Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors by Daniel J. Merk, Foteini Tsiami, Sophie Hirsch, Bianca Walter, Lara A. Haeusser, Jens D. Maile, Aaron Stahl, Mohamed A. Jarboui, Anna Lechado-Terradas, Franziska Klose, Sepideh Babaei, Jakob Admard, Nicolas Casadei, Cristiana Roggia, Michael Spohn, Jens Schittenhelm, Stephan Singer, Ulrich Schüller, Federica Piccioni, Nicole S. Persky, Manfred Claassen, Marcos Tatagiba, Philipp J. Kahle, David E. Root, Markus Templin, Ghazaleh Tabatabai

“…Results We here use a functional genomics approach to identify genetic dependencies in ATRT, validate selected hits using a functionally instructed small molecule drug library, and observe preferential activity in ATRT cells without subgroup-specific selectivity. …”
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Structural and functional properties of bacterial communities associated with rootless duckweed (Wolffia globosa) and their effect on the Wolffia growth by Yuparat Saimee, Kousuke Kuwai, Hidehiro Ishizawa, Daisuke Inoue, Arinthip Thamchaipenet, Michihiko Ike

“…Abstract Background Rootless duckweed, Wolffia globosa, is emerging as a high-protein and starch biomass resource for various applications. However, the microbiomes and functional properties associated with Wolffia across a wide range of microbial sources remain largely unexamined. …”
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Loss of OprD function is sufficient for carbapenem-resistance-only but insufficient for multidrug resistance in Pseudomonas aeruginosa by Maofeng Wang, Yuxiao Zhang, Fengyan Pei, Ying Liu, Yan Zheng

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Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study. by Carolyn A Carr, Daniel J Stuckey, Jun Jie Tan, Suat Cheng Tan, Renata S M Gomes, Patrizia Camelliti, Elisa Messina, Alessandro Giacomello, Georgina M Ellison, Kieran Clarke

“…<h4>Aims</h4>Endogenous cardiac progenitor cells, expanded from explants via cardiosphere formation, present a promising cell source to prevent heart failure following myocardial infarction. …”
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Combining Open-Source Machine Learning and Publicly Available Aerial Data (NAIP and NEON) to Achieve High-Resolution High-Accuracy Remote Sensing of Grass–Shrub–Tree Mosaics by Brynn Noble, Zak Ratajczak

“…NAIP underperformed in detecting evergreen trees (52–78% vs. 83–86% accuracy with NEON). …”
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Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome by Jun-Jie Li, Qing Yao, Ming Dong, Yan Wang, Ye Xiu, Zhi-Xin Wu, Xiao-Mei Zhao, Yin-Kang Wang, Xian-Ling Wang, Yu-Xuan Tian, Xiao-He Xiao, Zhao-Fang Bai

“…Materials and Methods: The activation of the cGAS-STING pathway was modeled in bone marrow-derived macrophages (BMDMs) and human leukemia monocytic cell line (THP-1) cells in vivo, and the expression of type I IFN-related genes and pro-inflammatory cytokines was detected after DG pretreatment. Next, we examined the effect of DG on STING downstream signaling events, such as STING oligomerization and functional STING signalosome formation. …”
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Physiological, biochemical and genetic bases of amaranth (Amaranthus L.) breeding for food and feed purposes (a review) by A. B. Shcherban

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Combination of Cu-BTC- and FeCo-MOF-Derived Carbon Enhanced Molecularly Imprinted Electrochemical Sensor for Highly Sensitive and Selective Detection of Benomyl in Fruits and Veget... by Lili Chen, Shuya Xue, Xin Li, Linbo Deng, Jiapeng Li, Jing Zhou, Yansha Gao, Xuemin Duan, Limin Lu

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Selective Manganese Precipitation via Neutralization and Ozone Oxidation under pH Conditions Similar to Steel Pickling Wastewater: Thermodynamic Assessment and Experimental XANES E... by Mauricio Córdova-Udaeta, Bowen Cheng, Shigeshi Fuchida, Yutaro Takaya, Jun Horiuchi, Hiroyuki Masuoka, Keishi Oyama, Chiharu Tokoro

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DETERMINATION OF THE OPTIMAL DISTRIBUTION OF SUPPORTS IN THE FLOOR SLABS OF IN-DUSTRIAL BUILDINGS USING STOCHASTIC METHODS by E. A. Efimenko, M. Yu. Bekkiev, D. R. Mayilyan, A. S. Chepurnenko

