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601
Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease.
Published 2024-01-01“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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602
TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury
Published 2025-05-01“…The ratio, number, phenotype, and function of immune cells and cytokine levels were measured. …”
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603
Glucose Sensing in Saliva
Published 2024-11-01“…Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. …”
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604
Synthesis and Production of Sweet-Tasting Protein in E. coli and Purification by Amylose Resin
Published 2011-06-01“…However, the extraction of brazzein from its natural source is expensive and not applicable. In this study we used recombinant DNA technology to provide an alternative option for cheaper mass production of brazzein. …”
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605
Multiwavelength Constraints on the Local Black Hole Occupation Fraction
Published 2024-01-01“…We also constrain the extremely low-luminosity end ( L _bol ≲ 10 ^40 erg s ^−1 ) of the active galactic nucleus (AGN) luminosity functions at z = 0. Our AGN luminosity functions are broadly consistent with an extrapolation of the shallow slope of the AGN luminosity functions from previous work.…”
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606
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607
Transcriptome analysis of corpora lutea in domestic cats (Felis catus) reveals strong differences in gene expression of various hormones, hormone receptors and regulators across di...
Published 2025-03-01“…Abstract In the domestic cat (Felis catus), the corpus luteum (CL) is the main source of progestogen during pregnancy. Here, we studied gene expression changes in different life cycle stages of the CL of pseudopregnant cats to identify potential regulatory factors. …”
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608
Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis
Published 2024-12-01“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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609
A Benzimidazole-Based Fluorescent Probe for the Selective Recognition of Cobalt (II) Ions
Published 2025-08-01“…However, excessive cobalt intake can cause health issues. Detecting cobalt ions, especially Co<sup>2+</sup>, in food is crucial due to potential contamination from various sources. …”
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610
PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm
Published 2021-01-01“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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611
Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons
Published 2025-03-01“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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612
Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible
Published 2025-05-01“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
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613
Quantifying Streambed Grain Size, Uncertainty, and Hydrobiogeochemical Parameters Using Machine Learning Model YOLO
Published 2024-11-01“…Abstract Streambed grain sizes control river hydro‐biogeochemical (HBGC) processes and functions. However, measuring their quantities, distributions, and uncertainties is challenging due to the diversity and heterogeneity of natural streams. …”
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614
Genome-Wide Scan for Copy Number Variations in Chinese Merino Sheep Based on Ovine High-Density 600K SNP Arrays
Published 2024-10-01“…Copy number variations (CNVs) have emerged as one of the most important sources of genetic variation, influencing phenotypic traits by altering gene expression and dosage. …”
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615
The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride.
Published 2014-01-01“…Here we analyzed the functions of the T. atroviride Ste12 transcription factor whose orthologue in yeast is targeted by the Fus3 and Kss1 MAP kinases. …”
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616
Pearls on a String: Dark and Bright Galaxies on a Strikingly Straight and Narrow Filament
Published 2025-01-01“…We study the cold H i gas in a 1.3 Mpc section of the filament through H i 21 cm emission line observations and detect 11 H i sources, many more than expected from the H i mass function in a similar volume. …”
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617
Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS
Published 2025-04-01“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
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618
Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs
Published 2025-08-01“…An interaction effect between the dietary protein source and protein level could be detected for the phagocytic activity of blood granulocytes as well as for the plasma concentrations of IgA and IgE. …”
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619
Mitigating malicious denial of wallet attack using attribute reduction with deep learning approach for serverless computing on next generation applications
Published 2025-05-01“…Abstract Denial of Wallet (DoW) attacks are one kind of cyberattack whose goal is to develop and expand the financial sources of a group by causing extreme costs in their serverless computing or cloud environments. …”
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620
Subclinical Aortic Root Pathology in Close Relatives of Patients with Bicuspid Aortic Valve
Published 2013-12-01“…According to various sources, among the relatives of the first degree (FDR) of affinity the prevalence of BAV is 9.0-21.0%. …”
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