Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry by Yash Mehta, Dhavalkumar Patel, Iqra Pervaiz, Ulrich Bickel, Abraham Jacob Al-Ahmad

“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat by Fahad Ali Kazmi, Ülo Mander, Ramita Khanongnuch, Maarja Öpik, Reti Ranniku, Kaido Soosaar, Mohit Masta, Salla A. M. Tenhovirta, Kuno Kasak, Claudine Ah-Peng, Mikk Espenberg

“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
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Leveraging artificial intelligence for photo identification to aid CITES enforcement in combating illegal trade of the endangered humphead wrasse (Cheilinus undulatus) by C. Y. Hau, W. K. Ngan, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson

“…A Licence to Possess system for CITES is implemented in the city to regulate the quota of live wild-sourced CITES specimens, including humphead wrasse, held at each registered trading premise and ensure traceability through documentation. …”
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Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§ by Nita Kaushik, Aradhita Barmanray

“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
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Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China by Jin Zheng, Yusheng Lu, Peizhi Xu, Kaizhi Xie, Changmin Zhou, Yaying Li, Haoyang Geng, Qianyuan Wang, Wenjie Gu

“…Paddy fields are the main agricultural source of greenhouse gas methane (CH₄) emissions. …”
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In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu... by Evangelia N. Kerezoudi, Marigoula Vlassopoulou, Evdokia K. Mitsou, Georgia Saxami, Georgios Koutrotsios, Ioanna Taflampa, Konstantinos C. Mountzouris, Ignacio Rangel, Robert J. Brummer, Georgios I. Zervakis, Vasiliki Pletsa, Panagiotis Georgiadis, Adamantini Kyriacou

“…Overall, the findings highlight the beneficial effect of PE on intestinal health of older adults supporting its potential incorporation into innovative functional foods. However, additional in vivo studies are required to substantiate these findings before translating them into dietary guidelines or clinical applications.…”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…However to date, the effect of HSCT on functional and morphological pulmonary changes in recipients remains insufficiently studied.The objective of current study was to evaluate risk factors affecting long-term survival in children and adolescents after allo-HSCT.Methods and materials. …”
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The amino acid composition of Polygonum hydropiper L. and Polygonum persicaria L. herbs of Ukrainian flora by I. A. Lukina, O. V. Mazulin, H. P. Smoilovska, H. V. Mazulin, I. N. Shevchenko