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Generalized Formalization Related Signs of Functioning Ergo Technical Information Electronic Systems on the Basis of Their Structural and Logical Models by A. N. Potapov

“…The possibility of implementation of the RES functions selection, allocation and reallocation of resources depend on its inherent mechanisms of control. …”
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Context-dependent PSIICOS: A novel framework for functional connectivity estimation accounting for task-related power leakage by Daria Kleeva, Alexei Ossadtchi

“…The results demonstrate that CD-PSIICOS outperforms the original PSIICOS in suppressing artifacts at the lower projection ranks, maintaining robust detection of functional networks across theta and gamma frequency bands. …”
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Metabolic Mechanism of Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cell Regulated by Magnetoelectric Microenvironment by Han Zhao, Fangyu Zhu, Yusi Guo, Xuliang Deng, Wenwen Liu

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Soil function, properties and plant diversity–biomass patterns differ between grazed and non-grazed steppe ecosystems by Jia Mi, Jia Mi, Qianju Wang, Jun Ou, Jing Shi, Haiyan Pang, Ziheng Feng, Yongfei Bai, Yongfei Bai

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Hybrid Framework To Exclude Similar and Faulty Test Cases In Regression Testing by Muhammad Asim Siddique, Wan M.N. Wan-Kadir, Johanna Ahmad, Noraini Ibrahim

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Research on the Suitability Evaluation and Enhancement Path of Grassland Ecological Product Value Transformation in China Based on the Three-Dimensional Evaluation Matrix of Ecolog... by Yaojie Wu, Pengwei Chen, Li Ma

“…In the future, resource and policy allocation could lead to regionally coordinated development.…”
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SILVERRUSH. XIV. Lyα Luminosity Functions and Angular Correlation Functions from 20,000 Lyα Emitters at z ∼ 2.2–7.3 from up to 24 deg2 HSC-SSP and CHORUS Surveys: Linking the Postr... by Hiroya Umeda, Masami Ouchi, Satoshi Kikuta, Yuichi Harikane, Yoshiaki Ono, Takatoshi Shibuya, Akio K. Inoue, Kazuhiro Shimasaku, Yongming Liang, Akinori Matsumoto, Shun Saito, Haruka Kusakabe, Yuta Kageura, Minami Nakane

“…We present luminosity functions (LFs) and angular correlation functions (ACFs) derived from 18,960 Ly α emitters (LAEs) at z  = 2.2−7.3 over a wide survey area of ≲24 deg ^2 that are identified in the narrowband data of the HSC-SSP and CHORUS surveys. …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…Information required to populate the models included the prevalence of lung nodules, risk of lung cancer with different nodule sizes, sensitivity and specificity for nodule detection, nodule type and size distributions in different population, resource use, costs and utilities. …”
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A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles by Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger

“…Subsequently, adding gold nanoparticles functionalized with SERS probes and aptamers enabled the detection of tau in EVs using SERS. …”
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First Stability Characterization for a CZT Detection System in an e⁺e⁻ Collider Environment by Leonardo Abbene, Francesco Artibani, Manuele Bettelli, Antonino Buttacavoli, Fabio Principato, Andrea Zappettini, Massimiliano Bazzi, Giacomo Borghi, Mario Bragadireanu, Michael Cargnelli, Marco Carminati, Alberto Clozza, Francesco Clozza, Luca De Paolis, Raffaele Del Grande, Kamil Dulski, Laura Fabbietti, Carlo Fiorini, Carlo Guaraldo, Mihail Iliescu, Masahiko Iwasaki, Aleksander Khreptak, Simone Manti, Johann Marton, Pawel Moskal, Fabrizio Napolitano, Szymon Niedźwiecki, Hiroaki Ohnishi, Kristian Piscicchia, Yuta Sada, Francesco Sgaramella, Diana Laura Sirghi, Florin Sirghi, Magdalena Skurzok, Michal Silarski, Antonio Spallone, Kairo Toho, Lorenzo Toscano, Marlene Tüchler, Oton Vasquez Doce, Johann Zmeskal, Catalina Curceanu, Alessandro Scordo

“…Additionally, this study introduces a validated model of the response function of the detector. The relative deviations from the nominal values for the source transitions, obtained by fitting the entire spectrum with a background function and the previously introduced response function, are reported. …”
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