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A competing risk analysis of predictors of time to lost to follow-up among adults with TB/HIV coinfection in Bahir Dar
Published 2025-08-01“…Overestimating effect sizes when considering mutually exclusive events, like LTFU from ART and anti-TB treatment, can occur if sources of error are not properly accounted for in competing events. …”
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A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention
Published 2025-04-01“…ObjectiveThis study aims to systematically review the risk factors for major adverse cardiovascular events (MACE) in patients with coronary heart disease who have undergone percutaneous coronary intervention (PCI).DesignSystematic review and meta-analysis.Data sourcesThe Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals (VIP) were screened until December 2024.Eligibility criteria for selecting studiesCase-control studies or cohort studies on the risk factors for MACE in patients with coronary heart disease who underwent PCI. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o...
Published 2013-03-01“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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1764
Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda.
Published 2021-01-01“…Data were analysed descriptively and a binomial generalised linear model with a log link function used to investigate factors associated with unwillingness to participate.…”
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Persistence in the socio-economic development of the regions of the Siberian Federal District
Published 2024-01-01“…The term «persistence» originally has a biological and medical origin, as a property of microorganisms (bacteria, viruses) to survive and function in an aggressive environment (e.g., when exposed to antibiotics). …”
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Isolation and Characterization of L-Asparaginase-Producing Bacteria from the Arabian–Persian Gulf Region: First Report on <i>Bacillus xiamenensis</i> ASP-J1-4 as a Producer and Its...
Published 2025-04-01“…L-asparaginase (L-ASNase) functions as a chemotherapeutic enzyme with antitumor properties. …”
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Life cycle assessment of an entirely wood floor system designed for carbon negativity, future adaptability, and end-of-life de/re/construction
Published 2025-01-01“…Mass timber offers a promising alternative, with lower embodied carbon (EC) and the potential to function as a carbon sink when sustainably sourced. …”
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1768
Multimessenger Signatures of a Deformed Magnetar in Gamma-Ray Bursts
Published 2025-01-01“…It is shown that the GW and EM emissions evolve as a function of eccentricity and rotational frequency with time. …”
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In situ, modeled, and earth observation monitoring of surface water availability in West African rangelands
Published 2025-06-01“…The 12 locations can function as sentinel ponds to monitor local water availability. …”
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Identification of miRnas with possible prognostic roles for HAM/TSP
Published 2023-12-01“…The seven most deregulated miRs target genes have been associated with a variety of biological processes and molecular functions. The reactome pathways relevant to our findings provide a rich source of data and offer the opportunity to better understand sRNA regulation and function in HTLV-1 pathophysiology. …”
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Epidemiology of Disability of Adult Population in the Russian Federation
Published 2019-11-01“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers
Published 2025-01-01“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1α Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
Published 2025-04-01“…<b>Background:</b> Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional coactivator p300, a critical step for promoting cancer cell survival and adaptation in hypoxic environments. …”
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Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System
Published 2025-06-01“…The implementation of cacao SAF is anticipated to enhance cacao productivity, improve the welfare of local communities, and preserve the forest’s function as a crucial life support system for the Dayak Community in Mahakam Ulu (Mahulu) District. …”
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Path to Heritagization in Landscape Architecture: A Review of the Regeneration Design of Beijing Changchunyuan Park
Published 2025-03-01“…Undoubtedly, Changchunyuan Park adjacent to Changchun Temple is inherently bearing the same responsibility for cultural transmission. 2) Style and form selection: The traditional Beijing garden style is taken as the tone of “named composition” to regain the contemporary significance of traditional classic space. …”
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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c...
Published 2025-02-01“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. The m6aCRLncs linked to EC were identified through co-expression analysis. …”
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There is no transfer of mitochondria from donor hematopoietic cells to recipient mesenchymal stromal cells after allogeneic hematopoietic stem cells transplantation in humans
Published 2025-07-01“…Mitochondria, which can be transferred between cells via nanotubes or extracellular vesicles, play a key role in the functions of mesenchymal stromal cells. In a murine model, donor hematopoietic stem and progenitor cells transfer functional mitochondria to bone marrow mesenchymal stromal cells of the recipient. …”
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Growth Toxic Effects of Metal Nanoparticles on Bacillus subtilis and Vibrio parahaemolyticus
Published 2025-04-01“…Based on the ecological roles and functions of these two bacteria in marine microbial communities, this study used B. subtilis and V. parahaemolyticus isolated from Bohai Bay as test organisms. …”
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Trends and advances in Leptospira, a bibliometric analysis
Published 2025-01-01“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows
Published 2025-07-01“…Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. …”
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