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741
Enzymatic system of glucose metabolism in Gluconobacter oxydans strain DHA3-9
Published 2014-03-01“…Pyruvate and acetate were detected in the products of mutant whereas none of such products were found in wild type culture. …”
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742
ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans.
Published 2022-06-01“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
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743
Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.
Published 2017-01-01“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
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744
Experimental Study of Coherent Collaborative Processing Method in Distributed Automotive Radar
Published 2025-03-01“…Intelligent driver assistance systems are increasingly employing radar systems to detect, resolve, and track various classes of targets. …”
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745
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.
Published 2014-01-01“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
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746
A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila.
Published 2022-05-01“…Wit, a second Type II receptor, shows a markedly different behavior, with the protein detected on all membrane regions but enriched at the apical side. …”
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747
Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum
Published 2021-01-01“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
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748
Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs
Published 2024-12-01“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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749
Near-infrared spectroscopy of the cerebellum in motor activation tasks
Published 2025-07-01“…Protocol 1 consisted of 5 optodes (4 sources and 1 detector, 4 recording channels) spaced 3 cm apart and comprising single-tipped LED light sources in conjunction with single-tipped fiber-optic detectors. …”
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750
New Rotation Periods from the Kepler Bonus Background Light Curves
Published 2025-01-01“…However, due to Kepler’s large 4″ pixels, many of its light curves are at high risk of contamination from background sources. The new Kepler Bonus Background light curves are deblended using a point-spread function algorithm, providing light curves of over 400,000 new background sources in addition to over 200,000 reanalyzed Kepler prime targets. …”
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751
Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema
Published 2024-01-01“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
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752
The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters
Published 2025-01-01“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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753
Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis
Published 2024-12-01“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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754
Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria
Published 2025-03-01“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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755
Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons
Published 2025-03-01“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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756
Preliminary Study on Natural Infection of Shellfish with Movement Disorder Nodavirus (MDNV)
Published 2025-08-01“…Shellfish is an important source of high-quality protein for human beings and simultaneously plays an important ecological service function in the marine ecosystem. …”
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757
Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability
Published 2024-10-01“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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758
Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media
Published 2025-01-01“…The analysis is done via the bvp4c MATLAB function in order to analyze the current model numerically by implementing convective boundary conditions. …”
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759
Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice
Published 2025-08-01“…Among T cells, particularly, Pdcd1+ γδ T cells were detected in necrotizing granulomatous lesions, suggesting their potential role in the pathogenicity of M. tuberculosis. …”
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760
Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05
Published 2024-12-01“…SEM analysis revealed morphological alterations, including cracks and holes, ATR-FTIR detected new functional groups (alcohols, alkynes, aldehydes, alkenes and ketones), while XRD identified changes in the polymer crystallinity and phase composition. …”
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