“…Plant amino acids play an important role in the functioning of various systems and organs of the human body and are characterized by distinct pharmacological properties, as well as contribute to more rapid absorption and potentiate the effect of other biologically active compounds present in plants. …”
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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…Neurotransmitter maps were sourced from JuSpace. We performed volumetric and whole-brain correlation analyses to evaluate relationships between brain regional volumes (BRVs) and neurotransmitter pathways. …”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…Fatty acids, among other substrates, are utilized by immune cells as an energy source. Therefore, L-carnitine, which is authorized as a feed additive in cattle, may influence the metabolism of peripheral blood mononuclear cells (PBMC) during an immune challenge. …”
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iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health by Yao Wang, Huiyu Hou, Hao Luo, Jiani Xun, Chuang Ma, Haifei Yang, Defeng Bai, Salsabeel Yousuf, Hujie Lyu, Tianyuan Zhang, Xiulin Wan, Xiaofang Yao, Tengfei Ma, Yuanping Zhou, Zhihao Zhu, Meiyin Zeng, Sanqi An, Qing Bai, Yao Bai, Guodong Cao, Tingting Cao, Yongkai Cao, Chihmin Chang, Lijia Chang, Bo Chen, Dai Chen, Dijun Chen, Hanqing Chen, Jiali Chen, Jinfeng Chen, Wei‐Hua Chen, Xinhai Chen, Yue Chen, Zhangran Chen, Cheng Cheng, Quan Cheng, Xi‐Jian Dai, Chaowen Deng, Feilong Deng, Jingwen Deng, Chang‐Sheng Dong, Lei Dong, Lianhui Duan, Yi Duan, Qingjie Fan, Chao Fang, Tingyu Fang, Wensheng Fang, Zhencheng Fang, Min Fu, Minjie Fu, Cong Gao, Hao Gao, Weiwei Gao, Xinrui Gao, Yi‐Zhou Gao, Yan Geng, Wenping Gong, Shaohua Gu, Xia Gu, Zhengquan Gu, Jian‐Wei Guo, Junjie Guo, Qiuyan Guo, Xiang Guo, Xiaoqian Guo, Dongfei Han, Ziyi Han, Yanan Hao, Jiale He, Jianquan He, Jianyu He, Ruolin He, Guosen Hou, Bin Hu, Haibo Hu, Yi Hu, Yongfei Hu, Yucan Hu, Guanyin Huang, Haiyun Huang, Jiaomei Huang, Shenghui Huang, Baolei Jia, Xingxing Jian, Chao Jiang, Kun Jiang, Lanyan Jiang, Shuaiming Jiang, Jian‐Yu Jiao, Hao Jin, Jiajia Jin, Siyuan Kong, Xinxing Lai, Yuxin Leng, Bang Li, Bing Li, Fang Li, Hao Li, Huanjie Li, Jing Li, Kai Li, Lanqi Li, Leyuan Li, Minghan Li, Pengsong Li, Wei Li, Wei Li, Xianyu Li, Li Xuemeng, Yafei Li, Yuantao Li, Zhi Li, Liqin Liang, Rong Liang, Zhuobin Liang, Qingya Liu, Dejian Liu, Huiheng Liu, Jinchao Liu, Li Liu, Lihui Liu, Moyang Liu, Ran Liu, Shuai Liu, Tianyang Liu, Wei Liu, Wenjuan Liu, Xiaomin Liu, Yang Liu, Yichen Liu, Yina Liu, Yuan Liu, Zhe Liu, Zhipeng Liu, Zhiquan Liu, Chunhao Long, Yun Long, Changying Lu, Chao Lu, Cheng Lu, Qi Lu, Yaning Luan, Peng Luo, Sheng Luo, Ning Ma, Xiao‐Ya Ma, Yan Ma, Wenjun Mao, Yuanfa Meng, Yan Ni, Yawen Ni, Kang Ning, Dongze Niu, Kai Peng, Zhengwu Peng, Xubo Qian, Zhiguang Qiu, Hui Qu, Zepeng Qu, Yan Ren, Zhigang Ren, Youming Shen, Lin Shi, Linlin Shi, Wenxuan Shi, Yongpeng Shi, Tianyuan Song, Xiaohui Song, Xiaoming Song, Xiaowei Song, Qi Su, Yufan Su, Lifang Sun, Qiang Sun, Tiefeng Sun, Yunke Sun, Hua Tang, Wenjing Tang, Tao Yu, Simon Tian, Shuo Wang, Bowen Wang, Cheng Wang, Wang Jin, Leli Wang, Liangliang Wang, Lixiao Wang, Mingbang Wang, Ming‐Ke Wang, Pingyi Wang, Shaolin Wang, Shaopu Wang, Xinxia Wang, Xueqiang Wang, Mi Wei, Yan Wei, Yanxia Wei, Yongjun Wei, Chaoliang Wen, Xin Wen, Linkun Wu, Shengru Wu, Yuting Wu, Shuting Xia, Xiaodong Xia, Yu Xia, Xionggen Xiang, Chuanxing Xiao, Weihua Xiao, Yingping Xiao, Ruohan Xie, Rui Xing, Hui Xu, Wei Xu, Zhimin Xu, Hongliang Xue, Chao Yan, Qiu‐Long Yan, Shaofei Yan, Xiuchuan Yan, Mengli Yang, Yufan Yang, Zhipeng Yang, Ziyuan Yang, Guixiang Yao, Yanlai Yao, Xianfu Yi, Chong Yin, Mingliang Yin, Shicheng Yu, Ying Yu, Yongyao Yu, Fusong Yuan, Shao‐Lun Zhai, Bo Zhang, Chen Zhang, Fang Zhang, Feng‐Li Zhang, Hengguo Zhang, Jinping Zhang, Junya Zhang, Kun Zhang, Li Zhang, Lin Zhang, Lingxuan Zhang, Meng Zhang, Qian Zhang, Runan Zhang, Tongtong Zhang, Tongxue Zhang, Weipeng Zhang, Yong Zhang, Yuchao Zhang, Yujun Zhang, Zeng Zhang, Zhengxiao Zhang, Zhi‐Feng Zhang, Boxi Zhao, Yanyan Zhao, Yibing Zhao, Ziwei Zhao, Diwei Zheng, Ying Zheng, Wenqiang Zhi, Jixin Zhong, Xiangjian Zhong, Wei Zhou, Xin Zhou, Zhemin Zhou, Zhichao Zhou, Congmin Zhu, Feiying Zhu, Xiaodie Zhu, Yutian Zou, Hongling Zhou, Lei Lei, Yanliang Bi, Hubing Shi, Hui‐Zeng Sun, Shuangxia Jin, Wenkai Ren, Lei Dai, Xin Wang, Canhui Lan, Hongwei Liu, Shuang‐Jiang Liu, Yulong Yin, Chun‐Lin Shi, Ren‐You Gan, Fangqing Zhao, Jun Yu, Tong Chen, Xin Hong, Hua Yang, Bangzhou Zhang, Shifu Chen, Xiaodong Li, Yunyun Gao, Yong‐Xin Liu

