circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p by Jiayuan Su, Jinrong Zhou, Yachan Feng, Haojie Zhang, Xinyu Zhang, Xiaorong Zhao, Yong Li, Xueling Guo

“…Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers, accounting for around 80% of total lung cancer cases worldwide. Exploring the function and mechanism of circRNAs could provide insights into the diagnosis and treatment for NSCLC. …”
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An Observational Study on Pre-natal Diagnosis of Congenital Talipes Equinovarus by Gaurav Vatsa, Saurabh Suman, Siddharth Kumar Singh

“…Future research should assess long-term functional outcomes and optimize pre-natal screening protocols, particularly in resource-limited settings, to ensure comprehensive CTEV management.…”
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A New [PMo₁₂O₄₀]³⁻-Based Ni^II Compound: Electrochemical and Photocatalytic Properties for Water Pollutant Removal by Guoqing Lin, Shufeng Liu, Dai Shi, Ying Yang, Fangle Yu, Tong Lu, Xiao-Yang Yu, Yuguang Zhao

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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

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mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms by Barnabé, Christian, Sempéré, Guilhem, Manzanilla, Vincent, Millan, Joel Moo, Amblard-Rambert, Antoine, Waleckx, Etienne

“…It provides functions for various tasks such as dereplication, clustering, chimera detection, and taxonomic assignment. …”
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Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria by Hadjira Guenane, Boulanouar Bakchiche, Ramazan Erenler, Ilyas Yildiz, Omar M. Khalaf, Amal M. Saad, Mosad A. Ghareeb

“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
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Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis by Zhengzheng Jiang, YaWen Shen

“…IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. …”
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Genome-wide landscape of genetic diversity, runs of homozygosity, and runs of heterozygosity in five Alpine and Mediterranean goat breeds by Sara Pegolo, Vittoria Bisutti, Lucio Flavio Macedo Mota, Alessio Cecchinato, Nicolò Amalfitano, Maria Luisa Dettori, Michele Pazzola, Giuseppe Massimo Vacca, Giovanni Bittante

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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin by Liping Wang, Shufang Wang, Jing Li, Xingnan Zhang

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A data driven approach using local measurements to locate turbine governors causing forced oscillations by Sigurd Hofsmo Jakobsen, Xavier Bombois, Santiago Sanchez Acevedo, Hallvar Haugdal, Salvatore D’Arco

“…When forced oscillations are detected, they are located by finding the transfer functions that describe the behaviour of the corresponding plant the worst. …”
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HpFBH3 transactivates HpCO7 via binding to the E-boxes in the promoter and may accelerate flower formation in pitaya by Xiaowei Cai, Ling Xiao, Xiangmei Nie, Qiandong Hou, Sulin Wen, Kun Yang, Xiaopeng Wen

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Non-Targeted Lipidomics Analysis of Characteristic Milk Using High-Resolution Mass Spectrometry (UHPLC-HRMS) by Tingting Wei, Tianxiao Zhou, Shenping Zhang, Zhexue Quan, Yang Liu

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Multimessenger Signatures of a Deformed Magnetar in Gamma-Ray Bursts by Parisa Hashemi, Soroush Shakeri, Yu Wang, Liang Li, Rahim Moradi

“…It is shown that the GW and EM emissions evolve as a function of eccentricity and rotational frequency with time. …”
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Identification of miRnas with possible prognostic roles for HAM/TSP by Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Youko Nukui, Juliana Pereira, Rosa Nascimento Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

“…The seven most deregulated miRs target genes have been associated with a variety of biological processes and molecular functions. The reactome pathways relevant to our findings provide a rich source of data and offer the opportunity to better understand sRNA regulation and function in HTLV-1 pathophysiology. …”
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Renal Biopsy Pathological Tissue Segmentation: A Comprehensive Review and Experimental Analysis by Yan Liu, Taiping Wang, Xinxin He, Wei Wang, Qiang He, Juan Jin

“…This study provides a novel technical framework for precise renal pathological tissue segmentation and lays the foundation for future lesion detection and intelligent diagnostic applications.…”
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The influence of genetics on the endocannabinoid system gene expression and relevance for targeting reproductive conditions by Keisuke Tanaka, Akwasi A. Amoako, Sally Mortlock, Peter A. W. Rogers, Sarah J. Holdsworth-Carson, Jacqueline F. Donoghue, Wan Tinn Teh, Grant W. Montgomery, Brett McKinnon

“…Abstract Background Endocannabinoids are small lipid molecules that have critical roles in cellular proliferation and function. They are produced locally with their concentrations controlled via the endocannabinoid system (ECS). …”
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Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
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LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION by V. Sarancha, K. Vitale, S. Oreskovic, V. Sulyma

“…Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.…”
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Quality and content evaluation of thyroid eye disease treatment information on TikTok and Bilibili by Haisheng Wang, Huahong Zhang, Jiamin Cao, Feng Zhang, Wei Xiong

“…Abstract Thyroid eye disease (TED) is an autoimmune condition that commonly impacts patients’ visual function, appearance, and psychological well-being. …”
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Investigation and Application of Water-Saving Monitoring Technology in Public Institutions by WANG Kang, ZHENG Yongjie, ZHANG Zhen, TANG Yanping, SONG Wenhao, GUO Xiaoming

“…Considering the characteristics of water use and the current situation of water facilities in public institutions,this study comprehensively employs the Internet of Things (IoT),cloud deployment,databases,three-dimensional (3D) visualization,and other advanced techniques to create a water-saving reconstruction scheme with integrated software and hardware for public institutions.Therefore,a smart water management platform for public institutions is built to implement advanced water-saving concepts and improve the water management level.The main research results are as follows:① By intelligent remote monitoring equipment,the multiclass water measurement network is designed to realize the fine collection of zonal water use data;② this study designs a reconstruction scheme of water facilities and explores the utilization mode of unconventional water sources to improve the utilization efficiency of water resources;③ multiple algorithms and statistical methods are used to analyze the time series of water use data,and thus this study realizes the analysis of pipeline network leakage and damage,identification of water use anomalies,and water-saving statistical analysis,and the investigation of water use laws;④ the platform with functions of monitoring and early warning is established to achieve real-time remote monitoring of water use,statistical analysis of historical water use,and identification and warning of pipe network leakage,so as to detect water anomalies in time and save water.The research results are first applied to the construction of the water-saving institution of the Pearl River Water Resources Commission to build a benchmark for the construction of water-saving institutions in the southern region.On the basis of application experience,the comprehensively integrated monitoring technology for water-saving in public institutions is developed,which provides a new idea for public institutions to save water.…”
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