Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement by Sen Luo, Xi Zhou, Meijing Wu, Gongxin Wang, Li Wang, Xujun Feng, Hang Wu, Ren Luo, Minjuan Lu, Junxian Ju, Wenxing Wang, Lei Yuan, Xiaoqing Luo, Dezheng Peng, Li Yang, Qingfeng Zhang, Minzhi Chen, Songping Liang, Xiuming Dong, Guoliang Hao, Yunxiao Zhang, Zhonghua Liu

“…Spider venom‐derived peptide toxins are recognized as significant sources of Nav1.7 inhibitors. However, their development has been impeded by limited selectivity. …”
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Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification by Li Li, Yuezhou Wang, Yiqiu Wang, Xiaoyang Li, Qihong Deng, Fei Gao, Wenhua Lian, Yunzhan Li, Fu Gui, Yanling Wei, Su-Jie Zhu, Cai-Hong Yun, Lei Zhang, Zhiyu Hu, Qingyan Xu, Xiaobing Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Fei Xia, Xianming Deng

“…Homo- or heterodimeric compounds that affect dimeric protein function through interaction between monomeric moieties and protein subunits can serve as valuable sources of potent and selective drug candidates. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Adolescent adaptive functioning was predicted not only by early childhood autistic symptoms and IQ and ADHD symptoms. …”
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Comparison of Fuzzy-AHP and ANP Decision Making Methods to Assess the Ecological Capability of Ecotourism Application (Case study: Dehloran National Natural Monuments) by Mohsen Tavakoli

“…Then, to combine the layers, the model of overlapping index or linear weight composition was used. 3-Results and Discussion Using the GIS on the slope of the linear reduction subscription function, the trajectory linear membership function layer and the temperature layer, an incremental linear membership function was applied. …”
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Effects of exogenous sugars on root sugar metabolism and antioxidant system under sub-low root-zone temperature in Malus baccata Borkh. by LIU Hanyu, WANG Peng, ZHOU Wenjie, SU Hong, LÜ Deguo, LI Lijie

“…And, sugar not only serves as structural material and an energy source but also has signaling functions to regulate the expression of relevant genes and activities of relevant enzymes. …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station by Fang WANG, Zhuoqi LI, Haoyi XU, Jiaqi YAN

“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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The Assessment of Utility and the Role of Rural Entrepreneurship Ecosystem in West Azerbaijan Province by ali Gholami, Fatemeh Moohamadzadeh

“…The statistical community of current research includes local experts (such as members of Islamic councils of villages and villagers), which consists of 3108 people. 341 people were selected as the sample by stratified sampling using Cochran method. …”
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Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review by Dikshyanta Rana, Sophie Westrop, Nishant Jaiswal, Evi Germeni, Arlene McGarty, Louisa Ells, Phillippa Lally, Michael McEwan, Craig Melville, Leanne Harris, Olivia Wu

“…To synthesise the data, the richest sources were identified through rereading the studies. …”
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A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6 by Fengwu Sun, Feige Wang, Jinyi Yang, Jaclyn B. Champagne, Roberto Decarli, Xiaohui Fan, Eduardo Bañados, Zheng Cai, Luis Colina, Eiichi Egami, Joseph F. Hennawi, Xiangyu Jin, Hyunsung D. Jun, Yana Khusanova, Mingyu Li, Zihao Li, Xiaojing Lin, Weizhe Liu, Romain A. Meyer, Maria A. Pudoka, George H. Rieke, Yue Shen, Wei Leong Tee, Bram Venemans, Fabian Walter, Yunjing Wu, Huanian Zhang, Siwei Zou

“…We identify eight DSFGs in seven fields at z = 4–6 through the detection of H α or [O  iii ] λ 5008 lines, including fainter lines such as H β , [O  iii ] λ 4960, [N  ii ] λ 6585, and [S  ii ] λλ 6718,6733 for six sources. …”
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Identification of Suitable Villages for Agritourism Development (A Case Study of Semirom County) by Narges Vazin, Ali Sadeghi, Zahra Barati

“…The results will be practical for planners and regional officials in selecting a suitable village for investment and agritourism development.…”
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An Examination and Critique of Bottom-Up Causation in the Interpretation of Free Will, Focusing on the Non-Reductionist Approach by Tayybhe Gholami, Zahra khazaei

“…A purposive sampling method was utilized to select texts that encompass a range of perspectives, including those of Sam Harris and Daniel Dennett.Data collection involved a systematic literature review, focusing on published works from the last two decades to ensure relevance. …”
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Comparing the Effectiveness of Self-Compassion and Mindfulness Therapies on Affection Control of Poor Parenting Adolescents by Zahra EffatDoost Sani, Mohammad Reza Zarbakhsh Bahri, Alireza Homayuni

“…The sample included 60 adolescents, who were voluntarily taking part in the study. They were selected and categorized in three groups (two experimental and one control) through purposeful sampling method. …”
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The Impact of Audit Quality on Organizational Capital and Financing Capacity by Somaye Fathi, Mahdi Bahar Moghadam, Kazem Shamsadini

“…These results collectively advance our understanding of audit quality's dual function as both an organizational capital enhancer and financial constraint moderator. …”
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Sustainable forest management: success and challenges in Ethiopia by Rusha Begna Wakweya

“…In Ethiopia, SFM encompasses various practices, including reforestation, selective harvesting, and participatory management, all of which are informed by both ecological and socio-economic considerations. …”
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Social Confrontation with Menstruation: A Feminist Ethnography of Menstrual Experience among Female Instagram Users by Rana Mohammad Taghinejad Esfahani, Majid Movahed, Halimeh Enayat, Aliyar Ahmadi

“…This study examined women’s experiences of menstruation on Instagram and explored how menstruation taboos function as mechanisms for controlling women’s bodies within the existing power structures and daily life. …”
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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…We examined model fit by the posterior mean of the residual deviance and the deviance information criterion to select models. Pairwise MA and NMA were also carried out with a frequentist framework using the R functions ‘netmetabin’ and ‘netmeta’. …”
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Are Supernovae Responsible for the Gamma Ray Spectrum from the Galactic Center? by Todor Stanev

“…We discuss the supernova remnants distribution as a function of the galactic longitude and compare their positions to that of the detected TeV gamma ray sources. …”
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The 4–400 GHz Survey for the 32 Class II Disks in the Taurus Molecular Cloud by Chia-Ying Chung, An-Li Tsai, Melvyn Wright, Wenrui Xu, Feng Long, Mark A. Gurwell, Hauyu Baobab Liu

“…We have compiled the ∼4–400 GHz broad spectra of 32 Class II protoplanetary disks (PPDs) in the Taurus-Auriga region, which represents the brightest one-third of sources detected in the submillimeter band in this region. …”
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Visible Triple-Wavelength Switchable Emission Generated in Passively Q-Switched Nd:YVO₄ Self-Raman Laser by Songtao Li, Shengxi Zheng, Bowen Zheng, Yong Wei, Yongchang Zhang, Yanmin Duan, Haiyong Zhu

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