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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins by Ruolan Yi, Jiaoyang Zheng, Zhichao Xu, Jiayan Wu, Fangfang Liu, Jinxin Zheng, Duoyun Li, Shiqing Han, Zhijian Yu

“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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Proteomic analysis of plasma unravels dynamic pathways and potential biomarkers indicating disease stages following Mtb infection by Zonglei Zhou, Jie Tian, Yuying He, Haiyan Xiong, Weibing Wang

“…ABSTRACT Tuberculosis (TB) stages depend greatly on the interaction between Mycobacterium tuberculosis (Mtb) and the host response. As a non-negligible source of active tuberculosis (ATB), individuals with latent Mtb infection (LTBI) are insidious and hard to be detected due to limited biomarkers. …”
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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer by Qing Wang, Maha Ayyoub, Olivia Le Saux, Paola Bonaventura, Isabelle Treilleux, Nicolas Chopin, Clarisse Dubois, Virginie Mutez, Nicolas Chuvin, Yann Estornes, Jenny Valladeau-Guilemond, Stephane Depil, Nicolas Gadot, Marie Michelas, Audrey Page, Olivier Tabone, Marie Delles, Sarah Moran, Thibault Richard, Marjorie Lacourrège, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez

“…Furthermore, in vitro stimulation of patient T cells induced functional epitope-specific T cells, confirming the immunogenicity of these epitopes in patients with ovarian cancer. …”
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Metallurgical Waste for Sustainable Agriculture: Converter Slag and Blast-Furnace Sludge Increase Oat Yield in Acidic Soils by Olga V. Zakharova, Peter A. Baranchikov, Svetlana P. Chebotaryova, Gregory V. Grigoriev, Nataliya S. Strekalova, Tatiana A. Grodetskaya, Igor N. Burmistrov, Sergey V. Volokhov, Denis V. Kuznetsov, Alexander A. Gusev

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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…In the present study, we show that replacing ECB balance sheet size with random numbers leads to statistically indistinguishable shock response functions and time series of abnormal monetary policy shocks. …”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…The key findings in this segment were: Organizational The practice of reuse currently functions as an appendix of the demolition industry, bringing benefits as well as disadvantages. …”
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes by Praveen Patel, Rory Collins, Richard Peto, Mark Davies, Sanjiv Banerjee, David Simpson, John Anderson, Louise Bowman, Peter Scanlon, Amanda Adler, Andrew Farmer, Helen Cook, Laura Evans, Elizabeth Williamson, Louis Bolter, Jane Armitage, Peter Sandercock, Richard Gray, Nilesh Samani, Tasso Gazis, Richard Haynes, Arun Sachdev, Eric Wu, Elizabeth Wincott, Peter Sleight, Colin Baigent, Marion Mafham, Sarah Parish, Gavin Brown, Susan Hurley, Lynne Allsop, William Stevens, Theingi Aung, Allen Young, Emily Sammons, Georgina Buck, Imen Hammami, Jill Barton, Jonathan Bodansky, Roger McPherson, Lucy Fletcher, Murphy Kevin, Ryonfa Lee, Sandra Pickworth, Monica Willett, Michael Lay, Ola Murawska, Karen Melham, Jonathan Latham-Mollart, Anna Brewer, Mike Olson, Jude Kay, Alisha Griffiths, Helen Clayton, Philip Kirby, Mike Pennington, Dominic Clarke, Jenny Anslow, Alex Hallam, Jenny Witts, Sarah Egan, Alex Wharton, Amy Derbyshire, Katherine Hepplestone, Sujit Mithra, Su Oliver, Pauline Wiatrak-Olszewska, Kelly Alvey, Nick Gregory, Priyai Parkinson, Prema Maharajan, Rachel McFee, Donna Sowter, John Featonby, Richard Furnival, Helen Lipinski, Hazel Benjamin, Tanisha McAfee, Emma Payne Payne, Liz Still

“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Multiple imputation by chain equations was used to handle missing data and fractional polynomial functions were used to fit continuous variables. The discriminative ability of the models was assessed using the c-index, and calibration was assessed using calibration plots and the calibration slope. …”
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