Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy by Ping Li, Alice Butler, Yu Zhou, Karl L. Magleby, Christina A. Gurnett, Lawrence Salkoff

“…The Kv3.2 subfamily of voltage activated potassium channels encoded by the KCNC2 gene is abundantly expressed in neurons that fire trains of fast action potentials that are a major source of cortical inhibition. Gain-of-function (GOF) de novo pathogenic variants in KCNC1 and KCNC2, encoding Kv3.1 and Kv3.2 respectively, cause several types of epilepsy including developmental and epileptic encephalopathy (DEE). …”
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Identification of Cancer Stem Cell (CSC)-Associated Genes, Prognostic Value, and Candidate Drugs as Modulators of CSC-Associated Signaling in Carcinomas Through a Multiomics Data A... by Pallabi Mondal, Poulami Singh, Krishna Mahanti, Sankar Bhattacharyya

“…This ability of CSCs to escape immune responses makes the CSCs a primary source of functionally altered, immune-resistant, chemoresistant, aggressive tumor cells. …”
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Reduction of Total Phenols in Virgin Olive Oil as a Preservation Medium during Cold Storage of Whey Cheese and Tofu by Valerija Majetić Germek, Ivana Gobin, Doris Franjković, Marija Marković, Olivera Koprivnjak

“…Virgin olive oil, known as a good source of health-promoting hydrophilic phenols, is traditionally used as a medium for preserving various foods. …”
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Bifidobacterium animalis subsp. lactis genome resources and metabolite profiling at the strain level and their ability to alleviate anxiety-like behavior in a sleep-deprived mouse... by Yao-Kun Zhang, Liang Zhang, Xue Ni, Shu-Wen Zhang, Min-Zhi Jiang, Si-Lu Zhang, Guo-Xun Xiao, He Jiang, Ming-Xia Bi, Yu-Lin Wang, Chang Liu, Shuang-Jiang Liu

“…In this study, we characterized 16 B animalis subsp. lactis isolates from fecal samples and probiotic sources. We assessed the genotype-phenotype correlations related to growth, carbon source utilization, and stress tolerance in vitro. …”
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A metabolic profiling approach to characterize and discriminate plant-based beverages and milk by Gaia Meoni, Ingrid Sousa, Leonardo Tenori, Giovanni Niero, Marta Pozza, Massimo De Marchi, Carmen L. Manuelian

“…ABSTRACT: The rising demand for nondairy and nonanimal protein sources has increased plant-based beverages (PBB) consumption. …”
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Provenance-Finding of Dust Storms Using AVHRR Sensor Images of NOAA Satellite (Case Study: Southwest of Iran) by Mohammad Hossein Rezaei Moghaddam, Mojtaba Mahdian Boruojeni

“…Dust pollution of this area drawn to the south of Khuzestan. 4- Conclusion In general, using 24 AVHRR images and the use of detection techniques, a total 62 points were identified as the source of dust production. …”
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Weibull-Type Incubation Period and Time of Exposure Using <i>γ</i>-Divergence by Daisuke Yoneoka, Takayuki Kawashima, Yuta Tanoue, Shuhei Nomura, Akifumi Eguchi

“…Accurately determining the exposure time to an infectious pathogen, together with the corresponding incubation period, is vital for identifying infection sources and implementing targeted public health interventions. …”
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The burden of intracerebral hemorrhage attributable to ambient particulate matter pollution in five Asian countries: a 32-year comparative analysis by Rui Yang, Xingke Wang, Panpan Hao

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Investigation of TsGAN-based multimodal image fusion to augment image pre-processing abilities by Priyanka Bhatambarekar, Gayatri Phade

“…The TSGAN framework generates a unified texture map that captures essential gradient preservation into the generator’s loss function, the model successfully retains critical information about texture from the input source images. …”
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Modelling and Forecasting Energy Efficiency Impact on the Human Health by Yuliia Matvieieva, Hedy Ben Hamida

“…In the study framework, the VOSviewer 1.6.18 tools allowed the detection of six clusters of research streams: renewable resources, sustainable development, public, energy policy, energy efficiency, and solar energy. …”
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Preliminary Design of a GNSS Interference Mapping CubeSat Mission: JamSail by Luis Cormier, Tasneem Yousif, Samuel Thompson, Angel Arcia Gil, Nishanth Pushparaj, Paul Blunt, Chantal Cappelletti

