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LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION
Published 2015-03-01“…Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.…”
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Estimating fish stock biomass using a Bayesian state-space model: accounting for catchability change due to technological progress
Published 2024-12-01“…This model allows for the flexible integration of the timing and functional form of the uptake of technological innovations that are assumed to influence catchability. …”
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Survey on Backdoor Attacks on Deep Learning: Current Trends, Categorization, Applications, Research Challenges, and Future Prospects
Published 2025-01-01“…Such attacks are usually referred to as Trojan or backdoor attacks and are very stealthy and hard to detect. In this paper, we highlight the complete attack surface that can be exploited to inject hidden malicious functionality (backdoors) in machine learning models. …”
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Big data for imaging assessment in glaucoma
Published 2024-09-01“…Leveraging vast data sources, these technologies promise to enhance clinical practice and public health outcomes by enabling earlier disease detection, progression forecasting, and deeper understanding of underlying mechanisms. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development
Published 2025-08-01“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes
Published 2025-02-01“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
Published 2025-03-01“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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Mineral identification in thin sections using a lightweight and attention mechanism
Published 2025-04-01“…Mineral identification is foundational to geological survey research, mineral resource exploration, and mining engineering. Considering the diversity of mineral types and the challenge of achieving high recognition accuracy for similar features, this study introduces a mineral detection method based on YOLOv8-SBI. …”
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1195
Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs
Published 2025-05-01“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease.
Published 2024-01-01“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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1198
Bioactive matters based on natural product for cardiovascular diseases
Published 2024-12-01Get full text
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Energy filtering enables macromolecular MicroED data at sub-atomic resolution
Published 2025-03-01“…While direct electron detection essentially eliminates the read-out noise during MicroED data collection, other sources of noise remain and limit the measurement of faint high-resolution reflections. …”
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