Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t... by Mário Henrique Girão Faria, Régia Maria do Socorro Vidal do Patrocínio, Manoel Odorico de Moraes Filho, Silvia Helena Barem Rabenhorst

“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury by Ting Zhou, Ziyao Zhang, Yawen Zhan, Meiying Wang, Meiying Wang, Meiying Wang, Mi Wu, Xiufang Weng, Xiufang Weng, Xiufang Weng, Xiufang Weng, Younian Xu, Younian Xu, Younian Xu

“…The ratio, number, phenotype, and function of immune cells and cytokine levels were measured. …”
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Venous Thromboembolism Prophylaxis in Intensive Care Units (Review) by L. V. Popova, T. B. Kondratieva, M. Z. Kanevskaya, T. L. Aleinikova, E. S. Zykova, А. V. Krivova, A. M. Kuznetsov

“…VTE is common and potentially life-threatening in patients admitted to ICU, even in spite of preventive care.The purpose of the review is to justify the necessity of preventive care for venous thromboembolism in ICU patients.From over 300 initially selected sources of literature databases (Scopus, Web of science, RSCI, etc.), 99 sources were chosen including 69 that were published during the last five years (2015-2020). …”
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Antioxidant Activity and Potential Bioactive Peptides from Skin Protein Hydrolysate of Yellowfin Tuna (<I>Thunnus albacares</I>) by Sitti Hardiyanti Rachman, Joko Santoso, Sugeng Heri Suseno

“…FPH possesses a molecular weight of 10.15-48.50 kDa. Functional groups detected were amides A, B, I, II, and III. …”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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DUALZ—Deep UNCOVER-ALMA Legacy High-Z Survey by Seiji Fujimoto, Rachel Bezanson, Ivo Labbe, Gabriel Brammer, Sedona H. Price, Bingjie Wang, John R. Weaver, Yoshinobu Fudamoto, Pascal A. Oesch, Christina C. Williams, Pratika Dayal, Robert Feldmann, Jenny E. Greene, Joel Leja, Katherine E. Whitaker, Adi Zitrin, Sam E. Cutler, Lukas J. Furtak, Richard Pan, Iryna Chemerynska, Vasily Kokorev, Tim B. Miller, Hakim Atek, Pieter van Dokkum, Stéphanie Juneau, Susan Kassin, Gourav Khullar, Danilo Marchesini, Michael Maseda, Erica J. Nelson, David J. Setton, Renske Smit

“…Through a blind search, we identified 69 dust continuum sources at a signal-to-noise ratio (SNR) ≳ 5.0 with median redshift and intrinsic 1.2 mm flux of z = 2.30 and ${S}_{{\rm{1.2mm}}}^{{\rm{int}}}=0.24$ mJy. …”
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The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i> by Liang Wu, Yong Xu

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Unraveling the microbiome–aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars by Jing Pan, Ming-Da Huang, Jin Wang, Jian-Xiong Zhao, Bin Yang, Hong-Hui Yang, Jin-Sheng Huang, Yu-Long Su, Xue-Ru Song, Wei-Guang Wang, Ling-Duo Bu

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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han

“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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Profiling of rhizosphere-associated microbial communities in North Alabama soils infested with varied levels of reniform nematodes by Sowndarya Karapareddy, Varsha C. Anche, Sowjanya R. Tamatamu, Madhusudhana R. Janga, Kathy Lawrence, Leopold M. Nyochembeng, Antonette Todd, Lloyd T. Walker, Venkateswara R. Sripathi

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De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii by Valentina Mastrantonio, Daniele Porretta, Franco Liberati, Roberta Bisconti, Tiziana Castrignanò, Daniele Canestrelli

“…Validation by BUSCO confirmed the high quality of our resources. Homology alignments of predicted ORFs showed that 21,842 sequences from Ae. mariae and 21,944 sequences from Ae. zammitii mapped to the Nr, SwissProt, and TrEMBL databases, while 19,208 and 19,393 predicted ORFs, respectively, were functionally annotated using the COG and KEGG databases. …”
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Protective effects of Maillard products of skipjack trypsin hydrolysate on uric acid-induced injury of human kidney-2 cell (HK-2) by Yurou Chu, Jiaxing Wang, Jipeng Sun, Ru Song, Liang Chen, Xiaoyu Zou