“…First, a flexible, low-cost GNSS interference detection payload capable of characterising and geolocating the sources of radio interference regarding the E1/L1 and E5a/L5 bands will be demonstrated on a global scale. …”
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Double-moment normalization of hail size number distributions over Switzerland by A. Ferrone, J. Kopp, M. Lainer, M. Gabella, U. Germann, A. Berne

“…These results highlight the invariance of the normalized distribution and the adaptability of the method to different data sources.</p>…”
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THEORY AND PRACTICE OF ASSESSING THE LEVEL OF INSTABILITY OF THE EXTERNAL ENVIRONMENT OF THE ENTERPRISE IN A HYBRID WAR by I. Zapukhliak, A. Shegda, О. Mykytiuk, T. Onysenko, K. Petrenko

“…The article proposes a methodological approach to comprehensive assessment of the level of instability of environmental factors of enterprises, which, unlike others, involves the detection of instability in terms of seven components (socio-demographic, economic, technological, environmental, political, legal, ethical) on four criteria: complexity, interdependence, variability and uncertainty of factors, which makes it possible to determine their sources and nature, and thus form an effective response of the enterprise to change. …”
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Machine learning models for clinical and structural knee osteoarthritis prediction: Recent advancements and future directions by Gabby B. Joseph, Charles E. McCulloch, Michael C. Nevitt, Nancy E. Lane, Sharmila Majumdar, Thomas M. Link

“…These evolving strategies underscore the growing potential of ML to improve the detection of early OA, individualized risk stratification, and personalized interventions in OA clinical care.…”
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SCIENTIFIC AND PRACTICAL APPROACHES TO THE FORMATION OF READINESS OF FUTURE SPECIALISTS IN THE SOCIONOMIC SPHERE FOR THE SOCIAL SUPPORT FOR PARENTS OF CHILDREN WITH SPECIAL NEEDS by Sapozhnykov Stanislav, Teplytska Alina

“…The article states that the integration of the above-presented scientific and practical approaches to the formation of a certain level of readiness in future specialists in the higher education system of Ukraine is realized in practical activities via the selection of the appropriate content of tasks, methods, techniques, forms and teaching tools. …”
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Pollution Characteristics and Water Quality Status of Water Storage Pond in Xianyang City of Shaanxi Province by Zhou Fuyu, Gao Zhaoliang, Zhang Shuai, Li Yonghong, Sun Guanfang, Lou Yongcai, Ai Jianwei, Liu Wenbo

“…Treatment methods suitable for the rural environment should be selected according to the characteristics of water pollution.…”
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Recent Advances and Challenges in the Production of Hydroxylated Natural Products Using Microorganisms by Chang Sun, Rumei Zeng, Tianpeng Chen, Yibing Yang, Yi Song, Qiang Li, Jie Cheng, Bingliang Liu

“…Hydroxylation reaction is a significant source of structural diversity in natural products (NPs), playing a crucial role in improving the bioactivity, solubility, and stability of natural product molecules. …”
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Humic acids as drivers of plant growth: regulating root development and photobiology through redox modulation by Daniel Basílio Zandonadi, Hiarhi Monda, Jason Gralian, Aletia James, Richard T. Lamar, Mirella Pupo Santos

“…Abstract Background Humic acids (HA) influence plant growth and development through various mechanisms that depend on the source and concentration of HA, as well as the specific plant organ and its developmental stage. …”
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Pollution Risk Assessment of Potentially Toxic Elements in Soils Using Characterization and Microbiological Analysis: The Case of a Rare and Precious Metal Mining Site in Wuzhou, G... by Yi Sun, Zixuan Yang, Kun Dong, Fujiang Hui, Dunqiu Wang, Yecheng Huang

“…The Probability Mass Function (PMF) model was used to perform a source apportionment of the PTEs and determine the main pollution sources and their contribution rates. …”
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Unlocking health insights: exploring intention to adopt district health information systems in Bahir Dar City, northwest Ethiopia by Habtamu Alganeh Guadie, Amarech Kindie, Hunegnaw Almaw Derseh, Desta Debalkie Atnafu

“…BackgroundDistrict Health Information System version 2 (DHIS2) is an open-source platform designed for data collection, processing, analysis, and visualization within healthcare systems. …”
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