Current status of transcriptome sequencing technology in ruminants by Cui JiaYu, Song Lili, Wang Dawei, Liu ZhiLin, Zhang Xin, Jia Zelin, Zhang Yuhang, Xiong Huisheng, Wang Xueli

“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis by Huasong Zhang, Cong Fan, Ling Li, Feiyi Liu, Shaoying Li, Linyun Ma, Yuanhao Yang, David N. Cooper, Yuedong Yang, Ronggui Hu, Huiying Zhao

“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
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Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains by Yuanyuan Li, Xi Xiang, Zhiyuan Ren, Rui Wang, Minghui Xie, Gen Li, Xiaohui Yan, Zhilong Zhao, Zixin Deng, Min Xu, Anwei Hou

“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh by Sharmin Sultana, Md Shamsuzzaman, Md. Abdus Satter Miah, Akhter Jahan Kakon, Abdullah Hel Mafi, Anupoma Sen, Md. Nurealam Siddiqui, Debu Kumar Bhattacharjya

“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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Methodology for the identification of bioactive and marker peptides in the organs of cattle and pigs by D. V. Khvostov, N. L. Vostrikova, I. M. Chernukha

“…This category of these food-products is intended for personal  ized nutrition of various age groups in the population, taking into account fortification of the food with nutraceuticals and with functional and metabolically active ingredients obtained from animal and vegetable source. …”
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Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray by Yuncai Shen, Tingfeng Yi, Vinit Dhiman, Lisheng Mao, Liang Dong

“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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CoreTIA: a modular, statistically robust transduction inhibition assay for AAV neutralization by Beatrix Kovács, Beatrix Kovács, Beatrix Kovács, Fanni Somogyi, Fanni Somogyi, Viktória Szabó, Zoltán Zsolt Nagy, István Hernádi, Ferenc Mátyás, Wim Vanduffel, Zsuzsanna Szemlaky, Balázs Rózsa, Balázs Rózsa, István Ulbert, István Ulbert, István Ulbert, István Ulbert, Dániel Hillier, Dániel Hillier, Dániel Hillier

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Development of a Novel KCNN4-Related ceRNA Network and Prognostic Model for Renal Clear Cell Carcinoma by Hengtao Bu, Qiang Song, Jiexiu Zhang, Yuang Wei, Bianjiang Liu

“…Finally, quantitative real-time polymerase chain reaction and western blot were conducted for KCNN4 expression detection in cell lines and clinical samples. Small interfering RNA was employed to knock down KCNN4, and corresponding functional experiments were conducted on ccRCC cells as well. …”
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The burden of intracerebral hemorrhage attributable to ambient particulate matter pollution in five Asian countries: a 32-year comparative analysis by Rui Yang, Xingke Wang, Panpan Hao

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Preliminary Design of a GNSS Interference Mapping CubeSat Mission: JamSail by Luis Cormier, Tasneem Yousif, Samuel Thompson, Angel Arcia Gil, Nishanth Pushparaj, Paul Blunt, Chantal Cappelletti

“…First, a flexible, low-cost GNSS interference detection payload capable of characterising and geolocating the sources of radio interference regarding the E1/L1 and E5a/L5 bands will be demonstrated on a global scale. …”
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Double-moment normalization of hail size number distributions over Switzerland by A. Ferrone, J. Kopp, M. Lainer, M. Gabella, U. Germann, A. Berne

“…These results highlight the invariance of the normalized distribution and the adaptability of the method to different data sources.</p>…”
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THEORY AND PRACTICE OF ASSESSING THE LEVEL OF INSTABILITY OF THE EXTERNAL ENVIRONMENT OF THE ENTERPRISE IN A HYBRID WAR by I. Zapukhliak, A. Shegda, О. Mykytiuk, T. Onysenko, K. Petrenko

