Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation by Lianling Xu, Lianling Xu, Kaixuan Zeng, Kaixuan Zeng, Zuoyue Duan, Zuoyue Duan, Jing Liu, Yan Zeng, Miao Zhang, You Yang, Qulian Guo, Yanling Jin, Wenjun Liu, Ling Guo

“…BackgroundActive dietary flavonoids are a promising resource for novel drug discovery. Sweet potato, a widely cultivated functional crop, is abundant in flavonoids. …”
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Towards safe and sustainable by design nanomaterials: Risk and sustainability assessment on two nanomaterial case studies at early stages of development by Konstantina-Roxani Chatzipanagiotou, Foteini Petrakli, Joséphine Steck, Cécile Philippot, Sébastien Artous, Elias P. Koumoulos

“…Overall, this work aims to demonstrate the applicability of selected tools towards SSbD for NNMs, to bring NNM SSbD closer to practical implementation, and to support end-users.…”
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Clinical Surveillance vs. Anticoagulation For low-risk patiEnts with isolated SubSegmental Pulmonary Embolism: protocol for a multicentre randomised placebo-controlled non-inferior... by Marc Carrier, Christine Baumgartner, Drahomir Aujesky, Menno V Huisman, Frederikus A Klok, Jeanne Moor, Marc Righini, Jürg-Hans Beer, Martina Peluso, Damiana Rakovic

“…The ancillary outcomes are health-related quality of life, functional status and medical resource utilisation.Ethics and dissemination The local ethics committees in Switzerland have approved this protocol. …”
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Reviews and syntheses: Current perspectives on biosphere research 2024–2025 – eight findings from ecology, sociology, and economics by F. J. Bohn, F. J. Bohn, A. Bastos, R. Martin, A. Rammig, N. S. Koh, G. B. Sioen, G. B. Sioen, B. Buscher, L. Carver, F. DeClerck, M. Drupp, M. Drupp, R. Fletcher, M. Forrest, A. Gasparatos, A. Godoy-Faúndez, G. Hagedorn, M. C. Hänsel, J. Hetzer, T. Hickler, T. Hickler, C. B. Krug, S. Koot, S. Koot, X. Li, A. Luers, S. Matevich, H. D. Matthews, I. C. Meier, M. Migliavacca, A. Mohamed, S. O, D. Obura, B. Orlove, R. Orth, L. Pereira, M. Reichstein, L. Thakholi, P. H. Verburg, Y. Yoshida

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Bronchial asthma in children of Ukraine: medical and environmental parallels of morbidity and prevalence by O. P. Volosovets, Y. K. Bolbot, S. P. Kryvopustov, O. V. Mozyrska, M. V. Kryvopustova, M. P. Prokhorova, A. V. Kupkina

“…Over the past 25 years in Ukraine there has been 69.3% increase in prevalence and 22.9% increase in incidence of bronchial asthma among children. Predominance of detecting this pathology was in the group of children from large industrial and agro-industrial regions of the country with significant volumes of atmospheric pollutants from stationary sources of pollution.…”
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Molecular organization of the nanoscale surface structures of the dragonfly Hemianax papuensis wing epicuticle. by Elena P Ivanova, Song Ha Nguyen, Hayden K Webb, Jafar Hasan, Vi Khanh Truong, Robert N Lamb, Xiaofei Duan, Mark J Tobin, Peter J Mahon, Russell J Crawford

“…The molecular organization of the epicuticle (the outermost layer) of insect wings is vital in the formation of the nanoscale surface patterns that are responsible for bestowing remarkable functional properties. Using a combination of spectroscopic and chromatographic techniques, including Synchrotron-sourced Fourier-transform infrared microspectroscopy (FTIR), x-ray photoelectron spectroscopy (XPS) depth profiling and gas chromatography-mass spectrometry (GCMS), we have identified the chemical components that constitute the nanoscale structures on the surface of the wings of the dragonfly, Hemianax papuensis. …”
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Presepsin as a sepsis biomarker by K. A. Trunova

“…Presepsin was highly  sensitive in detecting late neonatal sepsis, burn sepsis, and also reflected the efficacy of therapy  in septic premature babies and severely burned patients. …”
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Innovations and Challenges in Intermediate Respiratory Care Units: Toward Effective Integration into the Hospital System by Beatriz Jara Chinarro, Laura Pazos Rodriguez, Miguel Cuchí Alfaro, Ainhoa Izquierdo Pérez, Silvia Aguado Ibañez, María Churruca Arrospide, Marta Soler Vigil, Cristina Moral, Carlos Almonacid

“…Original articles were selected for analysis. Additionally, recommendation documents on IRCUs from SEPAR and other Scientific Societies were reviewed. …”
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The Diversity of Cold Worlds: A Blended-light Binary Straddling the T/Y Transition in Brown Dwarfs by Daniella C. Bardalez Gagliuffi, Jacqueline K. Faherty, Genaro Suárez, Sherelyn Alejandro Merchan, Brianna Lacy, Ben Burningham, Klara Matuszewska, Rocio Kiman, Johanna M. Vos, Austin Rothermich, Jonathan Gagné, Caroline Morley, Melanie J. Rowland, Dan Caselden, Aaron Meisner, Adam C. Schneider, Marc J. Kuchner, Charles A. Beichman, Peter R. Eisenhardt, Christopher R. Gelino, Ehsan Gharib-Nezhad, Eileen C. Gonzales, Federico Marocco, Niall Whiteford, J. Davy Kirkpatrick

