Biomarkers of cellular senescence predict risk of mild cognitive impairment: Results from the lifestyle interventions for elders (LIFE) study by Michelle M. Mielke, Roger A. Fielding, Elizabeth J. Atkinson, Zaira Aversa, Marissa J. Schafer, Steven R. Cummings, Marco Pahor, Christiaan Leeuwenburgh, Nathan K. LeBrasseur

“…Most studies of the SASP have focused on frailty and other functional outcomes. Senescent cells have been detected in the brains of patients with Alzheimer’s disease, but few studies have examined associations between plasma SASP markers and cognition. …”
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Identification of WRKY gene family and analysis of drought stress expression in Poncirus polyandra by ZHANG Shanshan, RUAN Sunmei, YANG Wenzhong

“…This study provides new information for analysing the function of WRKY gene and its regulatory mechanism in response to drought stress in P. polyandra, and supplies excellent genetic resources for breeding drought-tolerant citrus varieties.…”
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Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway by Qiuhong Jiao, Xiufeng Xu, Longwu Xu, Yuying Wang, Shulan Pang, Jie Hao, Xiaohong Liu, Yudan Zhao, Wanpeng Qi, Limin Qin, Tao Huang, Jingtian Li, Tao Wang

“…Double-labeled immunofluorescence showed eIF3a was mostly co-localized with CD31, this result indicated that the development of MCT-induced PAH was related to the regulation of PAECs function (most likely associated with the change of EndMT in endothelial cells). …”
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Evaluating the Pattern of Forest Cover Changes Using Fuzzy Object-Oriented Techniques (Case Study: Kaleybar County) by Majid Pishnamaz Ahmadi, keyvan Mohammadzadeh, seyed Asadolah Hejazi

“…In order to obtain a proper planning and management for natural resources, especially forests, accurate and timely information maps are required. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Sample size An a priori sample size calculation of n = 380 dyads was computed as being sufficient to detect a standardised effect size of Cohen’s d = 0.4 for patient DASS-21 at 12 months post randomisation. …”
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