QbD-steered HPTLC approach for concurrent estimation of six co-administered COVID-19 and cardiovascular drugs in different matrices: greenness appraisal by Ahmed R. Mohamed, Rania A. Sayed, Abdalla Shalaby, Hany Ibrahim

“…On HPTLC-silica plates, the above-mentioned medications were separated utilizing an eluent system of ethyl acetate, methylene chloride, methanol, and ammonia (6:4:4:1 by volume), and their spots were detected at 232 nm. The proposed methodology was evaluated following ICH prerequisites and applied successfully to the medications’ dosage forms, human plasma, and buffered dissolution media with superb recovery proportions and no intrusiveness from formulations’ additives or plasma matrices. …”
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Responsive to adaptive supramolecular hydrogels for diabetic wound treatment by Shalini Balakrishnan, Revathy Remesh, Krishnan Kartha Kalathil, Anie Y

“…In this review, we look into the recent developments in the fabrication of smart supramolecular hydrogels that detect the physiological changes in diabetic wound and adapt to the environment by undergoing structural or functional changes that are important in tackling many issues related to diabetic wound treatment.…”
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Transcriptional patterns of cancer-related genes in primary and metastatic tumours revealed by machine learning by Faeze Keshavarz-Rahaghi, Erin Pleasance, Steven J. M. Jones

“…Results Using random forest models, we successfully identified transcriptional patterns associated with the loss of wild-type activity in cancer-related genes across various tumour types. …”
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Use of Cidofovir for Safe Transplantation in a Toddler with Acute Liver Failure and Adenovirus Viremia by Vikram J. Christian, Raiya Sarwar, Joseph C. Resch, Sarah Lim, Arif Somani, Catherine Larson-Nath, Shane McAllister, Beth K. Thielen, Oyedele Adeyi, Srinath Chinnakotla, Heli Bhatt

“…Our patient received a successful liver transplant, cleared the viremia after 5 doses of cidofovir, and continues to maintain allograft function without signs of infection at the time of this report, 5 months posttransplant. …”
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Mixed eco-neighborhood: Matsaria as a model of post-industrial transformation by Iñigo Garcia Odiaga, Nekane Azpiazu Lejardi, Francisca Gual Ors

“…These guidelines arise from common patterns detected in successful processes of urban and industrial regeneration, demonstrating their capacity for transformation in non-specialized structures. …”
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Visualization of Molluscum Contagiosum Virus in FFPE Skin Sections Using NanoSuit‐CLEM: Ultrastructural Evidence of Viral Spread via Skin Barrier Disruption by Yuri Sakano, Hideya Kawasaki

“…While Melan‐A immunostaining successfully detected Henderson–Patterson bodies, it failed to identify mature MC virus particles. …”
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Geometric morphometric analysis of the condylus occipitalis and foramen magnum in sheep and goat by Ismail Demircioglu, Yasin Demiraslan, Funda Aksunger Karaavci, Iftar Gurbuz, Ozcan Ozgel

“…<p> <b>Conclusion: </b>As a result, the geometric morphometry method is regarded to be a useful tool for detecting changes in skull shape between species and can thus be used successfully for taxonomic, archaeological, and forensic research.…”
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Genome-wide association mapping of aluminum toxicity tolerance and fine mapping of a candidate gene for Nrat1 in rice. by Yonghong Tao, Yanan Niu, Yun Wang, Tianxiao Chen, Shahzad Amir Naveed, Jian Zhang, Jianlong Xu, Zhikang Li

“…A total of 21 putative QTL affecting shoot height (SH), root length (RL), shoot fresh weight (SFW), shoot dry weight (SDW), root dry weight (RDW) and shoot water content (SWC) were identified at seedling stage, including three QTL detected only under control condition, eight detected only under Al stress condition, ten simultaneously detected in both control and Al stress conditions, and seven were identified by stress tolerance index of their corresponding traits. …”
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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Pacemaker migration into the peritoneal cavity in children: a case series by Nicole H. Chicoine, Patrick J. Javid, David H. Rothstein, Samuel E. Rice-Townsend, Kimberly J. Riehle, Terrence U. Chun, Sarah L.M. Greenberg

“…Migration was detected at the age of 17 years on a routine abdomen/chest x-ray, and was confirmed on a CT. …”
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Preparation of nanosized hypoxia-inducible factor 1α inhibitor and its application in reversing chemoresistance in colorectal cancer cells by ZHENG Chuanhao, DAN Ruijue, XI Xi

“…FYC-1 was also successfully prepared. When FYC-1 was interacted with HCT15 cells, FYC-1 could be better taken up by the cells, indicating that the amphiphilic MYC-1 could be better endocytosed into the cells to exert its function. …”
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The effect of PLGA-PEG-PLGA modification on the sol-gel transition and degradation properties by J. Oborna, L. Mravcova, L. Michlovska, L. Vojtova, M. Vavrova

“…Itaconic acid, obtained from renewable resources, delivers a reactive double bond and carboxylic functional group to the end of PLGA-PEG-PLGA copolymer: this is important for a reaction with biologically active substances. …”
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Reactions of Citrullus amarus and Cucumis metuliferus to Meloidogyne chitwoodi, Meloidogyne enterolobii and Meloidogyne luci by Aida Magdalena FULLANA, Carla MALEITA, Duarte SANTOS, Isabel ABRANTES, Francisco Javier SORRIBAS, Ariadna GINÉ

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Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9 by Advaita Acarya Singh, Advaita Acarya Singh, Priyen Pillay, Previn Naicker, Kabamba Alexandre, Kanyane Malatji, Lukas Mach, Herta Steinkellner, Juan Vorster, Rachel Chikwamba, Tsepo L. Tsekoa

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Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques by Renata F. Leoni, Kelley C. Mazzetto-Betti, Afonso C. Silva, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto

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Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media by Humaira Yasmin, Rawan Bossly, Fuad S. Alduais, Afrah Al-Bossly, Anwar Saeed

“…The analysis is done via the bvp4c MATLAB function in order to analyze the current model numerically by implementing convective boundary conditions. …”
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Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…Among T cells, particularly, Pdcd1+ γδ T cells were detected in necrotizing granulomatous lesions, suggesting their potential role in the pathogenicity of M. tuberculosis. …”
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Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh by Sharmin Sultana, Md Shamsuzzaman, Md. Abdus Satter Miah, Akhter Jahan Kakon, Abdullah Hel Mafi, Anupoma Sen, Md. Nurealam Siddiqui, Debu Kumar Bhattacharjya

“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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Role of Polyphosphate as an Inorganic Chaperone to Prevent Protein Aggregation Under Copper Stress in <i>Saccharolobus solfataricus</i> by José Acevedo-López, Gabriela González-Madrid, Claudio A. Navarro, Carlos A. Jerez

“…They are present across all life domains, serving as a source of energy, metal chelators, and playing a crucial role in stress defense. …”
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On Explainability of Reinforcement Learning-Based Machine Learning Agents Trained with Proximal Policy Optimization That Utilizes Visual Sensor Data by Tomasz Hachaj, Marcin Piekarczyk

“…This estimation makes it possible to determine whether the network makes decisions as expected (decision-making is related to the model’s observation of objects belonging to different semantic classes in the environment) and to detect unexpected, seemingly chaotic behavior that might be, for example, the result of data bias, bad design of the reward function or insufficient generalization abilities of the model. …”
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