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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…A specific immunopeptidomics approach was developed to detect epitopes on human leukocyte antigens (HLA) molecules. …”
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1762
Oxidative Stress Markers and C-Reactive Protein Are Related to Severity of Heart Failure in Patients with Dilated Cardiomyopathy
Published 2014-01-01“…Increased MnSOD activity indicates the mitochondrial source of ROS in patients with advanced heart failure.…”
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1763
Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples
Published 2025-03-01“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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1764
Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (<i>Hippophae rhamnoides</i> L.) Pomace: Chemical Composition and Biological Activities
Published 2025-05-01“…Sea buckthorn pomace (SBP) is a rich source of flavonoid compounds with potential healthy properties. …”
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1765
Enhancing Medium-Chain Fatty Acid Delivery Through Bigel Technology
Published 2024-11-01“…This study presents the development and characterization of medium-chain fatty acid (MCFA)-loaded bigels, using coconut oil as the MCFA source. The bigels exhibited high oil binding capacity, ranging from 87% to 98%, effectively retaining MCFAs within the matrix, with lauric acid (C12) being the main component detected within the bigels at 178.32 ± 0.10 mg/g. …”
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1766
In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu...
Published 2025-06-01“…The changes in bacterial communities upon fermentation at family, genera and species level were detected via 16S rRNA Next Generation Sequencing and Quantitative real-time PCR. …”
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1767
Worlds Next Door: A Candidate Giant Planet Imaged in the Habitable Zone of α Centauri A. II. Binary Star Modeling, Planet and Exozodi Search, and Sensitivity Analysis
Published 2025-01-01“…Additionally, postprocessing with the principal-component-analysis-based Karhunen–Loéve image processing algorithm reveals a point source, called S 1, in 2024 August, detected at signal-to-noise ratio of 4–6 (3.3–4.3 σ ), a projected separation of ≈1 $\mathop{.}…”
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1768
Synthesis of aluminum oxide nanoparticles using seeds of Carica papaya and evaluation of it for antimicrobial, antioxidant, and photocatalysis activity
Published 2024-11-01“…The presence of an absorption peak at a wavelength of 272 nm in the synthesized nanoparticles was detected by UV–Vis spectroscopy analysis. The results of the FTIR study confirmed the existence of various chemicals and functional groups in the 500–4000 cm−1 range. …”
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1769
A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study
Published 2025-02-01“…When errors are detected, the tool processes the SNOMED CT Concept Model in JSON format and applies predefined error categories. …”
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1770
Identification and outcomes of acute kidney disease in patients presenting in Bolivia, Brazil, South Africa, and Nepal.
Published 2024-11-01“…High rates of persistent kidney disease and mortality after discharge highlight the importance of AKD follow-up in low-resource settings.…”
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1771
Model-Based Electroencephalogram Instantaneous Frequency Tracking: Application in Automated Sleep–Wake Stage Classification
Published 2024-12-01“…A critical component of sleep analysis is detecting transitions between wakefulness and sleep states. …”
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1772
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Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin
Published 2025-12-01“…Perforin and Granzyme B secretion by CD8+ T cells, as well as tumor cell apoptosis, were detected after co-culturing CD8+ T cells with READ tumor cells and ST8Sia1-overexpression (ST8Sia1-OE) tumor cells. …”
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1774
The Effect of Hearing Aid Amplification on Gait Parameters: A Pilot Study Using Ear-Worn Motion Sensors
Published 2025-04-01“…Additionally, we showed the potential of ear-worn sensors for detecting relevant gait changes. To achieve this, we used a hearing-aid-integrated accelerometer and our open-source EarGait framework comprising gait-related algorithms specifically developed for ear-worn sensors. …”
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1775
Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction
Published 2023-07-01“…The focus of purulent inflammation in the abdominal cavity serves as a source of concentration of antimicrobial mechanisms, among which the central role is played by neutrophilic granulocytes and factors cooperating with them. …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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1777
Compact and Handheld SiPM-Based Gamma Camera for Radio-Guided Surgery and Medical Imaging
Published 2025-06-01“…We characterized the intrinsic position resolution (tested with pulsed light) as being ~200 µm, and the sensitivity and resolution when detecting gamma rays from Tc-99m source measured between 134 and 481 cps/MBq and as good as 1.4–1.9 mm, respectively.…”
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1778
Identification of Soybean E1-E4 Gene Orthologs in the Guar Genome Using Comprehensive Transcriptome Assembly and Annotation
Published 2025-06-01“…Taub.), a well-known source of guar gum (food additive E 412). At high latitudes, e.g., in Russia, the main challenge for guar cultivation is the long photoperiod during summer, which delays flowering and maturation of guar plants. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis
Published 2025-08-01“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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1780
Vitamin C, Sugar Content, Color Intensity and Some Physicochemical Properties of Watermelon and Orange Peels
Published 2025-03-01“…Therefore, orange peel can be used as a natural antioxidant and color source in the food, pharmaceutical, and cosmetic industries.…”
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