ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans. by Lina Zhao, Lorenz A Fenk, Lars Nilsson, Niko Paresh Amin-Wetzel, Nelson Javier Ramirez-Suarez, Mario de Bono, Changchun Chen

“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
Get full text

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. by Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota

“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
Get full text

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
Get full text

Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
Get full text

Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction. by Takeshi Matsui, Ian M Ehrenreich

“…To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two budding yeast strains. This phenotype is detectable when certain segregants are grown on ethanol at 37°C ('E37'), a condition that differs from the standard culturing environment in both its carbon source (ethanol as opposed to glucose) and temperature (37°C as opposed to 30°C). …”
Get full text

Real-World Efficacy of Explainable Artificial Intelligence using the SAGE Framework and Scenario-Based Design by Eleanor Mill, Wolfgang Garn, Chris Turner

“…The first of its kind, it leverages three distinct but complementary frameworks to support a user-centric and context-sensitive, post-hoc explanation for fraud detection. Using the principles of scenario-based design, it amalgamates two independent real-world sources to establish a realistic card fraud prediction scenario. …”
Get full text

Venous Thromboembolism Prophylaxis in Intensive Care Units (Review) by L. V. Popova, T. B. Kondratieva, M. Z. Kanevskaya, T. L. Aleinikova, E. S. Zykova, А. V. Krivova, A. M. Kuznetsov

“…VTE is common and potentially life-threatening in patients admitted to ICU, even in spite of preventive care.The purpose of the review is to justify the necessity of preventive care for venous thromboembolism in ICU patients.From over 300 initially selected sources of literature databases (Scopus, Web of science, RSCI, etc.), 99 sources were chosen including 69 that were published during the last five years (2015-2020). …”
Get full text

Treatment outcomes and associated factors of stroke in Ethiopia: a systematic review and meta-analysis by Addisu Getie, Shirin Jahan Mumu, Amit Arora

“…Subgroup analysis, meta-regression, and sensitivity analysis were computed to investigate the source of heterogeneity. A log odds ratio was employed to ascertain the association between poor (stroke patients who died or were discharged with significant functional and structural dysfunction) stroke treatment outcomes and associated factors. …”
Get full text

Implementation of stochastic signal processing algorithms in radar CAD by M. Yu. Konopel'kin, S. V. Petrov, D. A. Smirnyagina

“…A simulation model of a sector surveillance radar with a digital antenna array was created in the radar CAD visual functional editor. The passive channel included the following algorithms: algorithm for detecting stochastic signals; algorithm for estimating the number of stochastic signals; direction finding algorithm for stochastic signal sources; adaptive spatial filtering algorithm. …”
Get full text

Association of Omega-3 Index and Blood Cell Count-Derived Systemic Inflammatory Indexes among Testicular Germ Cell Tumor Survivors by Milica Zeković, Marko Živković, Marija Takić, Sanja Stanković, Nebojša Bojanić, Aleksandar Janičić, Uroš Bumbaširević

“…Background and objectives: Although testicular cancer is considered the paradigm of highly curable malignancy, treatment-induced adverse effects and potential impairment of gonadal function may cause non-negligible long-term health repercussions, including metabolic disturbances and cardiovascular sequelae. …”
Get full text

The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
Get full text

Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
Get full text

Probing Cosmic Isotropy with the FAST All Sky H i Survey by Yi-Wen Wu, Jun-Qing Xia

“…To mitigate the potential influence of spurious clustering effects due to these sensitivity variations, we focus on extragalactic H i sources within the sensitivity range of [0.65, 1.0]. …”
Get full text

Synovial cesys in children: clinical features, diagnostics, treatment (analytical review of the literature and own observation) by V.S. Konoplitskyi, Yu. Ye. Korobko, B.L. Pavlenko, H.M. Rudenko, O.A. Korobko, S.V. Klymenko

“…Thus, according to literature sources, the frequency of pathology in patients under 20 years of age reaches 10% in the population and less than 2% in children under 10 years of age. …”
Get full text

Comparative genomics reveals key adaptive mechanisms in pathogen host-niche specialization by Menglu Zhang, Longxi Han, Caizhi Liao, Weiheng Su, Weiheng Su, Chunlai Jiang, Chunlai Jiang

“…In contrast, bacteria from environmental sources, particularly those from the phyla Bacillota and Actinomycetota, showed greater enrichment in genes related to metabolism and transcriptional regulation, highlighting their high adaptability to diverse environments. …”
Get full text

Digital Twin-Based Technical Research on Comprehensive Gear Fault Diagnosis and Structural Performance Evaluation by Qiang Zhang, Zhe Wu, Boshuo An, Ruitian Sun, Yanping Cui

“…The advantage of the research lies in the interaction and visualization of fusion of multi-source data, but it is limited to the accuracy of finite element simulation and the difficulty of obtaining actual stress data. …”
Get full text

Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media by Humaira Yasmin, Rawan Bossly, Fuad S. Alduais, Afrah Al-Bossly, Anwar Saeed

“…The greater magnetic, Brownian motion, heat source, thermal radiation factors, and thermophoresis factors have increased the heat transfer rate. …”
Get full text

On path length, beam divergence, and retroreflector array size in open-path FTIR spectroscopy by C. E. N. Power, C. E. N. Power, A. Wiacek, A. Wiacek

“…<p>Open-path Fourier transform infrared (OP-FTIR) spectroscopy is an established technique used to measure boundary layer trace gas concentrations, consisting (in this work) of a spectrometer with an active mid-IR source coupled to a single transmitting and receiving telescope, as well as a cube-corner retroreflector array separated from the spectrometer and telescope by an atmospheric path. …”
Get full text

Complexation with Alginate in Pumpkin Leaf Protein Solutions for the Encapsulation of Folic Acid: The Effect of Extraction Protocols by Predrag Petrović, Bojana Balanč, Jelena Mijalković, Tamara Đukić, Stefan Bošković, Verica Đorđević, Branko Bugarski, Viktor Nedović, Zorica Knežević-Jugović

“…This study aimed to assess pumpkin leaves as a protein source and determine the feasibility of these proteins to form complexes with alginate for the encapsulation of folic acid. …”
Get full text

A new fluorescent probe based on BODIPY for testing NO2 released from propellants by Ying-cui Cui, De-bin Xia, Zhong-yu Cui, Yu-jing Li, Jian Zhang, Ping Wang, Ting Guo, Kai-feng Lin, Yu-lin Yang

Get full text