A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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The Role of Circulating Biomarkers in Patients with Coronary Microvascular Disease by Rossella Quarta, Giovanni Martino, Letizia Rosa Romano, Giovanni Lopes, Francesco Fabio Greco, Carmen Anna Maria Spaccarotella, Ciro Indolfi, Antonio Curcio, Alberto Polimeni

“…Coronary microvascular disease (CMD) comprises a spectrum of conditions characterized by the functional and structural abnormalities of coronary microcirculation, affecting vessels typically smaller than 500 μm. …”
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ICP Enhancement Algorithm for 6D Pose Tracking of Household Objects by Hyunho Hwang, Hyunsoo Shin, Ji-Hun Bae, Sungon Lee

“…We estimate the initial pose using RGB keypoints and fine-tune the weights of the loss function to achieve an accurate pose by considering the flat and rotational symmetric properties of the object. …”
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Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

“…Emerging strategies, such as selective NOX inhibitors, antioxidant therapies, and agents modulating signaling transduction, offer promising avenues for mitigating oxidative injury and improving cardiac function. …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…One-third of the included studies used the leaves of the selected plants. The reviewed studies highlighted neuroprotective activities of the plants, as evidenced by biochemical and behavioral improvements. …”
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Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34+ Cells by Dorian Forte, Daria Sollazzo, Martina Barone, Marisole Allegri, Angela di Martella Orsi, Marco Romano, Barbara Sinigaglia, Giuseppe Auteri, Nicola Vianelli, Michele Cavo, Francesca Palandri, Lucia Catani

“…Taken together, these data indicate that combined proinflammatory stimuli promote distinct in vitro functional activation of neonatal or adult normal HSPCs.…”
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A Study on the Influence Mechanisms of Neighborhood Vitality and the Characteristics of Spatial and Temporal Differentiation in the Urban Fringe Areas of Wuhan City by Yan Long, Siyu Hu, Zhengyuan Lu, Lianghao Cheng, Cairui Zhen, Jingmei Shao, Yuqiao Zheng, Xuehui Zhou, Jin Li, Yudi Lin, Shu Zhang, Yue Wang, Tianyue Luo, Haijuan Zhao, Xuejun Liu

“…This paper quantifies the neighborhood vitality of the fringe areas by the short-stay visitors in the fringe areas and selects the 5D elements of the built environment and social media data from multiple sources to construct the indicator system assessing the neighborhood vitality of the urban fringe areas. …”
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Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. by Corinne Kostic, Simon Geoffrey Lillico, Sylvain Vincent Crippa, Nicolas Grandchamp, Héloïse Pilet, Stéphanie Philippe, Zen Lu, Tim James King, Jacques Mallet, Chamsy Sarkis, Yvan Arsenijevic, Christopher Bruce Alexander Whitelaw

“…Sixty percent of the piglets were transgenic, with mutant GUCY2D mRNA detected in the retina of all animals tested. Functional impairment of vision was observed among the transgenic pigs at 3 months of age, with a follow-up at 1 year indicating a subsequent slower progression of phenotype. …”
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Recent Advances in Understanding the Keys Factors Influencing Pressurized Liquid Extraction of Secondary Metabolites: A Comprehensive Review by Pauline Donn, Sepidar Seyyedi-Mansour, Franklin Chamorro, Paula Garcia-Oliveira, Javier Echave, Ana Perez-Vazquez, Paula Barciela, Lucia Cassani, Miguel Angel Prieto

“…., phenolic compounds) from botanical sources, with implications spanning across pharmaceuticals, nutraceuticals, and functional foods. …”
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The Effectiveness of Exercise Interventions Supported by Telerehabilitation For Recently Hospitalized Adult Medical Patients: A Systematic Review by Simone Leslie, Junmin Tan, Prudence J. McRae, Shaun P. O'Leary, Julie A. Adsett

