Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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rangr: An R package for mechanistic, spatially explicit simulation of species range dynamics by Katarzyna Markowska, Katarzyna Malinowska, Lechosław Kuczyński

“…Several mechanistic, spatially explicit models have been proposed to address this issue, but they do not cover the full range of potential functionalities. We present a new open‐source R package called rangr, which integrates population dynamics and dispersal into a mechanistic virtual species simulator. …”
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A novel method for accelerating surgical wound healing in rabbits by collagen extraction from carp (Cyprinus carpio) fish skin by Shahbaa Kh. Al-Taee

“…The extracted collagen was characterized by low viscosity, transparency, and a watery consistency; the functional groups of collagens were detected using Fourier Transform Infrared Spectroscopy. …”
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Host selection is not a universal driver of phyllosphere community assembly among ecologically similar native New Zealand plant species by Anya S. Noble, Jaber Abbaszadeh, Charles K. Lee

“…Abstract Background A growing body of evidence demonstrates that host-associated microbial communities of plant leaf surfaces (i.e. the phyllosphere) can influence host functional traits. However, it remains unclear whether host selection is a universal driver of phyllosphere community assembly. …”
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Unraveling the complexities: morpho-physiological and proteomic responses of pearl millet (Pennisetum glaucum) to dual drought and salt stress by Charlie Sithole, Rotondwa Rabelani Sinthumule, Joseph Lesibe Gaorongwe, Oziniel Ruzvidzo, Tshegofatso Bridget Dikobe

“…Catalytic and binding activities were the predominant molecular functions detected across treatments suggesting their central role in stress response. …”
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INDICATORS AND CRITERIA FOR ASSESSMENT OF MULTIFUNCTIONAL DEVELOPMENT OF RURAL TERRITORIES by O. V. Kosenchuk, A. V. Zinich

“…The authors identify five basic functions of rural areas, developed and presented by the author’s methodology for monitoring the dynamic and including thirty-one indicators, which allow to assess the changes in rural area over the years.Discussion. …”
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Inference of a plume conduit beneath the Réunion Island from 3D migration of Ps conversions from the mantle transition zone by B. Padma Rao, M. Ravi Kumar

“…In this study, we investigate the mantle transition zone (MTZ) structure beneath the Réunion Island using 3D-migration of P-Receiver functions, to decipher the effect of the plume on the MTZ and its architecture. …”
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Urotensin-II: More Than a Mediator for Kidney by Ayşe Balat, Mithat Büyükçelik

“…Although both hU-II and its receptor, GPR14, are detected in several tissues, kidney is a major source of U-II in humans. …”
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Utilization of Date palm (Phoenix dactylifera L.) wastes for bioethanol production using Pichia kudriavzevii strains by Folake T. Afolabi, Ibukun E. Ola

“…Moreover, the Pichia kudriavzevii strains could be recommended for bioethanol production at 30 % inoculum size, on using sucrose as a carbon source and yeast extract as a nitrogen source. On using the Fourier-Transform Infrared (FTI) spectroscopy, the detected functional group of the produced bioethanol was O-H group. …”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Work package 4: Development and refinement of a care transitions intervention Intervention development Functional resonance analysis method was used to model the transition process. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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Development and validation of liquid–liquid phase separation-associated prognostic biomarkers in gastric cancer by Donghui Liu, Mingzhu Liu, Juan Du

“…Abstract Objective Liquid–liquid phase separation (LLPS) is the membrane-less formation of functional assemblies from specific molecules. It plays a key role in tumor growth by governing gene expression. …”
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Regularities of the Natural Evolution of the Proliferative Process in Diabetic Retinopathy. The Concept of Remission of Proliferative Diabetic Retinopathy by S. V. Sdobnikova

“…Therefore, the scale reflecting the stages of evolution of newly formed vessels and the scale of severity reflecting the degree of threat to visual functions in PDR cannot be identical. Since the development and regression of neovessels is a reflection of multidirectional processes, the identification of the phase of PDR evolution is fundamental in the formation of research design. …”
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Investigation of some probiotic properties of Lactobacillaceae strains isolated from traditional Tulum cheese in Turkey by Eda Kiliç Kanak, Suzan Öztürk Yilmaz

“…Important information was obtained on the probiotic and functional properties of Lactobacillaceae strains isolated from traditionally fermented Tulum cheese, which can be used as a rich source of probiotic bacteria. …”
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Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer’s Disease Diagnosis by Maria João Oliveira, Pedro Ribeiro, Pedro Miguel Rodrigues

“…<i>MCI</i>, the proposed model outperformed state-of-the-art imaging source studies by 0.1% and non-imaging source studies by 4.6%. …”
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Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3 by Lisa Morand-Laffargue, Florence Charles, Charlotte Sabran, Patrick Borel

“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…An algorithm was designed to detect these cases based on the geometry of the street segments. …”
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Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria by Nirasha Atapattu, Nicolas Justus, Hariniha Selvarajan, Mitzchilouise Baylosis, Marc Schieven, Kalindi D. Morgan

“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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Regional and strain-level prevalence of nitrogen-fixing Bradyrhizobium with potential N2O reduction in South Korea by Jaeyoung Ro, Hor-Gil Hur, Sujin Lee

“…Abstract Agricultural practices are the largest anthropogenic source of nitrous oxide (N2O), a potent greenhouse gas contributing to global climate change. …”
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