Discovery of candidate functional non-coding mutations in acute myeloid leukemia using single-cell chromatin accessibility sequencing by Ming Zhu, Jiali Zhu, Zhijuan Zhu, Yiding Yang, Jinxian Dai, Hua Li, Nainong Li, Jialiang Huang

“…Additionally, we develop eMut, an integrated computational pipeline for detecting, imputing, and functionally characterizing non-coding mutations in CREs at the single-cell level. …”
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AI-Driven Integration of Deep Learning With Lung Imaging, Functional Analysis, and Blood Gas Metrics for Perioperative Hypoxemia Prediction by Kecheng Huang, Chujun Wu, Rongpeng Pi, Jieyu Fang

“… This viewpoint article explores the transformative role of artificial intelligence (AI) in predicting perioperative hypoxemia through the integration of deep learning with multimodal clinical data, including lung imaging, pulmonary function tests, and arterial blood gas (ABG) analysis. …”
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Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer. by Andreas Rump, Anna Benet-Pages, Steffen Schubert, Jan Dominik Kuhlmann, Ramūnas Janavičius, Eva Macháčková, Lenka Foretová, Zdenek Kleibl, Filip Lhota, Petra Zemankova, Elitza Betcheva-Krajcir, Luisa Mackenroth, Karl Hackmann, Janin Lehmann, Anke Nissen, Nataliya DiDonato, Romy Opitz, Holger Thiele, Karin Kast, Pauline Wimberger, Elke Holinski-Feder, Steffen Emmert, Evelin Schröck, Barbara Klink

“…Ten out of eleven mutations that were tested exemplarily in cell-based functional assays exert diminished excision repair efficiency and/or decreased transcriptional activation capability. …”
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Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas. by Irina Haecker, Lauren A Gay, Yajie Yang, Jianhong Hu, Alison M Morse, Lauren M McIntyre, Rolf Renne

“…In summary, we provide an extensive list of cellular and viral miRNA targets representing an important resource to decipher KSHV miRNA function.…”
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Multi-layer feature fusion and attention-enhanced YOLOv9 for rapid field detection of greenhouse blueberry maturity at long and short distances by Ziwei Pan, Lei Xu, Wanjin Zhao, Cong Fan, Xihao Zhang, Weihui Chen, Yonglin Shen, Nengcheng Chen

“…Given the dense growth of blueberry plants and small fruit size, detecting blueberry maturity at long distances poses significant challenges. …”
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Industrial production and functional profiling of probiotic Pediococcus acidilactici 72 N for potential use as a swine feed additive by Nay Zin Myo, Ratchnida Kamwa, Benjamas Khurajog, Pawiya Pupa, Wandee Sirichokchatchawan, David J. Hampson, Nuvee Prapasarakul

“…Conventional and statistical optimization techniques were used to screen food-grade carbon sources (glucose, dextrose, sucrose) and nitrogen sources (beef extract, yeast extract, sweet whey) to develop the optimal formulation. …”
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Compact Laser-Induced Fluorescence Detector with Adjustable Laser Focal Spot for Multiple Purposes by Zihe Xu, Xi Chen, Fangwu Liu

“…The influence of the excitation power on the detection limit was studied through experiments, and the configuration results for LED/LD as light sources and 487/450 nm wavelengths were compared and optimized. …”
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The NASA Exoplanet Archive and Exoplanet Follow-up Observing Program: Data, Tools, and Usage by Jessie L. Christiansen, Douglas L. McElroy, Marcy Harbut, David R. Ciardi, Megan Crane, John Good, Kevin K. Hardegree-Ullman, Aurora Y. Kesseli, Michael B. Lund, Meca Lynn, Ananda Muthiar, Ricky Nilsson, Toba Oluyide, Michael Papin, Amalia Rivera, Melanie Swain, Nicholas D. Susemiehl, Raymond Tam, Julian van Eyken, Charles Beichman

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Enhanced high-sensitivity multi-layer neutron detector based on LiF:ZnS(Ag) scintillator by Ilan Cohen Zada, Alon Osovizky, Itzhak Orion

“…Each layer consists of a LiF: ZnS(Ag) scintillator coupled with a transparent neutron moderator that also functions as a light guide for the Silicon Photomultiplier (SiPM) light sensor. …”
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PATHOLOGICAL SIGNS OF EPILEPTIC AND NON-EPILEPTIC ORIGIN DETECTED IN AWAKE/SLEEP EEG PATTERNS DURING OUTPATIENT AND INPATIENT MONITORING: PROBLEMS OF INTERPRETATION by V. V. Gnezditskiy, O. S. Korepina, V. A. Karlov, G. B. Novoselova

“…Secondly, a loss of function can be caused by a continuous discharge activity of brain neurons. …”
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Regional Frequency Analysis Using L-Moments for Determining Daily Rainfall Probability Distribution Function and Estimating the Annual Wastewater Discharges by Pau Estrany-Planas, Pablo Blanco-Gómez, Juan I. Ortiz-Vallespí, Javier Orihuela-Martínez, Víctor Vilarrasa

