Identification of miRnas with possible prognostic roles for HAM/TSP by Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Youko Nukui, Juliana Pereira, Rosa Nascimento Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

“…The seven most deregulated miRs target genes have been associated with a variety of biological processes and molecular functions. The reactome pathways relevant to our findings provide a rich source of data and offer the opportunity to better understand sRNA regulation and function in HTLV-1 pathophysiology. …”
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Epidemiology of Disability of Adult Population in the Russian Federation by S. N. Puzin, M. A. Shurgaya, N. V. Dmitrieva, G. E. Pogosyan, I. V. Lyalina, A. M. Mammaraeva, T. A. Ivanova, L. S. Idrisova

“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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There is no transfer of mitochondria from donor hematopoietic cells to recipient mesenchymal stromal cells after allogeneic hematopoietic stem cells transplantation in humans by Natalya Sats, Vadim Surin, Tatiana Abramova, Aleksandra Sadovskaya, Nataliya Petinati, Nikolay Kapranov, Ksenia Nikiforova, Nina Drize, Luisa Karaseva, Olga Pokrovskaya, Larisa Kuzmina, Elena Parovichnikova

“…Mitochondria, which can be transferred between cells via nanotubes or extracellular vesicles, play a key role in the functions of mesenchymal stromal cells. In a murine model, donor hematopoietic stem and progenitor cells transfer functional mitochondria to bone marrow mesenchymal stromal cells of the recipient. …”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

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Joint Survey Processing. III. Compact Oddballs in the COSMOS Field—Little Red Dots and Transients by Yu-Heng Lin, Andreas L. Faisst, Ranga-Ram Chary, Anton M. Koekemoer, Joseph Masiero, Daniel Masters, Vihang Mehta, Harry I. Teplitz, Gregory L. Walth, John R. Weaver

“…We draw the upper limit of the AGN luminosity function Φ = 1.1 × 10 ^−7 Mpc ^3 mag ^−1 for M _UV = −21 at redshift of 6. …”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. …”
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Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response by Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe

“…Across bvFTD and PSP groups, the beta response to deviant stimuli (relative to standard stimuli) correlated with clinical severity, but not with atrophy of the prefrontal source region. These findings confirm the proposed importance of higher-order cortical regions, and their beta-power generators, in sensory change detection and context-updating during oddball paradigms. …”
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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

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The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021 by Jian Zhou, Long Gu, Fengling Du, Chun Li, Fan Zhang, Xianhui Zhang, Jinwei Pang, Bingqing Xie, Xiangyu Wang, Jianhua Peng, Yong Jiang

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Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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High-resolution genetic and physical mapping reveals a peanut spotted wilt disease resistance locus, PSWDR-1, to Tomato spotted wilt virus (TSWV), within a recombination cold-spot... by Dongliang Wu, Chuanzhi Zhao, Walid Korani, Ethan A. Thompson, Hui Wang, Gaurav Agarwal, Jake C. Fountain, Albert Culbreath, C. Corley Holbrook, Xingjun Wang, Josh P. Clevenger, Baozhu Guo

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Biomechanical Changes to the Ankle After Zadek Osteotomy by Nicholas Bellas MD, Raghunandan Nayak BS, Mehreen Pasha BS, Megan R. Wolf MD, Elifho Obopilwe MS, Thomas McDonald MD, Lauren E. Geaney MD

“…Category: Hindfoot; Sports Introduction/Purpose: Insertional Achilles tendinopathy is a common source of heel pain in active adults and athletes. …”
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Potential physiological mechanisms behind variation in rainbow trout (Oncorhynchus mykiss) to biosynthesize EPA and DHA when reared on plant oil replacement feeds by Ken Overturf, Jason Abernathy, Dietmar Kültz, Jacob Bledsoe, Shawn Narum, Thomas Welker

“…The omega-3 fatty acids, docosahexaenoic acid (DHA; 22:6n-3) and eicosapentaenoic acid (EPA; 20:5n-3), are of primary concern as they provide significant health benefits such as reducing inflammation and improving heart and health function. However, the DHA; 22:6n-3 and EPA; 20:5n-3 available for aquaculture feeds is primarily provided by fish oil which is already limited in availability and expensive, and dietary lipids are consistently being replaced with oil sourced from plants. …”
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Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach by Zhengyuan Su, Huadong Jiang, Ying Yang, Xiangqing Hou, Yanli Su, Li Yang

“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
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Estimating the mass of tephra accumulated on roads to best manage the impact of volcanic eruptions: the example of Mt Etna, Italy by L. Mereu, L. Mereu, M. Stocchi, M. Stocchi, A. Garcia, M. Prestifilippo, L. Sandri, C. Bonadonna, S. Scollo

“…First, we analysed a sequence of 39 short-lasting and intense lava fountains detected by the X-band weather radar, applying a volcanic ash radar retrieval approach that permits us to compute the main eruption source parameters (ESPs), such MER, <span class="inline-formula"><i>H</i>_TP</span>, and GSD. …”
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Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress by Lauren A. Hennessy, Bhedita J. Seewoo, Liz A. Jaeschke, Leah A. Mackie, Abbey Figliomeni, Yasmin Arena-Foster, Sarah J. Etherington, Sarah A. Dunlop, Paul E. Croarkin, Jennifer Rodger

“…Behaviour was assessed using the Elevated Plus Maze and Forced Swim Test, and functional, chemical, and structural brain changes measured using magnetic resonance imaging techniques. …”
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OGLE-2011-BLG-0462: An Isolated Stellar-mass Black Hole Confirmed Using New HST Astrometry and Updated Photometry by Kailash C. Sahu, Jay Anderson, Stefano Casertano, Howard E. Bond, Martin Dominik, Annalisa Calamida, Andrea Bellini, Thomas M. Brown, Henry C. Ferguson, Marina Rejkuba

“…We have reanalyzed the data, including the new HST astrometry, and photometry obtained with 16 different telescopes. The source lies only $0\mathop{.}\limits^{^{\prime\prime} }4$ from a bright neighbor, making it crucial to perform precise subtraction of its point-spread function (PSF) in the astrometric measurements of the source. …”
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