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C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS‐STING Pathway
Published 2025-01-01“…Histopathological examination, level of inflammation, cGAS‐STING pathway, and gut barrier function were detected in mice and cells. Results C9orf72 overexpression in mice attenuated DSS‐induced colitis and intestinal epithelial barrier damage by stimulating ZO‐1 and Occludin expression. …”
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1662
Endodontic treatment of teeth with a wide apical opening – a clinical case
Published 2025-06-01“…The presented clinical case demonstrates the successful endodontic treatment of a tooth in a teenager, in which treatment tactics aimed at stimulating apexification were applied. …”
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1663
Development of a Rapid UPLC Method for Analysis of Carotenoids in Goji Berry Extract and Evaluation of Their Transformation Affected by Saponification
Published 2024-11-01“…This method successfully separates 17 carotenoids and their esters within 21 min using a Sunrise C30 column, with detection at 450 nm, a flow rate of 1.3 mL/min, and a column temperature of 25 °C. …”
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1664
Cloning and expression analysis of sugar transporter protein gene MeSWEET17b in cassava
Published 2024-12-01Get full text
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1665
Genomics and integrative clinical data machine learning scoring model to ascertain likely Lynch syndrome patients
Published 2025-05-01“…Annovar, Intervar, Variant Effect Predictor (VEP), and OncoKB software tools were used to functionally annotate and interpret somatic variants detected. …”
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1666
The battle between rotavirus and its host for control of the interferon signaling pathway.
Published 2013-01-01“…Viral pathogens must overcome innate antiviral responses to replicate successfully in the host organism. Some of the mechanisms viruses use to interfere with antiviral responses in the infected cell include preventing detection of viral components, perturbing the function of transcription factors that initiate antiviral responses, and inhibiting downstream signal transduction. …”
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1667
The Diversity of Cold Worlds: A Blended-light Binary Straddling the T/Y Transition in Brown Dwarfs
Published 2025-01-01“…Carbon disequilibrium chemistry strongly shapes the mid-infrared spectra of these sources, as a complex function of the metallicity and surface gravity. …”
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1668
A data driven approach using local measurements to locate turbine governors causing forced oscillations
Published 2025-07-01“…When forced oscillations are detected, they are located by finding the transfer functions that describe the behaviour of the corresponding plant the worst. …”
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1669
INDICATORS AND CRITERIA FOR ASSESSMENT OF MULTIFUNCTIONAL DEVELOPMENT OF RURAL TERRITORIES
Published 2018-05-01“…The authors identify five basic functions of rural areas, developed and presented by the author’s methodology for monitoring the dynamic and including thirty-one indicators, which allow to assess the changes in rural area over the years.Discussion. …”
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1670
Inference of a plume conduit beneath the Réunion Island from 3D migration of Ps conversions from the mantle transition zone
Published 2025-03-01“…In this study, we investigate the mantle transition zone (MTZ) structure beneath the Réunion Island using 3D-migration of P-Receiver functions, to decipher the effect of the plume on the MTZ and its architecture. …”
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1671
Urotensin-II: More Than a Mediator for Kidney
Published 2012-01-01“…Although both hU-II and its receptor, GPR14, are detected in several tissues, kidney is a major source of U-II in humans. …”
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1672
GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization
Published 2025-05-01“…We optimized assay conditions and developed an all-in-one vector employing cloning methods to ensure the correct expression ratio of GzESTY components. GzESTY successfully assessed activation of a library of ligand-activated GPCRs, detecting both full and partial agonism, and responses from endogenous GPCRs. …”
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1673
PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure.
Published 2009-07-01“…Therefore, computational methods which, given a set of 3D coordinates, can automatically identify and describe channels in transmembrane proteins are key tools to provide insights into how they function.Herein we present PoreWalker, a fully automated method, which detects and fully characterises channels in transmembrane proteins from their 3D structures. …”
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1674
Sunlight Noise Mitigation in FMCW LiDAR Using FADOF
Published 2024-01-01“…Additionally, the system achieves a detection range of at least 17 meters under direct sunlight conditions. …”
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1675
One-Step Solvothermal Synthesis of Carbon Dots for Rapid and Accurate Determination of Hemin Content
Published 2025-03-01“…The linear regression equation was (1 − <i>F</i>/<i>F</i><sub>0</sub>) = 0.0897<i>c</i> + 0.0124, with a correlation coefficient (<i>R</i><sup>2</sup>) of 0.9982 and a detection limit of 9 nM. This assay was successfully used to determine the content of hemin in the tablet, which displayed 97.9–105.5% of the labelled amount, with a relative standard deviation of less than 3%. …”
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1676
Microwave Ablation for Renal Cell Carcinoma: A Literature Review and Clinical Insights
Published 2025-04-01“…Independent of the type of thermal ablation techniques used, there are important technical considerations for the successful destruction of targeted tumours while minimising complications, including the use of ultrasound for antenna placement and ablation monitoring, immediate post-procedure contrast-enhanced CT for detection of incomplete treatment and early detection of complications, and hydrodissection and hydroureter for prevention of intraprocedural complications. …”
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1678
Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction.
Published 2016-07-01“…To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two budding yeast strains. This phenotype is detectable when certain segregants are grown on ethanol at 37°C ('E37'), a condition that differs from the standard culturing environment in both its carbon source (ethanol as opposed to glucose) and temperature (37°C as opposed to 30°C). …”
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1679
Rotor Location During Atrial Fibrillation: A Framework Based on Data Fusion and Information Quality
Published 2025-03-01“…The proposed framework outperformed existing EGM-based rotor detection methods, demonstrating superior functionality and performance compared to existing EGM-based rotor detection methods. …”
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1680
Presepsin as a sepsis biomarker
Published 2018-05-01“…Presepsin was highly sensitive in detecting late neonatal sepsis, burn sepsis, and also reflected the efficacy of therapy in septic premature babies and severely burned patients. …”
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