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WHO malaria nucleic acid amplification test external quality assessment scheme: results of eleven distributions over 6 years
Published 2025-03-01“…The use of nucleic-acid amplification (NAAT) for detection of Plasmodium spp. has expanded rapidly in recent years, for epidemiological research globally and clinical care in high-resource settings. …”
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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
Published 2025-03-01“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs
Published 2025-05-01“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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1264
Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics
Published 2025-01-01“…Flavonoids related to medicinal effects, such as naringin and hesperidin, were significantly more abundant in Huazhou pomelo than in Sanhong pomelo, with compounds such as 5-demethylnobiletin detected only in Huazhou pomelo. The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Unraveling the microbiome–aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars
Published 2025-07-01Get full text
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1267
Species-level enumeration of low-concentration lactic acid bacteria in breast milk
Published 2025-12-01Get full text
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Rosaceae phylogenomic studies provide insights into the evolution of new genes
Published 2025-01-01“…Functional analysis exhibited that newly formed fusion genes can regulate the phenotype traits of plant growth and development, suggesting the functional significance of these genes. …”
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DUALZ—Deep UNCOVER-ALMA Legacy High-Z Survey
Published 2025-01-01“…We also detect a marginal dust emission from an X-ray-detected galaxy at z _spec = 10.07, suggesting an active coevolution of the central black hole and its host. …”
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1272
The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis
Published 2025-05-01“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
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Microfluidic Nanobioplatform-Based Immunosensor for Monitoring of 25-Hydroxy Vitamin-D3
Published 2024-01-01“…The use of proposed immunosensor to serum samples would allow early detection of 25-VitD _3 deficiency, particularly in rural and resource-constrained settings.…”
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De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii
Published 2025-01-01“…Validation by BUSCO confirmed the high quality of our resources. Homology alignments of predicted ORFs showed that 21,842 sequences from Ae. mariae and 21,944 sequences from Ae. zammitii mapped to the Nr, SwissProt, and TrEMBL databases, while 19,208 and 19,393 predicted ORFs, respectively, were functionally annotated using the COG and KEGG databases. …”
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Kolmogorov–Arnold Networks for Automated Diagnosis of Urinary Tract Infections
Published 2025-03-01“…By rapid UTI detection, the proposed methodology reduces diagnostic delays, minimizes human error, and streamlines laboratory workflows. …”
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Assessing the Influence of Selected Permeabilization Methods on Lymphocyte Single-Cell Multi-Omics
Published 2025-02-01“…(1) Background: Single-cell multi-omics is a powerful method for the dissection and detection of complicated immunologic functions and synapses. …”
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Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China
Published 2025-08-01“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
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Who Leads Trends on Q&A Platforms? Identifying and Analyzing Trend Discoverers
Published 2024-01-01“…The insights derived from this research have crucial implications for improving the development and functionality of Q&A platforms.…”
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