Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§ by Nita Kaushik, Aradhita Barmanray

“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
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Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…All the patients underwent chest computed tomography (CT). When detecting CT changes, we performed fibrobronchoscopy (FBS) with microbiological examination of bronchoalveolar lavage (BAL).Results. …”
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Biomechanical Changes to the Ankle After Zadek Osteotomy by Nicholas Bellas MD, Raghunandan Nayak BS, Mehreen Pasha BS, Megan R. Wolf MD, Elifho Obopilwe MS, Thomas McDonald MD, Lauren E. Geaney MD

“…Category: Hindfoot; Sports Introduction/Purpose: Insertional Achilles tendinopathy is a common source of heel pain in active adults and athletes. …”
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Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach by Zhengyuan Su, Huadong Jiang, Ying Yang, Xiangqing Hou, Yanli Su, Li Yang

“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
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Estimating the mass of tephra accumulated on roads to best manage the impact of volcanic eruptions: the example of Mt Etna, Italy by L. Mereu, L. Mereu, M. Stocchi, M. Stocchi, A. Garcia, M. Prestifilippo, L. Sandri, C. Bonadonna, S. Scollo

“…First, we analysed a sequence of 39 short-lasting and intense lava fountains detected by the X-band weather radar, applying a volcanic ash radar retrieval approach that permits us to compute the main eruption source parameters (ESPs), such MER, <span class="inline-formula"><i>H</i>_TP</span>, and GSD. …”
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Analysis of genomic selection characteristics of local cattle breeds in Gansu by Bao Cai, Yandong Kang, Lin Xiong, Jie Pei, Qianyun Ge, Xiaoyun Wu, Manyu Gan, Xian Guo

“…It provides a theoretical basis for conserving breed resources, identifying functional genes, and developing breeding strategies.…”
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Positioning, navigation, and timing on the Moon and Mars with galactic cosmic rays by G. Leone, H.K.M. Tanaka, M. Holma, S. Krishnan, A.R. Duffy, T. Enqvist, P. Kuusiniemi, J. Joutsenvaara, G. Cerretto, E. Cantoni, M. Sellone, J. Marteau, D. Lo Presti, J.G. Szűcs, D. Varga

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A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention by You Zhai, Hongcai Shang, Yan Li, Nan Zhang, Jisi Zhang, Shangwen Wu

“…ObjectiveThis study aims to systematically review the risk factors for major adverse cardiovascular events (MACE) in patients with coronary heart disease who have undergone percutaneous coronary intervention (PCI).DesignSystematic review and meta-analysis.Data sourcesThe Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals (VIP) were screened until December 2024.Eligibility criteria for selecting studiesCase-control studies or cohort studies on the risk factors for MACE in patients with coronary heart disease who underwent PCI. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c &gt;7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda. by Jonathan Kitonsa, Onesmus Kamacooko, Ubaldo Mushabe Bahemuka, Freddie Kibengo, Ayoub Kakande, Anne Wajja, Vincent Basajja, Alfred Lumala, Edward Ssemwanga, Robert Asaba, Joseph Mugisha, Benjamin F Pierce, Robin Shattock, Pontiano Kaleebu, Eugene Ruzagira

“…Data were analysed descriptively and a binomial generalised linear model with a log link function used to investigate factors associated with unwillingness to participate.…”
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Sensory integration research: priority scientific directions based on the analysis of Web of Science Core Collection resources by Olha Podrihalo, Wladyslaw Jagiello, Guo Xiaohong, Leonid Podrigalo, Tetiana Yermakova, Miroslawa Cieslicka

“…The bibliometric database Web of Science Core Collection (WoS) was analyzed. 388 sources that met the search criteria for 2013-2023 were selected for primary analysis. …”
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Persistence in the socio-economic development of the regions of the Siberian Federal District by Misak S. Arzumanyan

“…The term «persistence» originally has a biological and medical origin, as a property of microorganisms (bacteria, viruses) to survive and function in an aggressive environment (e.g., when exposed to antibiotics). …”
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Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

“…The target bacterial isolate was detected in medfly when inoculated with liquid diet regardless of age, but those fed a slurry-based diet and a separate water source had less establishment. …”
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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

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An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment by Enzo Romero, Jose G. Garcia, Magno Parra, Sebastian Caballa, Alejandro M. Saldarriaga, Edson F. Luque, Dante J. Rodriguez, Victoria E. Abarca, Dante A. Elias

“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
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Establishment and characterization of liver‐specific Apoa4‐Cre and Cyp2c11‐Cre rat models in juvenile and adult stages by Wei Dong, Xiang Gao, Feifei Guan, Jirong Pan, Wei Chen, Li Zhang, Lianfeng Zhang

“…The use of floxed rat resource has rapidly increased, but the liver‐specific Cre rat lines for studying liver diseases and interested genes are limited, especially in a spatially and temporally restricted manner. …”
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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…In MCI, early serotonergic dysregulation involving SERT occurs before detectable atrophy.…”
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In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu... by Evangelia N. Kerezoudi, Marigoula Vlassopoulou, Evdokia K. Mitsou, Georgia Saxami, Georgios Koutrotsios, Ioanna Taflampa, Konstantinos C. Mountzouris, Ignacio Rangel, Robert J. Brummer, Georgios I. Zervakis, Vasiliki Pletsa, Panagiotis Georgiadis, Adamantini Kyriacou

“…The changes in bacterial communities upon fermentation at family, genera and species level were detected via 16S rRNA Next Generation Sequencing and Quantitative real-time PCR. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development by Tingting Zhou, Ningbo Huangfu, Li Wang, Junyu Luo, Jinjie Cui, Xiangzhen Zhu, Sumei Wan, Xueke Gao

“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging by Hong-Fei Li, Bao Dong, Yuan-Yuan Peng, Hao-Yue Luo, Xiao-Lan Ou, Zheng-Lin Ren, Yoonseong Park, Jin-Jun Wang, Hong-Bo Jiang

“…Further analysis of the mutant flies revealed that sets of odorant receptor (OR) genes were differentially expressed. Functional characterization of the differentially expressed ORs suggested that sulfakinin directly suppresses the expression of ORs that respond to opposite-sex hormones while enhancing the expression of ORs that detect food volatiles. …”
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