“…RainFA is an easy-to-use and open-source software programmed using Python that can be applied anywhere in the world.…”
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Eeg-based detection of epileptic seizures in patients with disabilities using a novel attention-driven deep learning framework with SHAP interpretability by Tawfeeq Shawly, Ahmed A. Alsheikhy

“…Recent developments in artificial intelligence (AI) and deep learning have facilitated the automation of seizure detection from EEG signals with improved accuracy. …”
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Pulmonary function testing in pediatric allogeneic stem cell transplant recipients to monitor for Bronchiolitis obliterans syndrome: a systematic review by William A. Gower, Maximiliano Tamae-Kakazu, Shivanthan Shanthikumar, Saumini Srinivasan, Erin E. Reardon, Amisha V. Barochia, Edward Charbek, Charlotte Calvo, Pi Chun Cheng, Shailendra Das, Stella M. Davies, Jessica Gross, Ajay Sheshadri, Christoper T. Towe, Samuel B. Goldfarb, Narayan P. Iyer

“…Pulmonary function testing (PFT) pre- and post-aHSCT may allow for pre-symptomatic detection of BOS, and thus early intervention. …”
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High accuracy identification of maize seed varieties based on a lightweight improved YOLOv8 by Siqi Niu, Xiaolin Xu, Ao Liang, Yuliang Yun, Fengqi Hao, Jinqiang Bai, Wenyi Sheng, Dexin Ma

“…Lastly, the loss function was replaced with Inner_SIoU, which was more suitable for small-object detection tasks. …”
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Highly Efficient Biphoton Generation from Thin Dense Atomic Ensemble by Heewoo Kim, Hansol Jeong, Han Seb Moon

“…Strongly correlated bright biphotons are generated via spontaneous four‐wave mixing from a dense atomic ensemble based on the 6S1/2–6P3/2–6D5/2 transition of 133Cs. Biphoton source achieves a detected biphoton count rate of 100 kilo‐counts per second, a heralding efficiency of 15%, and a maximum normalized crosscorrelation function value of 100 between the signal and idler photons, despite the low detector efficiency of a silicon avalanche photodetector being less than 25% at 917 nm. …”
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An Embodied Intelligence System for Coal Mine Safety Assessment Based on Multi-Level Large Language Models by Yi Sun, Faxiu Ji

“…By leveraging the tool invocation and reasoning capabilities of LLM in conjunction with a coal mine safety knowledge base, the system achieves logical inference, anomalous data detection, and potential safety risk prediction. Furthermore, its memory functionality ensures the learning and utilization of historical experiences, providing a solid foundation for continuous assessment processes. …”
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The Impact of Differences in Renovation Models of Abandoned Boiler Rooms on Community Vitality—A Case Study of Shenyang, China by Lei Chen, Yahang Cheng, Zixi Zhou, Yibo Wen

“…Unlike prior studies that rely on single data sources or unidimensional metrics, our multi-source approach enhances spatiotemporal resolution, improves the accuracy of subjective perceptions, and enables cross-validation between objective behavioral trajectories and residents’ self-reports, thereby significantly strengthening the comprehensiveness and reliability of community vitality measurement. …”
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Ibai mag blinds blindana tiuhan? (Luke 6,39). Pragmatic functions and syntactic strategies in the Gothic left sentence periphery by Marina Buzzoni

“…On the basis of the consideration – corrobora ted through interlinguistic comparison – that the discourse layer finds a specific formalization in the syntactic structure, the main aim of the present study is to investigate how and to what extent a different pragmatic function of the aforementioned elements correlates with a specific syntactic representation. …”
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Ibai mag blinds blindana tiuhan? (Luke 6,39). Pragmatic functions and syntactic strategies in the Gothic left sentence periphery by Marina Buzzoni

“…On the basis of the consideration – corrobora ted through interlinguistic comparison – that the discourse layer finds a specific formalization in the syntactic structure, the main aim of the present study is to investigate how and to what extent a different pragmatic function of the aforementioned elements correlates with a specific syntactic representation. …”
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An innovative and mass-sensitive quartz tuning fork (QTF) biosensor for GFAP detection: A novel approach for traumatic brain injury diagnosis by Burcu Özcan, İnci Uludağ Anıl, Mehmet Altay Ünal, Fikret Arı, Mustafa Kemal Sezgintürk, Sibel Ayşıl Özkan

“…This biosensor is designed to facilitate the highly sensitive and selective detection of GFAP in human serum. In contrast to conventional neuroimaging methods, which are resource-intensive and frequently inaccessible in emergency situations, this innovative biosensor offers a portable, cost-effective, and efficient alternative for rapid GFAP measurement. …”
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