“…Methods: Studies were selected if they included an exercise intervention for recently hospitalized adults, delivered by a physiotherapist via videoconference. …”
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Controllable surface carrier type of metal oxide nanocrystals for multifunctional photocatalysis by Han Li, Yingchun Ding, Kaiyi Luo, Qiuping Zhang, Huan Yuan, Shuyan Xu, Ming Xu

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Neuropsychiatric Manifestations of Lyme Disease: A Literature Review of Psychiatric and Cognitive Impacts by Gabija Šegždaitė, Odeta Aliukonytė, Kamilė Pociūtė

“…This paper examines the connection between Lyme disease and neuropsychiatric outcomes to improve diagnosis and treatment.Materials and Methods: The PubMed database was searched for scientific literature sources. Publications published in English in 2019–2024 were selected. …”
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Thermodynamics of interaction of inulin complex with water by Yu. A. Maksimenko, O. I. Konnova, I. Yu. Aleksanian

“…Currently, the key trends in the global food market include the rapidly developing functional nutrition industry, which is of great interest to consumers. …”
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Degradation of extracellular polymeric substances shapes microbial community diversity. by Sammy Pontrelli, Kian Bigovic Villi, Andreas Sichert, Julian Trouillon, Adriano Rutz, Zachary C Landry, Simon H Rüdisser, Roman Stocker, Uwe Sauer

“…EPS was produced at similar levels across marine chitin-degrading isolates and seawater communities, underscoring its importance relative to small metabolites. Notably, different sources of EPS were found to select for distinct and diverse microbial communities. …”
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Antimicrobial Potential of Extract from a Pseudomonas aeruginosa Isolate by Francis Kwaku Dzideh Amankwah, Stephen Yao Gbedema, Yaw Duah Boakye, Marcel Tunkumgmen Bayor, Vivian Etsiapah Boamah

“…Microorganisms are one of the main sources of antimicrobial agents and over 50% of antibiotics currently used in hospitals are metabolites from microbes. …”
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Candidate gene identification and marker development for seed coat peeling rate in peanut (Arachis Hypogaea L.) by Hongfei Liu, Ziqi Sun, Feiyan Qi, Xiao Wang, Meng Zhang, Juan Wang, Xiaobo Wang, Ziqiang Mo, Mingbo Zhao, Chenyang Zhi, Mengmeng Wang, Zhiyuan Zhou, Linhong Xu, Wenzhao Dong, Zheng Zheng, Xinyou Zhang

“…Furthermore, a functional marker A05.114993389 was developed and validated in both the natural and RIL populations, providing a valuable genomic resource for marker-assisted selection (MAS) in peanut breeding programs. …”
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Ocular Toxicity Associated with Tamoxifen Administration in Patients with Breast Cancer: A Systematic Review by Tejaswi Vadde, Neha Narayan, Amulya Varshini Banka, Shravani Divity, Yethindra Vityala

“…Introduction: Tamoxifen (TAM), a selective Oestrogen Receptor (ER) modulator, is widely used for treating and preventing ER-positive Breast Cancer (BC). …”
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Effect of zeolites modification on their adsorption properties by L. G. Eprikashvili, T. N. Kordzakhia, M. G. Zautashvili, N. V. Pirtskhalava, M. A. Dzagania, G. P. Tsintskaladze, T. V. Sharashenidze

“… Atmospheric air pollution is determined by the functioning of both technogenic and natural sources of pollution. …”
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Linguistic Features of the Ergonomic Space of the Central Streets of Yoshkar-Ola and Kazan by Iraida G. Ivanova, Flera Ya. Khabibullina

“…Urbanonyms as names of objects of various functional profiles are an indicator of preferred languages for naming urban objects, and act as a marker of the spheres of functioning of languages in a given territory. …”
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Presenting the Physical Pattern of Today's Housing by Taking Advantage of the Desirable Qualities of Historical Houses (Case Study: Kerman City) by Amjad Bahredar, Ramin Madani, Mohsen Afshari

“…These qualities, in addition to meeting their functional needs, seek to solve the superior needs of the residents. …”
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