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841
Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution.
Published 2009-05-01“…This mechanism has duplicated hundreds of sequences predicted to be functional in the human genome, including exons, UTRs, intron splice sites and transcription factor binding sites. …”
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842
Devicology: Expanding fieldwork possibilities for architectural observations in inhabited interiors
Published 2022-04-01“…These visually chaotic yet surprisingly functional structures are the only tool of the current dwellers to negotiate with the restricting standard apartment plans that were originally designed for a very different sector of the Japanese population. …”
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843
Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains
Published 2025-06-01“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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844
A survey on the applications of transfer learning to enhance the performance of large language models in healthcare systems
Published 2025-06-01“…This research analyzes different transfer learning methods, including inductive, transductive, and unsupervised techniques, while demonstrating their effectiveness in detecting COVID-19 from chest X-rays and multi-source disease evaluation. …”
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845
Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability
Published 2024-10-01“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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846
Current status of transcriptome sequencing technology in ruminants
Published 2025-06-01“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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847
User Communities — Drivers for Open Innovation
Published 2014-03-01“…Users best judge what will lead to commercial success, and they have long been recognized as a valuable source of knowledge to harvest for future innovation. …”
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848
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849
Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques
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850
Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice
Published 2025-08-01“…In conclusion, our results provide the immune landscape of necrotizing granulomas and reveal novel functional states of macrophages contributing to TB pathogenesis.…”
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851
Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh
Published 2024-11-01“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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852
Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis
Published 2022-01-01“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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853
The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals
Published 2025-08-01“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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854
Features of the alpha-cell population organization in pancreas of spontaneously hypertensive rats (SHR)
Published 2017-08-01“…At the same time, glucagon-suppressive therapy is defined as the strategically main source of success of therapy for patients with type 2 diabetes mellitus. …”
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855
MULTI-MODEL STACK ENSEMBLE DEEP LEARNING APPROACH FOR MULTI-DISEASE PREDICTION IN HEALTHCARE APPLICATION
Published 2025-03-01“…These datasets serve two functions: improving illness prediction and examining large data reservoirs to identify previously unknown disease patterns. …”
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856
Substandard Language Phenomena in Artistic Discourse
Published 2025-12-01“…The modern language substandard implements various functions in literary texts, from nominative to cognitive and cumulative, from the expression of emotions to vivid evaluativeness. …”
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857
HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors
Published 2025-07-01“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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858
Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma.
Published 2014-01-01“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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859
Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection.
Published 2016-01-01“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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860
Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China
Published 2024-11-01“…Paddy fields are the main agricultural source of greenhouse gas methane (CH<sub>4</sub>) emissions. …”
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