

“…A thematic approach was used in an iterative process to identify broader themes in the data synthesis.Data sources MEDLINE, CINAHL, EMBASE, Web of Science, Scopus, Cochrane Library, COSMIN database and DiTA were systematically searched as part of a three-step search strategy (last search: 22 April 2025).Eligibility criteria for selecting studies Various types of evidence (qualitative and quantitative, primary and secondary) exploring and discussing movement tasks for assessing lumbopelvic motor control and movement quality in adult patients with non-specific LBP were considered. …”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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MULTI-MODEL STACK ENSEMBLE DEEP LEARNING APPROACH FOR MULTI-DISEASE PREDICTION IN HEALTHCARE APPLICATION by Bhaskar Adepu, T. Archana

“…These datasets serve two functions: improving illness prediction and examining large data reservoirs to identify previously unknown disease patterns. …”
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