Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…In conclusion, our results provide the immune landscape of necrotizing granulomas and reveal novel functional states of macrophages contributing to TB pathogenesis.…”
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The Structure of the Methodology "Motivation for the Adoption of an Orphan Child by a Foster Family" by Oslon V.N., Odintsova M.A., Semya G.V., Kolesnikova U.V.

“…The methodology "Motivation for the adoption of an orphan child by a foster family" is capable of performing a prognostic function and can be used by specialists of the SPR to select resource replacement families for an adopted child, as well as to track the dynamics of changes in motivation in the process of preparing potential foster parents, actualization and mobilization of types of motivation adequate to the tasks of raising an orphan child, neutralization and correction of the inadequate ones.…”
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Assessment of disease impact through health‐related quality of life measurement in primary progressive aphasia by Thomas Hopkins, Eunbi Kwon, Allison Lapins, Nathan Gill, Angela Roberts, Emily Rogalski

“…Language severity scores showed significant associations with HUI multi‐attribute scores and select single‐attribute measures (hearing, sensation, cognition, and speech) with less language impairment associated with better functional capacity related to HRQoL. …”
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Comparison of Methods for Isolation and Characterization of Total and Astrocyte‐Enriched Extracellular Vesicles From Human Serum and Plasma by Leandra K. Figueroa‐Hall, Kaiping Burrows, Ahlam M. Alarbi, Bethany N. Hannafon, Cole Hladik, Chibing Tan, Rajagopal Ramesh, Jennifer L. Stewart, Victoria B. Risbrough, Martin P. Paulus, T. Kent Teague

“…This study provides a comprehensive resource for researchers in selecting EV isolation methods tailored to small biobanked clinical samples, with the goal of advancing biomarker discovery in Neuroscience.…”
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Assessing the risk spillover effects between the Chinese carbon market and the US-China energy market by Jiale Yan, Cem Işık

“…This paper uses the optimal ARMA-GARCH to fit the marginal distribution of each market and selects the optimal Copula function for the calculation of CoVaR to obtain more accurate risk measurement results. …”
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Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh by Sharmin Sultana, Md Shamsuzzaman, Md. Abdus Satter Miah, Akhter Jahan Kakon, Abdullah Hel Mafi, Anupoma Sen, Md. Nurealam Siddiqui, Debu Kumar Bhattacharjya

“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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The role of paramedics in emergency medical teams responding to natural disasters: a scoping review by Estelle C. Seton, Tom Mallinson, Carl A. Webster

“…RESULTS: Analysis of the selected studies revealed four prominent themes: operational and access challenges, healthcare delivery and infrastructure, communication and data management, and resource utilisation and team management. …”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals by Edanur Güler–Ekmen, İsmail Çağrı Yılmaz, Talat Güler, Derya Güler, Mehtap Özçelik

“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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Features of the alpha-cell population organization in pancreas of spontaneously hypertensive rats (SHR) by T. V. Abramova, Yu. M. Kolesnyk

“…At the same time, glucagon-suppressive therapy is defined as the strategically main source of success of therapy for patients with type 2 diabetes mellitus. …”
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MULTI-MODEL STACK ENSEMBLE DEEP LEARNING APPROACH FOR MULTI-DISEASE PREDICTION IN HEALTHCARE APPLICATION by Bhaskar Adepu, T. Archana

“…These datasets serve two functions: improving illness prediction and examining large data reservoirs to identify previously unknown disease patterns. …”
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Substandard Language Phenomena in Artistic Discourse by Anzhelika V. Korolkova, Tatyana S. Novikova

“…The modern language substandard implements various functions in literary texts, from nominative to cognitive and cumulative, from the expression of emotions to vivid evaluativeness. …”
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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. by Michele Vacca, Simona D'Amore, Giusi Graziano, Andria D'Orazio, Marica Cariello, Vittoria Massafra, Lorena Salvatore, Nicola Martelli, Stefania Murzilli, Giuseppe Lo Sasso, Renato Mariani-Costantini, Antonio Moschetta

“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection. by Alex J McCarthy, David Negus, Patricia Martin, Catarina Pechincha, Eric Oswald, Richard A Stabler, Peter W Taylor

“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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Pan-genome analysis of the R2R3-MYB genes family in Brassica napus unveils phylogenetic divergence and expression profiles under hormone and abiotic stress treatments by Haiyan Fan, Haiyan Fan, Jiawei Li, Jiawei Li, Wencong Huang, Aoshuang Liang, Liqing Jing, Jintao Li, Qing-Yong Yang, Qing-Yong Yang, Kede Liu, Zhiquan Yang

“…However, their genetic diversity and functional roles in Brassica napus remain underexplored at a pan-genome scale.MethodsWe identified R2R3-MYB genes in 18 published rapeseed genomes and analyzed their genomic distribution patterns, gene duplication, selective pressure, gene structure, conserved motifs, and phylogenetic relationships using a pan-genome approach. …”
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Discriminant analysis of variational pulsometry parameters by U. I. Silkina, V. A. Balandin

“…The parameters with weak cross-correlation with high predictive significance, the spread of the values of which corresponds to the normal distribution law, were selected for the discriminant analysis. A function which allows to identify the patient as “sick” or “healthy” (one of the categories) has been determined. …”
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IT GOVERNANCE IN THE BANKING SECTOR: EVIDENCE FROM ITALY, GERMANY, FRANCE AND SPAIN by Ida Claudia Panetta, Sabrina Leo, Fabrizio Santoboni, Gianfranco Vento

“…IT is an intrinsic component of banks’ operational functioning; it is a key resource in developing and supporting banking services, enabling institutions’ strategies, and it is essential for almost all banking processes and distribution channels. …”
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Polycentric governance: Evaluating the relevance of traditional authorities in good governance in South Africa by Samson Faboye, Trynos Gumbo, Jackson Sebola

“…The study argues that good governance is defined by its ability to meet the needs of the broader populace, not simply select groups. It proposes a formalised polycentric governance framework that elevates traditional authorities as key actors in local government, with a focus on areas such as administrative hierarchy, development planning, land governance, and natural resource management. …”
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The Genome Assembly of Vitis vinifera cv. Shiraz by Cristobal A. Onetto, Christopher M. Ward, Anthony R. Borneman

“…Long-read ONT data were selected to produce a highly contiguous genome assembly for Shiraz. …”
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