“…Carbon disequilibrium chemistry strongly shapes the mid-infrared spectra of these sources, as a complex function of the metallicity and surface gravity. …”
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Experimental Evaluation and Thermodynamic Analysis of Magnetic Fe₃O₄@La-Zr-MOFs for Highly Efficient Fluoride and Phosphate Removal by Ziyi Zhang, Xinyun Chen, Yongyi Yu, Wenbin Pan, Ruilai Liu, Jiangyan Song, Jiapeng Hu

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THBS1 is a new autosomal recessive non-syndromic hearing impairment gene by Thashi Bharadwaj, Anushree Acharya, Fati Ullah Khan, Saadullah Khan, Irfan Ullah, Isabelle Schrauwen, Wasim Ahmad, Suzanne M. Leal

“…Using Sanger sequencing select variants were validated and tested for segregation using DNA samples from additional family members. …”
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Lassa fever survivors: long-term health effects and chronic sequelae – a scoping review by Sulymon A. Saka, Qudus O. Lawal, Osahon Otaigbe, Faustina F. Blackie, Osazuwa Ighodaro, Perpetua I. Odafen, Sylvanus Okogbenin

“…Methods A systematic literature search was conducted in PubMed/MEDLINE, Embase, and Google Scholar (up to September 2024) for English-language studies reporting physical, psychological, and functional outcomes ≥ 4 weeks post-recovery. Studies were selected using PCC framework (Population: Lassa survivors; Concept: Long-term sequelae; Context: Endemic regions globally). …”
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Sustainable water treatment using thermally stable natural clay: dual adsorption–thermolysis approach for organic pollutants and nitrate removal by Iyad Dawood, Ahed H. Zyoud, Shaher Zyoud, Ameed Amireh, Samer H. Zyoud, Tae Woo Kim

“…The results position thermally regenerated natural clay as a promising candidate for large-scale applications in water purification, particularly in resource-limited settings.…”
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Use of Remote Assessment Tools to Substitute Routine Outpatient Care: Scoping Review by Jayne Barclay, Clair Sullivan, Michael Beckmann, Graeme Mattison, Rebecca Runciman, Elizabeth Martin

“…A detailed search strategy was used across multiple databases, with studies selected based on predefined inclusion and exclusion criteria. …”
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Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics by Haiting Huang, Yu Liu, Jianmu Su, Xiangxiu Liang, Hong Wu, Mei Bai

“…Flavonoids related to medicinal effects, such as naringin and hesperidin, were significantly more abundant in Huazhou pomelo than in Sanhong pomelo, with compounds such as 5-demethylnobiletin detected only in Huazhou pomelo. The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Who Leads Trends on Q&A Platforms? Identifying and Analyzing Trend Discoverers by Yongning Li, Lun Zhang, Ye Wu, Tianlan Wei

“…Q&A platforms are vital sources of information but often face challenges related to their high ratios of passive to active contributors, which can impede knowledge construction and information exchange on the platforms. …”
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Civil Servants and Political Leaders’ Performance in Service Delivery in Kisoro District Local Government, Uganda. by Zigira Sam, Niyonzima

“…It targeted civil servants and political leaders of Kisoro District and used a sample of 80 respondents who were selected using simple random and purposive sampling techniques. …”
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Unlocking the potential of circulating small extracellular vesicles in neurodegenerative disease through targeted biomarkers and advancements in biosensing by Saqer Al Abdullah, Ivy Cocklereece, Kristen Dellinger

“…Neurodegenerative diseases (NDDs) gradually affect neurons impacting both their function and structure, and they afflict millions worldwide. …”
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New Thermoelectric Sensor Adapted to Realize an Infrared Radiations Detector by Mohammed Rahmoun, Khalid Hachami, Abdelwahad Touil, Benaissa Bellach, Mohammed Bailich, Ammar Merdani

“…The present paper deals with the design and the realization of a new thermoelectric sensor (Seebeck), sensitive to the infrared radiations emitted by different sources. The function mechanism utilizes radiative absorption phenomena, heat transfer, and thermoelectric effects. …”
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Dental and oral health assessments in the German National Cohort (NAKO) by Stefanie Samietz, Katrin Borof, Katrin Hertrampf, Ghazal Aarabi, Antonio Ciardo, Hannah Finke, Daniel Hagenfeld, Jan Kühnisch, Maurice Rütters, Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Ti-Sun Kim, Thomas Kocher, Wolfgang Ahrens, Hermann Brenner, Carina Emmel, Beate Fischer, Amand Führer, Karin Halina Greiser, Jasmin Grischke, Kathrin Günther, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Yvonne Kemmling, Alexander Kluttig, Lilian Krist, Oliver Kuss, Michael Leitzmann, Claudia Meinke-Franze, Karin B. Michels, Nadia Obi, Anette Peters, Nicole Pischon, Tobias Pischon, Sabine Schipf, Börge Schmidt, Henning Teismann, Stefan Rupf, Birte Holtfreter

“…As part of the Level 2 program that was offered to 20% randomly selected participants, each study centre selected one of three modules, one of them being the Level 2 oral examination. …”
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