“…The article proposes a methodological approach to comprehensive assessment of the level of instability of environmental factors of enterprises, which, unlike others, involves the detection of instability in terms of seven components (socio-demographic, economic, technological, environmental, political, legal, ethical) on four criteria: complexity, interdependence, variability and uncertainty of factors, which makes it possible to determine their sources and nature, and thus form an effective response of the enterprise to change. …”
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Machine learning models for clinical and structural knee osteoarthritis prediction: Recent advancements and future directions by Gabby B. Joseph, Charles E. McCulloch, Michael C. Nevitt, Nancy E. Lane, Sharmila Majumdar, Thomas M. Link

“…These evolving strategies underscore the growing potential of ML to improve the detection of early OA, individualized risk stratification, and personalized interventions in OA clinical care.…”
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Sexual dysfunction in anxiety disorders by M. I. Yagubov, I. Yu. Kan, N. V. Dobaeva, I. R. Ayriyants

“…If sexual disorders are detected in patients with anxiety disorders, taking into account the clinical situation, psychotropic drugs with no or minimal negative effect on sexual function are prescribed, if possible. …”
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Worlds Next Door: A Candidate Giant Planet Imaged in the Habitable Zone of α Centauri A. II. Binary Star Modeling, Planet and Exozodi Search, and Sensitivity Analysis by Aniket Sanghi, Charles Beichman, Dimitri Mawet, William O. Balmer, Nicolas Godoy, Laurent Pueyo, Anthony Boccaletti, Max Sommer, Alexis Bidot, Elodie Choquet, Pierre Kervella, Pierre-Olivier Lagage, Jarron Leisenring, Jorge Llop-Sayson, Michael Ressler, Kevin Wagner, Mark Wyatt

“…Additionally, postprocessing with the principal-component-analysis-based Karhunen–Loéve image processing algorithm reveals a point source, called S 1, in 2024 August, detected at signal-to-noise ratio of 4–6 (3.3–4.3 σ ), a projected separation of ≈1 $\mathop{.}…”
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Renal Biopsy Pathological Tissue Segmentation: A Comprehensive Review and Experimental Analysis by Yan Liu, Taiping Wang, Xinxin He, Wei Wang, Qiang He, Juan Jin

“…This study provides a novel technical framework for precise renal pathological tissue segmentation and lays the foundation for future lesion detection and intelligent diagnostic applications.…”
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De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer <i>Azohydromonas lata</i> Strain H1 Genome and Genomic Analysis of PHB Production Machinery by Daniele Traversa, Carlo Pazzani, Pietro D’Addabbo, Lucia Trisolini, Matteo Chiara, Marta Oliva, Angelo Marzella, Camilla Mandorino, Carla Calia, Guglielmina Chimienti, Caterina Manzari, Graziano Pesole, Maria Scrascia

“…In addition to the <i>phaCAB</i> operon, single genes ascribable to PhaC and PhaA functions and auxiliary genes were also detected. A comparative genomic analysis of the available genomes of the genus <i>Azohydromonas</i> revealed the presence of <i>phaCAB</i> and auxiliary genes in all <i>Azohydromonas</i> species investigated, suggesting that the PHB production is a common feature of the genus. …”
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Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

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Historical traces in Southern Grevena during Ottoman occupation by Vasileios D. Spanos

“…In particular, attention was paid to the detection of all reports of the settlement, in written sources (published and unpublished), so that all the information concerning each settlement, even the simple reports, become known and accessible to the research and also in order to record all types with which each toponym is found, which also facilitates its etymology (although this identification was not always possible). …”
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Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria by Candice L. Wilshire, Carson C. Fuller, Christopher R. Gilbert, John R. Handy, Kimberly E. Costas, Brian E. Louie, Ralph W. Aye, Alexander S. Farivar, Eric Vallières, Jed A. Gorden

“…The electronic medical record (EMR) is a source of clinical information that could identify high-risk populations for LCS, including a diagnosis of COPD; however, an unsubstantiated COPD diagnosis in the EMR may lead to inappropriate LCS referrals. …”
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