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The biocontrol effects and mechanisms of mycoparasitic Alternaria alternata against Chinese rose powdery mildew by Yanping Tang, Yanping Tang, Ruotian Gao, Ruotian Gao, Changle Ma, Jin Wang, Jing Li, Jing Li

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Unravelling the Impact of an Additional Sex Chromosome in an Adult Female by Sigin George, Vikas Dagar, Barun Kumar Chakrabarty, N. Nagaraja

“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
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In-band network telemetry system based on high-performance packet processing architecture VPP by Tian PAN, Xingchen LIN, Jiao ZHANG, Tao HUANG, Yunjie LIU

“…An in-band network telemetry-based system was built based on VPP, a high-performance virtual network forwarding architecture/device, via reorganizing the data plane pipeline processing modules.Moreover, a network-wide telemetry mechanism was further developed via embedding source routing into the probe packet header for specifying the route of probe packets.Finally, a virtual network topology was built with performance evaluation conducted.The evaluation shows that the telemetry system can monitor the network in a high precision of every 0.13 ms, detecting link congestion in real time with minor performance overhead.Given virtual network devices have been widely deployed in data centers, the proposed scheme is expected to improve the reliability of multi-tenancy and network function virtualization in data centers via high-precision, network-wide virtual link telemetry coverage.…”
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Who Leads Trends on Q&A Platforms? Identifying and Analyzing Trend Discoverers by Yongning Li, Lun Zhang, Ye Wu, Tianlan Wei

“…Q&A platforms are vital sources of information but often face challenges related to their high ratios of passive to active contributors, which can impede knowledge construction and information exchange on the platforms. …”
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Splicing defect of StDRO2 intron 1 promotes potato root growth by disturbing auxin transport to adapt to drought stress by Jianping Zhao, Baolin Yao, Ziai Peng, Xinyue Yang, Kuixiu Li, Xiaoyan Zhang, Haiyan Zhu, Xuan Zhou, Meixian Wang, Lihui Jiang, Xie He, Yan Liang, Xiaoping Zhan, Xiaoran Wang, Yuliang Dai, Yanfen Yang, Ao Yang, Man Dong, Suni Shi, Man Lu, Yi Zhao, Mingyun Shen, Liwei Guo, Changning Liu, Hongji Zhang, Decai Yu, Yunlong Du

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Spatial Variability and Periodicity of Precipitation in the Middle Reaches of the Yellow River, China by Yi He, Xingmin Mu, Peng Gao, Guangju Zhao, Fei Wang, Wenyi Sun, Yuqing Zhang

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Validation of a 60K SNP chip for caribou (Rangifer tarandus) for use in wildlife forensics, conservation, and management by Trottier-Lavoie Mallorie, Prunier Julien, Poisson William, Carrier Alexandra, Gilbert Isabelle, Mastromonaco Gabriela, Albert Vicky, Cecilia Hernandez, Bourret Vincent, Taillon Joëlle, Droit Arnaud, Côté Steeve D., Robert Claude

“…The SNP chip was shown to be robust, highly sensitive, reliable, and accurate at more than 10-fold below the recommended DNA input. Biological source of DNA had minor impact, even with fecal pellets given sufficient amount of host DNA. …”
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Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China by Hui Jin, Hui Jin, Cong Wang, Cong Wang, Yi-Yue Yang, Yi-Yue Yang, Lie Zhou, Lie Zhou, Yun Xiao, Yun Xiao, Yang Wen, Yang Wen, Jawad Ahmad, Jawad Ahmad, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Ming Li, Wei Luo, Xiao-Fei Zhou, Jian-Jun Luo, Bo Liu, Eric Yu-Hai Chen, Mao-Sheng Ran, Mao-Sheng Ran

“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
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