Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis by Zhengzheng Jiang, YaWen Shen

“…IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu... by Evangelia N. Kerezoudi, Marigoula Vlassopoulou, Evdokia K. Mitsou, Georgia Saxami, Georgios Koutrotsios, Ioanna Taflampa, Konstantinos C. Mountzouris, Ignacio Rangel, Robert J. Brummer, Georgios I. Zervakis, Vasiliki Pletsa, Panagiotis Georgiadis, Adamantini Kyriacou

“…The changes in bacterial communities upon fermentation at family, genera and species level were detected via 16S rRNA Next Generation Sequencing and Quantitative real-time PCR. …”
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Association of microtubule-based processes gene expression with immune microenvironment and its predictive value for drug response in oestrogen receptor-positive breast cancer by Zhenfeng Huang, Minghui Zhang, Nana Zhang, Mengyao Zeng, Yao Qian, Meng Zhu, Xiangyan Meng, Ming Shan, Guoqiang Zhang, Feng Liu

“…Transwell and cell viability assays were used to examine the biological functions of CHORDC1.ResultsTwo molecular subgroups with significantly different survival outcomes were identified. …”
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Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases by He Lu, Yaohui Jiang, Rui Luo, Dexing Zhou, Feihu Zheng, Liran Shi, He Zhang, Yong Wang, Xiaodong Xu, Renfang Zou, Yujing Zhou, Shuai Ren, Xiaocheng Wang, Haiqiang Sang

“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
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Overview of Effects of Motor Learning Strategies in Neurologic and Geriatric Populations: A Systematic Mapping Review by Li-Juan Jie, PhD, Melanie Kleynen, PhD, Guus Rothuizen, MSc, Elmar Kal, PhD, Andreas Rothgangel, PhD, Susy Braun, PhD

“…Data Sources: PubMed, CINAHL, and Embase were searched. …”
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Agroclimatic and agroecotoxicological justification of zonal chemical protection systems against harmful organisms for field crops under conditions of climate change in Ukraine by O. Borzykh, L. Bublyk, V. Chaika, L. Gavrylyuk, I. Kruk, O. Shevchuk, T. Neverovska, O. Bakhmut

“…This led to a disruption in the functioning of agrocenoses, a decrease in tolerance to the pesticide load. …”
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Bioactive matters based on natural product for cardiovascular diseases by Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou

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Non-Targeted Lipidomics Analysis of Characteristic Milk Using High-Resolution Mass Spectrometry (UHPLC-HRMS) by Tingting Wei, Tianxiao Zhou, Shenping Zhang, Zhexue Quan, Yang Liu

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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer by Qing Wang, Maha Ayyoub, Olivia Le Saux, Paola Bonaventura, Isabelle Treilleux, Nicolas Chopin, Clarisse Dubois, Virginie Mutez, Nicolas Chuvin, Yann Estornes, Jenny Valladeau-Guilemond, Stephane Depil, Nicolas Gadot, Marie Michelas, Audrey Page, Olivier Tabone, Marie Delles, Sarah Moran, Thibault Richard, Marjorie Lacourrège, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez

“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China by Jin Zheng, Yusheng Lu, Peizhi Xu, Kaizhi Xie, Changmin Zhou, Yaying Li, Haoyang Geng, Qianyuan Wang, Wenjie Gu

“…Paddy fields are the main agricultural source of greenhouse gas methane (CH₄) emissions. …”
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Big data for imaging assessment in glaucoma by Douglas R. da Costa, Felipe A. Medeiros

“…Leveraging vast data sources, these technologies promise to enhance clinical practice and public health outcomes by enabling earlier disease detection, progression forecasting, and deeper understanding of underlying mechanisms. …”
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Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
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Quality and content evaluation of thyroid eye disease treatment information on TikTok and Bilibili by Haisheng Wang, Huahong Zhang, Jiamin Cao, Feng Zhang, Wei Xiong

“…Abstract Thyroid eye disease (TED) is an autoimmune condition that commonly impacts patients’ visual function, appearance, and psychological well-being. …”
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Validation of the inadequate delivery of oxygen index in an adult cardiovascular intensive care unitCentral MessagePerspective by Heather Holman, BS, Dimitar Baronov, PhD, Jeff McMurray, MD, Arman Kilic, MD, Marc Katz, MD, Sanford Zeigler, MD

“…Conclusions: The IDO2 index is capable of detecting SvO2 ≤50% with good discriminatory function in non-MCS CVICU patients in a variety of monitoring situations. …”
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Advancements in Herpes Zoster Diagnosis, Treatment, and Management: Systematic Review of Artificial Intelligence Applications by Dasheng Wu, Na Liu, Rui Ma, Peilong Wu

“…Hospital-derived data were the primary source (15/26, 57.7%), followed by public databases (6/26, 23.1%) and internet data (5/26, 19.2%). …”
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Theoretical and technical concept of cemented backfill material for flexible enhanced thermal energy storage in coal underground space by Chao LYU, Wenyu LYU, Qiang SUN, Panshi XIE, Ding LANG, Songtao JI, Jianjun HU

“…In general, CBM–FETES realizes the full integration of mines and variable energy sources and enriches the connotation of filling mining. …”
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Vocational teacher training in Russia at the present stage: Conceptual aspect by В. A. Fedorov, P. F. Kubrushko, V. V. Dubitskiy, A. V. Feoktistov

“…The third component outlines the expected state indicated by the necessary conditions for the implementation of conceptual principles of vocational teacher training and concerning the selection of teaching content, building the structure of the system of vocational teacher training system supported with relevant management tools.Practical significance. …”
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Harmonic State Estimation Method Based on Bayesian Optimized Elastic Network Regression by Siqi MA, Zhong WANG

“…Firstly, when the least square method is used to estimate the harmonic state, the weighted 1-norm and 2-norm are added to the penalty function at the same time; In addition, in order to estimate the harmonic state more efficiently and accurately, the Gaussian process and Bayesian optimization are applied to select the weight of 1-norm and 2-norm; Finally, the effectiveness of the proposed method is verified in IEEE14 node. …”
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Efficacy and safety of musculoskeletal manipulations in elderly population with musculoskeletal disorders: a systematic review by Alessandro Mauro, Donatella Bagagiolo, Michela Persiani, Luca Cicchitti, Luca Vismara, Irene Bruini, Francesca Buffone

“…Introduction Non-pharmacological interventions, including musculoskeletal manipulations (MMs), have been proven effective for musculoskeletal disorders.Objectives To evaluate if MMs, including osteopathic manipulation and chiropractic care, are effective to improve quality of life, pain intensity and function in older adults with musculoskeletal disorders.Design Systematic review.Data sources A systematic search was conducted on MEDLINE/PubMed, EMBASE, Scopus, Web of Science, CINAHL, Cochrane Library, from database inception up to 2 January 2025.Eligibility criteria Randomised controlled trials, controlled non-randomised trials and open label trials evaluating the efficacy and safety of MM such as osteopathic manipulation, chiropractic manipulation, myofascial release, craniosacral therapy, as monotherapy or adjunctive therapies in older people (age ≥65 years) with musculoskeletal disorders. …”
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