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Genome-wide identification and expression pattern analysis of NAC family in Taxus yunnanensis and the TyuNAC30 role in paclitaxel production
Published 2025-07-01“…Yeast one-hybrid and related assays revealed that TyuNAC30 functions as a negative regulator of TyuDBTNBT, a key enzyme gene in the paclitaxel biosynthetic pathway. …”
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1544
An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment
Published 2025-01-01“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
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circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p
Published 2022-01-01“…Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers, accounting for around 80% of total lung cancer cases worldwide. Exploring the function and mechanism of circRNAs could provide insights into the diagnosis and treatment for NSCLC. …”
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1547
Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review
Published 2025-05-01“…The main literature searches were then conducted using six databases: Applied Social Sciences Index and Abstracts (ProQuest), Cumulative Index to Nursing and Allied Health Literature (EBSCO), MEDLINE (Ovid), PsycInfo (Ovid), EMBASE (Ovid) and Web of Science Core Collection (Emerging Sources Citation Index). The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. …”
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In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu...
Published 2025-06-01“…The changes in bacterial communities upon fermentation at family, genera and species level were detected via 16S rRNA Next Generation Sequencing and Quantitative real-time PCR. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development
Published 2025-08-01“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging
Published 2025-05-01“…Further analysis of the mutant flies revealed that sets of odorant receptor (OR) genes were differentially expressed. Functional characterization of the differentially expressed ORs suggested that sulfakinin directly suppresses the expression of ORs that respond to opposite-sex hormones while enhancing the expression of ORs that detect food volatiles. …”
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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro
Published 2024-12-01“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT
Published 2025-05-01“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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Additive Manufacturing for Automotive Radar Sensors Using Copper Inks and Pastes
Published 2025-03-01“…Radar sensors are critical for obstacle detection and navigation, especially for automated driving. …”
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IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images
Published 2025-05-01“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin
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A Benzimidazole-Based Fluorescent Probe for the Selective Recognition of Cobalt (II) Ions
Published 2025-08-01“…However, excessive cobalt intake can cause health issues. Detecting cobalt ions, especially Co<sup>2+</sup>, in food is crucial due to potential contamination from various sources. …”
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