Lightweight deep learning system for automated bone age assessment in Chinese children: enhancing clinical efficiency and diagnostic accuracy by Pang Hai, Zhang Bin, Liu Kesheng, Li Cong, Xu Fei

“…In the first stage, the YOLOv8 algorithm precisely localizes 13 key epiphyses in hand radiographs, achieving a mean Average Precision (mAP) of 99.5% at Intersection over Union (IoU) = 0.5 and 94.0% within IoU 0.5–0.95, demonstrating robust detection performance. The second stage employs a modified EfficientNetB3 architecture for fine-grained epiphyseal grade classification, enhanced by the Rectified Adam (RAdam) optimizer and a composite loss function combining center loss and weighted cross-entropy to mitigate class imbalance. …”
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Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases by András Zeke, Tomas Bastys, Anita Alexa, Ágnes Garai, Bálint Mészáros, Klára Kirsch, Zsuzsanna Dosztányi, Olga V Kalinina, Attila Reményi

“…We used a structurally consistent model on kinase‐docking motif interactions to facilitate the discovery of short functional sites in the structurally flexible and functionally under‐explored part of the human proteome and applied experimental tools specifically tailored to detect low‐affinity protein–protein interactions for their validation in vitro and in cell‐based assays. …”
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Ethics of Sensor-Based Surveillance of People with Dementia in Clinical Practice by Jacob Lahr, Nicole Schulze, Larissa N. Wüst, Claus Beisbart, Lena C. Bruhin, Marcello Ienca, Tobias Nef, Manuel Trachsel, Stefan Klöppel

“…The level of privacy intrusion to detect occurring falls varies widely between different sensor systems. …”
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Roller-integrated compaction monitoring and assessment of high and low liquid limit silt subgrades using the Green spline interpolation algorithm by Yuchen Yan, Yanwen Zhu, Xian Yang, Lan Qiao, Chuping Wu, Zaizhan An, Qinglong Zhang, Ren Liu, Wang Guo

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Implementation of stochastic signal processing algorithms in radar CAD by M. Yu. Konopel'kin, S. V. Petrov, D. A. Smirnyagina

“…A simulation model of a sector surveillance radar with a digital antenna array was created in the radar CAD visual functional editor. The passive channel included the following algorithms: algorithm for detecting stochastic signals; algorithm for estimating the number of stochastic signals; direction finding algorithm for stochastic signal sources; adaptive spatial filtering algorithm. …”
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Neural Correlates of Changes in a Visual Search Task due to Cognitive Training in Seniors by Nele Wild-Wall, Michael Falkenstein, Patrick D. Gajewski

“…This study aimed to elucidate the underlying neural sources of near transfer after a multidomain cognitive training in older participants in a visual search task. …”
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A Gradient Grating Period Guided-Mode Resonance Spectrometer by Hsin-Yun Hsu, Yi-Hsuan Lan, Cheng-Sheng Huang

“…In this study, a GGP-GMR spectrometer less than 3 mm long that can achieve a wavelength detection range of 200 nm was demonstrated to reconstruct various incident spectra, including a single wavelength of light with a resolution of 0.5 nm, a single wavelength of light with varying intensity levels, and dual incident light sources.…”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Treatment with insulin is aimed at replicating the function of the pancreas to manage hyperglycaemia and avoid hypoglycaemia. …”
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A Novel Approach to Cognitive Load Measurement in N-Back Tasks Using Wearable Sensors, Empirical Mode Decomposition With Machine Learning, and Explainable AI for Feature Importance by Aakanksha Dayal, Ziaullah Khan, Kiramat Ullah, Hee-Cheol Kim

“…This study introduces a novel approach for detecting mental workload and stress, utilizing ECG and Fingertip-PPG data from the MAUS dataset. …”
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Discovery of Genomic Targets and Therapeutic Candidates for Liver Cancer Using Single-Cell RNA Sequencing and Molecular Docking by Biplab Biswas, Masahiro Sugimoto, Md. Aminul Hoque

“…This study aims to uncover key genomic features, analyze their functional roles, and propose potential therapeutic drugs identified through molecular docking, utilizing single-cell RNA sequencing (scRNA-seq) data from liver cancer studies. …”
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Origami-Inspired Biosensors: Exploring Diverse Applications and Techniques for Shape-Changing Sensor Platforms by Shikha Patil, Shariq Suleman, Nigar Anzar, Jagriti Narang, Roberto Pilloton, Suna Timur, Emine Guler Celik, Chandra S. Pundir, Sudheesh K. Shukla

“…Paper and biological substrates like DNA have been integrated with origami techniques to develop biosensors with enhanced functionality. The incorporation of aptamer origami into both paper and DNA biosensors further increases sensitivity and specificity for target detection. …”
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Efficient analysis of drug interactions in liver injury: a retrospective study leveraging natural language processing and machine learning by Junlong Ma, Heng Chen, Ji Sun, Juanjuan Huang, Gefei He, Guoping Yang

“…Electronic medical records contain comprehensive clinical information and have gained increasing attention as a potential resource for DDI detection. However, a substantial portion of adverse drug reaction (ADR) information is hidden in unstructured narrative text, which has yet to be efficiently harnessed, thereby introducing bias into the research. …”
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Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques by Renata F. Leoni, Kelley C. Mazzetto-Betti, Afonso C. Silva, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto

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Probing Cosmic Isotropy with the FAST All Sky H i Survey by Yi-Wen Wu, Jun-Qing Xia

“…This refined subsample is divided into 10 distinct sky regions, for which we compute the two-point angular correlation functions (2PACF) over angular scales of 0 $\mathop{.}…”
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Presepsin as a sepsis biomarker by K. A. Trunova

“…The measured  levels of presepsin are significantly influenced by renal function; therefore, in patients with renal disease, other sepsis markers should be used or the normal presepsin levels should be  adjusted to higher values. …”
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Assessing the Impact of Covid19-Pandemic on the Household Income in Kamuganguzi Sub-County Kabale District. by Arinda, Redeemer Present

“…Additionally, the government should establish a physical and automated platform for coordination and resource mobilization to support poor students and the most vulnerable groups affected by COVID-19-related lockdowns.…”
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Development of grain drink technology based on unsteamed buckwheat by G. M. Kerimova, I. A. Fomenko, A. R. Pivchenko, I. R. Sokolov

“…In the finished drink, the final indicators of the content of  protein, fat, reducing substances, dry substances have been detected. The finished product is also a source  of soluble dietary fiber, which has a positive effect on the human microbiome.…”
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Introducing the English EmpaToM task: A tool to assess empathy, compassion, and theory of mind in fMRI studies by Dorottya Lantos, Celeste Costa, Matthew Briglia, Pascal Molenberghs, Philipp Kanske, Tania Singer

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Levels of amino acids and homoarginine in the venous basins of the brain and the heart muscle in patients with ischemic heart disease by N. S. Molchan, T. Yu. Reypol'skaya, T. F. Subbotina, A. A. Zhloba, Yu. S. Polushin

“…Under the conditions of circulatory disorders and coronary heart disease (CHD), amino acids acquire additional value as a source of intermediates of Krebs cycle, participating in cell energetics. …”
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Enzymatic system of glucose metabolism in Gluconobacter oxydans strain DHA3-9 by Li Qianyan, Lu Xiangfeng, Zhang Pengcheng, Sun Lingyan, Liu Yu, Ma Xiaohang

“…Pyruvate and acetate were detected in the products of mutant whereas none of such products were found in wild type culture. …”
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