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Chromosome-level genome assembly of starry flounder (Platichthys stellatus)
Published 2025-07-01“…Approximately 94.02% of assembled sequences were anchored into 24 pseudochromosomes, and a total of 18 telomeres were detected. Totally 22,835 protein-coding genes and 227.87 Mb repetitive sequences were identified. …”
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Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
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1343
The Roles of Transcrustal Magma- and Fluid-Conducting Faults in the Formation of Mineral Deposits
Published 2025-05-01“…At hydrocarbon fields, they play extremely important roles in conductive and convective heat, as well as in mass transfer to the area of hydrocarbon generation, determining the relationship between the processes of lithogenesis and tectogenesis, and activating the generation of hydrocarbons from oil and gas source rock. Detection of TCMFCFs was carried out using MMSS (the method of microseismic sounding) and MTSM (the magnetotelluric sounding method), in combination with other geological and geophysical data. …”
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1344
Renal Biopsy Pathological Tissue Segmentation: A Comprehensive Review and Experimental Analysis
Published 2025-01-01“…This study provides a novel technical framework for precise renal pathological tissue segmentation and lays the foundation for future lesion detection and intelligent diagnostic applications.…”
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Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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NORDIC denoising on VASO data
Published 2025-01-01“…However, VASO comes along with another reduction in detection sensitivity. NOise Reduction with DIstribution Corrected (NORDIC) PCA (principal component analysis) is a denoising technique specifically aimed at suppressing thermal noise, which has proven useful for increasing the SNR of high-resolution functional data. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation
Published 2025-05-01“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean
Published 2023-03-01“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
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Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors
Published 2025-05-01“…Then calculate the correlation function of the reconstructed signal echo and apply a smooth pseudo Wigner Ville distribution for time-frequency analysis. …”
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Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples
Published 2025-03-01“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction
Published 2023-07-01“…Special research methods included the assessment of the state of the microbicidal function of neutrophilic granulocytes using reactive spontaneous (SSLCL) and zymosan-induced luminol-dependent chemiluminescence tests (ILZHL). …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis
Published 2025-08-01“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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Chemometrically assisted optimization and validation of the HPLC method for the analysis of alectinib and its related impurity with measurement uncertainty evaluation and whiteness...
Published 2025-05-01“…This made it possible to find and measure the sources of uncertainty as well as the factors that affected the chromatographic responses. …”
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Personality and Personality Disorders in Medication-Overuse Headache: A Controlled Study by SWAP-200
Published 2019-01-01“…At levels of specific PDs, MOH patients showed higher obsessive and dysphoric traits and better overall psychological functioning than SUD and PD patients. Conclusion. Although MOH, SUD, and PD populations have been evaluated in multiple sites with different levels of expertise, the study supported the presence of a specific constellation of personality in MOH patients including obsessive (perfectionist) and dysphoric characteristics, as well as good enough psychological resources. …”
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Health-related quality of life, physical and mental capacity at one year follow up of COVID-19 ICU patients: A prospective cohort study
Published 2025-05-01“…Abstract Purpose In 2020 as COVID-19 rapidly overwhelmed ICU resources, patient care capacity was reduced thus increasing the risk of development of post intensive care syndrome (PICS). …”
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Predicting the course of localized periodontitis of traumatic etiology after complex treatment
Published 2024-03-01“…We employed clinical, radiological, and functional methods of examining periodontal condition, and investigated laboratory blood parameters (complete blood count, C-reactive protein). …”
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