Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Secondary outcomes included: unplanned 60- and 90-day hospital re-admissions; quality of transition; health-related quality of life (EuroQol-5 Dimensions, five-level version); and self-reported healthcare resource use. Data sources National Health Service Secondary Use Services data and Hospital Episodes data for work package 2 and routinely recorded National Health Service acute trust hospital data on re-admissions for work packages 5 and 6. …”
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Tracing the Earliest Stages of Star and Cluster Formation in 19 Nearby Galaxies with PHANGS-JWST and HST: Compact 3.3 μm Polycyclic Aromatic Hydrocarbon Emitters and Their Relation... by M. Jimena Rodríguez, Janice C. Lee, Remy Indebetouw, B. C. Whitmore, Daniel Maschmann, Thomas G. Williams, Rupali Chandar, A. T. Barnes, Oleg Y. Gnedin, Karin M. Sandstrom, Erik Rosolowsky, Adam K. Leroy, David A. Thilker, Hwihyun Kim, Jiayi Sun, Ralf S. Klessen, Brent Groves, Aida Wofford, Médéric Boquien, Daniel A. Dale, Leonardo Úbeda, Kirsten L. Larson, Kathryn Grasha, Kelsey E. Johnson, Rebecca C. Levy, Frank Bigiel, Hamid Hassani, Sumit K. Sarbadhicary

“…We establish a selection criteria based on a median color threshold of F300M − F335M = 0.67 at F335M = 20 and identify 1816 sources. These sources are predominantly located in dust lanes, spiral arms, rings, and galaxy centers, with ∼87% showing concentration indices (CIs) similar to optically detected star clusters. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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Comparing the Transcriptomes of Two Different Tissues in Helicoverpa assulta (Guenée) by Hailing Zhang, Kuiyin Li, Yubo Zhang

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Fish Diversity Patterns in Rivers Receiving Ecological Water Supplement Driven by Riparian Land Use by LIU Han, LI Lu-dan, GUO Wei-jie, QIAO Qiang-long, GONG Dan-dan, DU Qi, LI Hang, ZHAO Wei-hua

“…Functional dispersion (FDis) and taxonomic diversity (Delta) correlating significantly with all diversity dimensions (r=0.36-0.90; p<0.05) and outperforming species richness in detecting environmental responses. …”
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Characterization of Spectrin Family Genes and Their Evolutionary Roles in Domestication and Breeding of the Silkworm <i>Bombyx mori</i> by Kunpeng Lu, Chengyu Zhan, Jianghong Shen, Chao Zhi, Jun Deng, Kerui Lai, Minjin Han, Hai Hu, Xiaoling Tong, Fangyin Dai

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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Adolescent adaptive functioning was predicted not only by early childhood autistic symptoms and IQ and ADHD symptoms. …”
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Chi-circ_0009659 modulates goat intramuscular adipocyte differentiation through miR-3431-5p/STEAP4 axis by Xin Li, Hao Zhang, Yong Wang, Yanyan Li, Youli Wang, Yan Xiong, Wei Liu, Yaqiu Lin

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Integrated metabolomic and transcriptomic analyses of flavonoid accumulation in different cultivars of Platostoma palustre by Jiankai You, Zhongdong Wang, Lishan Zeng, Yimeng Xia, Ying Lin, Ruoting Zhan, Guifang Zhang

“…Abstract Background Platostoma palustre is a kind of plant resource with medicinal and food value, which has been differentiated into many different varieties after a long period of breeding. …”
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The Effect of Processing of Hempseed on Protein Recovery and Emulsification Properties by Anne Pihlanto, Markus Nurmi, Nora Pap, Jarkko Mäkinen, Sari Mäkinen

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Lower reclamation of coastal lagoon conserves higher waterbird assemblage phylogenetic diversity by Xianli Che, Min Zhang, Wangming Li, YanYan Zhao, Xuebing Zhao, Yisheng Peng, Alexandra Ashley Grossi, Zhaohui Pang, Fasheng Zou

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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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Characterization and Evolutionary Analyses Reveal Differential Selection Pressures on <i>PGIc</i> and <i>PGIp</i> During Domestication in Castor Bean by Jiayu Guo, Lanxin Jiang, Anmin Yu, Bing Han, Aizhong Liu

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Early Fault-Tolerant Quantum Algorithms in Practice: Application to Ground-State Energy Estimation by Oriel Kiss, Utkarsh Azad, Borja Requena, Alessandro Roggero, David Wakeham, Juan Miguel Arrazola

“…Additionally, we provide quantitative resource estimates, demonstrating a constant factor improvement in the number of samples required to detect a specified change in CDF. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Sample size An a priori sample size calculation of n = 380 dyads was computed as being sufficient to detect a standardised effect size of Cohen’s d = 0.4 for patient DASS-21 at 12 months post randomisation. …”
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Unravelling the Impact of an Additional Sex Chromosome in an Adult Female by Sigin George, Vikas Dagar, Barun Kumar Chakrabarty, N. Nagaraja

“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
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Effect of PM2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens by Lianlian Zhao, Xiaolin Ding, Li Zhou, Chenchen Song, Taisheng Kang, Yanfeng Xu, Yunpeng Liu, Yunlin Han, Wenjie Zhao, Boxiang Zhang, Dan Xu, Jianguo Guo

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Chromosome-level genome assembly of Phortica okadai, a vector of Thelazia callipaeda by Lingjun Wang, Hongsong Yu, Bo Luo, Rong Yan, Juan Zhou, Hui Liu, Ze Zhang, Wei Sun

“…Additionally, 302 rRNAs, 377 tRNAs, 52 miRNAs, 40 snRNAs and 21 snoRNAs were detected. In conclusion, this high-quality chromosome level reference genome will be a valuable resource for furthering the fields of ecology, genetics, evolution and functional genomics of P. okadai.…”
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Advanced Suspension Techniques in Interferometric Gravitational Wave Detectors: An Overview by Vishnu G. Nair

“…This isolation is crucial for enabling the detectors to function efficiently at low frequencies, which directly impacts their capacity to detect distant events from the universe’s past. …”
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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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