Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors by Jing Zhang, Wei Liu, Minghui Bao, Peng Yang, Xuhua Liu, Zhihong Fu

“…Then calculate the correlation function of the reconstructed signal echo and apply a smooth pseudo Wigner Ville distribution for time-frequency analysis. …”
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Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples by Chioma Lilian Ozoaduche, Balázs Libisch, Daniel Itoro, Iyore Blessing Idemudia, Katalin Posta, Ferenc Olasz

“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction by A. V. Pikuza, A. M. Zakirov

“…Special research methods included the assessment of the state of the microbicidal function of neutrophilic granulocytes using reactive spontaneous (SSLCL) and zymosan-induced luminol-dependent chemiluminescence tests (ILZHL). …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves&rsquo; Disease and Graves&rsquo; Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis by Reza Hashemi, Mohammad M. Hussein M. Raouf, Tanya S. Salih, Marzieh Feyzpour, Maryam Eskandarioun, Najmeh Nezamabadipour, Hossein Gandomkar

“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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Chemometrically assisted optimization and validation of the HPLC method for the analysis of alectinib and its related impurity with measurement uncertainty evaluation and whiteness... by Serkan Levent, Abeer Elriş, Hazal Avcı, Saniye Özcan, Nafiz Öncü Can

“…This made it possible to find and measure the sources of uncertainty as well as the factors that affected the chromatographic responses. …”
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Catalytic Effects of Different Metal Salts on Cotton Waste Textiles by Pyrolysis: Pyrolysis Behavior and Properties of Activated Carbon by Yixiao Zhang, Xingjie Zhao, Si Chen

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Genetic Factors for the Natural Elimination of Hepatitis C Virus by N. V. Vlasenko, T. A. Loscutova, K. O. Mironov, A. S. Esman, E. A. Dunaeva, T. A. Semenenko, D. B. Dubodelov, M. I. Korabelnikova, Z. B. Ponezheva, V. V. Makashova, K. G. Omarova, A. V. Sacuk, G. G. Solopova, S. N. Kuzin, V. G. Akimkin

“…Additionally, the significance of polymorphisms at the intragenic and intergenic levels was assessed using modern bioinformatic resources in the field of functional genomics.Results. …”
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Environmental DNA as a tool for soil health monitoring and unveiling new ecological frontiers by Yuan Zhang, Weijun Lu, Kaihang Xing, Fen Guo, Qingping Du, Xinfei Zhang, Fan Zhang, Zongyao Qian, Feilong Li

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An Observational Study on Pre-natal Diagnosis of Congenital Talipes Equinovarus by Gaurav Vatsa, Saurabh Suman, Siddharth Kumar Singh

“…Future research should assess long-term functional outcomes and optimize pre-natal screening protocols, particularly in resource-limited settings, to ensure comprehensive CTEV management.…”
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Unraveling the mitochondrial genome of the medicinal Chinese motherwort (Leonurus japonicus, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary i... by Xinyu Bai, Xinyu Bai, Tingting Zhu, Huiru Chen, Xiaoqun Wang, Jing Liu, Yuqing Feng, Yuqing Feng, Yanbo Huang, Joongku Lee, Goro Kokubugata, Zhechen Qi, Xiaoling Yan

“…Extensive RNA editing underscores post-transcriptional regulation in mitochondrial function. These findings enrich genomic resources for Leonurus, support phylogenetic and evolutionary studies in Lamiaceae, and lay groundwork for molecular breeding and conservation strategies targeting mitochondrial traits. …”
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Development and characterization of a new TILLING population of common bread wheat (Triticum aestivum L.). by Liang Chen, Linzhou Huang, Donghong Min, Andy Phillips, Shiqiang Wang, Pippa J Madgwick, Martin A J Parry, Yin-Gang Hu

“…The results indicate that this mutant population represents a useful resource for the wheat research community. We hope that the use of this reverse genetics resource will provide novel allelic diversity for wheat improvement and functional genomics.…”
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A Spatial–Frequency Combined Transformer for Cloud Removal of Optical Remote Sensing Images by Fulian Zhao, Chenlong Ding, Xin Li, Runliang Xia, Caifeng Wu, Xin Lyu

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Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…In comparison to the RNAi-mediated gene silencing of <i>dicer-2</i>, <i>argonaute-2b</i>, and <i>piwi5</i>, our Cas9/sgRNA approach showed an enhanced ability to detect antiviral effects. <b>Conclusions</b>: We propose that this cell line offers a new tool for studying gene function in <i>Cx. quinquefasciatus</i> mosquitoes that avoids the use of RNAi. …”
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mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms by Barnabé, Christian, Sempéré, Guilhem, Manzanilla, Vincent, Millan, Joel Moo, Amblard-Rambert, Antoine, Waleckx, Etienne

“…It provides functions for various tasks such as dereplication, clustering, chimera detection, and taxonomic assignment. …”
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Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria by Hadjira Guenane, Boulanouar Bakchiche, Ramazan Erenler, Ilyas Yildiz, Omar M. Khalaf, Amal M. Saad, Mosad A. Ghareeb

“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
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Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis by Zhengzheng Jiang, YaWen Shen

“…IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. …”
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Seismic fault identification method based on CBAM-TransUNet by Xin WANG, Wei ZHANG, Tongjun CHEN, Ao ZHANG, Dang ZHAO

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A data driven approach using local measurements to locate turbine governors causing forced oscillations by Sigurd Hofsmo Jakobsen, Xavier Bombois, Santiago Sanchez Acevedo, Hallvar Haugdal, Salvatore D’Arco

“…When forced oscillations are detected, they are located by finding the transfer functions that describe the behaviour of the corresponding plant the worst. …”
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