Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease. by Masayuki Fukumoto, Daisuke Miyamoto, Akihiko Soyama, Takanobu Hara, Yasuhiro Maruya, Peilin Li, Hajime Matsushima, Kazushige Migita, Takahiro Enjoji, Hanako Tetsuo, Takuro Fujita, Mampei Yamashita, Hajime Imamura, Tomohiko Adachi, Kengo Kanetaka, Takahiro Ochiya, Susumu Eguchi

“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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Bioactive matters based on natural product for cardiovascular diseases by Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou

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Energy filtering enables macromolecular MicroED data at sub-atomic resolution by Max T. B. Clabbers, Johan Hattne, Michael W. Martynowycz, Tamir Gonen

“…While direct electron detection essentially eliminates the read-out noise during MicroED data collection, other sources of noise remain and limit the measurement of faint high-resolution reflections. …”
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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

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Optimizing maize germination forecasts with random forest and data fusion techniques by Lili Wu, Yuqing Xing, Kaiwen Yang, Wenqiang Li, Guangyue Ren, Debang Zhang, Huiping Fan

“…Traditional methods for detecting seed germination rates often involve lengthy experiments that result in damaged seeds. …”
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Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours by Tobias Åkerström, Branislav Klimàcek, Matilda Annebäck, Olov Norlén, Peter Stålberg

“…Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. …”
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Antioxidant Profiling of Botryocladia leptopoda Based on In Silico and In Vitro Studies by Fenny Crista Anastasia Panjaitan, Huey-Jine Chai

“…Thus, B. leptopoda can be considered a promising source of antioxidative products in the functional food and pharmaceutical industries.…”
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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…The main literature searches were then conducted using six databases: Applied Social Sciences Index and Abstracts (ProQuest), Cumulative Index to Nursing and Allied Health Literature (EBSCO), MEDLINE (Ovid), PsycInfo (Ovid), EMBASE (Ovid) and Web of Science Core Collection (Emerging Sources Citation Index). The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. …”
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Chronic Stress protection for postnatal dEpREssioN prEvention (SERENE): a protocol for an exploratory study by Frederic Dutheil, Dahlia Tharwat, Marion Trousselard, Mélanie Balès, Anne-Laure Sutter-Dallay, Dominique Fromage, Elisabeth Spitz, Dominique Dallay, Thierry Harvey, Eric Welter, Frédéric Coatleven, Lydie Cherier, Frédérique Teissèdre, Jean-Luc Pouly, Anaïs M Duffaud

“…This psychological resource is linked to protective and resilient psychic functioning. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Advanced Microgrid Protection Utilizing Zero Sequence Components With Hard-Ware-in-the-Loop Testing by Zahra Ghanem, Feras Alasali, Naser El-Naily, Hassen Loukil, Haytham Y. Mustafa, Saad M. Saad, Abdelaziz Salah Saidi, William Holderbaum

“…Secondly, the study demonstrates the use of Configurable Function Blocks (CFCs) in digital relays to dynamically adjust relay settings based on zero sequence current detection. …”
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Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. …”
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Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response by Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe

“…Across bvFTD and PSP groups, the beta response to deviant stimuli (relative to standard stimuli) correlated with clinical severity, but not with atrophy of the prefrontal source region. These findings confirm the proposed importance of higher-order cortical regions, and their beta-power generators, in sensory change detection and context-updating during oddball paradigms. …”
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Species-level enumeration of low-concentration lactic acid bacteria in breast milk by Yue Sun, Qiming Li, Mengling Hu, You Wu, Yunchao Wa, Hai Lu, Shilong Jiang, Hui Wang, Qiaosi Wei, Yujun Huang, Ruixia Gu, Chenchen Zhang

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Microbial community characteristics and environmental response of water bodies in different environmental areas underground coal mine by Haitao ZHANG, Guangquan XU, Xiaoqing CHEN, Xu LI, Zixuan LI, Yanxi ZHANG, Gang ZHANG, Jianghui HE

“…These functions maintained the ecological balance of underground water bodies in coal mines and played an important role in regulating and restoring ecosystems.…”
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Influence of Organic Nitrogen Derived from Recycled Wine Lees and Inorganic Nitrogen on the Chemical Composition of Cabernet Sauvignon Wines Fermented in the Presence of Non-Saccha... by Claudia López-Lira, Pedro Valencia, Alejandra Urtubia, Esteban Landaeta, Ricardo A. Tapia, Wendy Franco

“…In this study, the influences of inorganic nitrogen source (INS) and organic nitrogen source (ONS) supplementation during the wine fermentation process using three non-Saccharomyces yeasts (<i>Candida zemplinina</i>, <i>Candida oleophila</i>, and <i>Candida boidinii</i>) were analyzed. …”
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