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1461
Quand l’écriture entre dans le quotidien : les mots de la mémoire dans les livres de raison (Provence, fin xve-xviiie siècles)
Published 2025-05-01“…This lexicon is correlated with the functions of memory aids and records (these books of reason could be used as evidence in court), which allows us to question the way words and signs functioned in memory techniques (repetitions, reformulations, mnemonic use of genealogies, reference to historical events, etc.) developed by scribblers often unfamiliar with the learned “arts of memory”. …”
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1462
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1464
Factors influencing brain recovery from stroke via possible epigenetic changes
Published 2024-12-01“…Aim: To examine epigenetic changes leading to functional repair after damage to the central motor system.Data sources: A literature search was conducted using medical and health science electronic databases (PubMed, MEDLINE, Scopus) up to July 2023.Study selection: Data were summarized for type of intervention, study design, findings including human and animal studies.Data extraction: Data were extracted and double-checked independently for methodological quality. …”
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1465
Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema
Published 2023-02-01“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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1466
Adverse effects of immunosuppressive therapy after kidney transplant
Published 2025-03-01“…This paper reviews the sources and generality of knowledge regarding the adverse effects of immunosuppressive therapy, which play an important role in the full functioning of a transplant. …”
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1467
Identification and characterization of the powdery mildew resistance in cultivated emmer wheat accession Lxd-682 via bulked segregant RNA sequencing
Published 2025-05-01“…Molecular markers JS717/JS718 and WGRC1096 were confirmed to be available for marker-assisted selection (MAS) of PmLxd-682 in breeding practices. …”
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1468
Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area
Published 2025-03-01“…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
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1469
Extraction, Isolation, and TEMPO-NaBr-NaClO Oxidation Modification of Cellulose from Coffee Grounds
Published 2025-04-01“…These chemical modifications improve the cellulose’s reactivity, broadening its potential applications in various fields, including biocomposites, sustainable packaging materials, and functional films. This work demonstrates the feasibility of utilizing coffee ground residues as a renewable, eco-friendly source of modified cellulose for high-value applications.…”
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Microfluidic Nanobioplatform-Based Immunosensor for Monitoring of 25-Hydroxy Vitamin-D3
Published 2024-01-01“…The use of proposed immunosensor to serum samples would allow early detection of 25-VitD _3 deficiency, particularly in rural and resource-constrained settings.…”
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1471
Explaining the Comprehensive Human-To-Human Marketig System in the Health Tourism Industry
Published 2025-03-01“…The system integrates 24 main categories, each associated with specific functions, ensuring a holistic approach to marketing that aligns with human-centric principles and Iran’s cultural and institutional context. …”
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Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress
Published 2022-09-01“…Behaviour was assessed using the Elevated Plus Maze and Forced Swim Test, and functional, chemical, and structural brain changes measured using magnetic resonance imaging techniques. …”
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Characteristics, Distribution, and Source Analysis of the Main Persistent Toxic Substances in Karst Groundwater at Jinan in North China
Published 2020-01-01“…Based on the abundant karst water samples, the concentration, detection, and spatial distribution of toxic heavy metals and typical organic substances in karst waters were analyzed, the quality was evaluated, and the source of substances was analyzed. …”
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The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis
Published 2025-05-01“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
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1475
Research Status and Development Trend of Deep-sea Work Class ROV in China
Published 2020-01-01“…Deep-sea work class ROV plays an important role in marine exploration, resource development and marine environment protection. …”
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1476
The synthesis of the Gospel and life as a goal of evangelization
Published 2024-06-01“…In implementing the priestly function, the focus was on celebrating the Eucharist, revealing it as a source of human strength and energy, a school of sacramental perception of life and appreciation of matter, as well as a space for forming a new man. …”
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Risk Analysis of Groundwater Contaminant in Rural Areas Using Spatial Distribution
Published 2024-11-01“…Background: Water is a very important material for the life of creatures in nature and its function for life cannot be replaced by other compounds. …”
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1478
Understanding Silent Eruptions of Depression among Youngsters and Adolescents
Published 2024-11-01“…Research on the general population is the only source of information on many significant issues regarding depression in young people. …”
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1479
Preparation Process Optimization and Physicochemical Properties Characterization of Jinhua Ham Enzymolysis Peptide
Published 2025-07-01“…To investigate the potential of enzymatic hydrolysis for enhancing the nutritional and functional properties of Jinhua ham, a concentrated extract produced by dialysis desalination was employed as a substrate. …”
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1480