Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible by Qingge Guo, Xiuxiu Jin, Xiaoyu Xin, Xiaohong Guo, Shuai Ming, Yuxiang Li, Bo Lei

“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
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The Ultrastructure of Olfactory Sensilla Across the Antenna of <i>Monolepta signata</i> (Oliver) by Jiyu Cao, Wanjie He, Huiqin Li, Jiangyan Zhu, Xiaoge Li, Jiahui Tian, Mengdie Luo, Jing Chen

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Establishment of genetic transformation system and initial report of transform BIO and bio gene in Petunia hybrida by LI Ying, LIU Jiyan, HU Jiangqin, CHEN Zhehao, HU Lingzhi, WANG Lilin

“…MS medium with 1.0 mg/L 6-BA and 0.1 mg/L NAA was best for the bud regeneration. 0.3 mg/L hygromycin was used for resistance screening and 20 different resistant plants were obtained for both BIO and its mutant gene bio respectively. PCR detection of gene expression showed that 15 35S-BIO and 17 35S-bio transgenic plants had been successfully obtained. …”
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Transcriptomic Analysis Reveals the Biosynthesis Mechanism of Coixol Under Salicylic Acid Treatment by Yao Wang, Hanli Ye, Xuqin Luo, Ziwei Li, Chuanqi Zheng, Dali Sun

“…Background: Coix (<i>Coix lacryma-jobi</i> L.) is cultivated as medicine and food homologous resources containing various active components. As one of its main ingredients, coixol possesses the biological activities of fever reduction, pain relief, tumor suppression, blood glucose, and pressure decrease. …”
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Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism by Weronika Marynowicz, Paulina Głód, Dawid Maduzia, Justyna Gogola-Mruk, Anna Ptak

“…Occult POI (oPOI), an initiating form, is more challenging to detect but still allows potential success with IVF. …”
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The development of a story recall test for distinguishing between Alzheimer’s disease and mild cognitive impairment in Thai cohort by Natinee Na Chiangmai, Peera Wongupparaj, Pattrawadee Makmee, Claudio Mulatti, Remo Job

“…Further analysis revealed that delayed recall, backward digit span, and letter fluency tasks could significantly contribute to a discriminant function. It successfully classified participants with cognitive impairment (MCI and AD together) with an accuracy of 0.87, a sensitivity of 83.3%, and a specificity of 77.1%. …”
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Sparse Inversion of Gravity and Gravity Gradient Data Using a Greedy Cosine Similarity Search Algorithm by Luofan Xiong, Zhengyuan Jia, Gang Zhang, Guibin Zhang

“…To further enhance the stability and accuracy of the inversion process, a pruning mechanism is introduced to dynamically detect and remove erroneously selected cells, thereby suppressing error propagation. …”
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Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-181c-5p Promote BMP2-Induced Repair of Cartilage Injury through Inhibition of SMAD7 Expr... by Qiang Zhang, Le Cao, Shanqi Zou, Yuanling Feng, Xudong Miao, Lu Huang, Yongping Wu

“…Herein, we tried to analyze the role of human umbilical cord MSC- (hUCMSC-) EVs carrying microRNA- (miR-) 181c-5p in repair of cartilage injury. After successful isolation of hUCMSCs, the multidirectional differentiation abilities were analyzed. …”
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Anti-corruption management in the health care system: the legal aspect by М. А. Anishchenko

“…Analyzing the current legal acts, anti-corruption management includes the following main areas of activity (functions): determination of the person (unit) responsible for preventing and detecting corruption in the health care establishment and creating the necessary conditions for its (her) successful work; development and approval of the necessary internal documents on issues of anti-corruption activities, their constant and timely updating; implementation of anti-corruption legislation in other internal documents of the health care institution; realization of corruption risk assessment; ensuring proper prevention and conflict resolution of interests; ensuring openness and transparency of the health care institution's activities; organization of anti-corruption education of employees of the institution of health care; the proper management of information on corruption offenses; maintenance of the necessary registers and databases; control and monitoring of the effectiveness of anti-corruption measures. …”
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Lung cancer intravasation-on-a-chip: Visualization and machine learning-assisted automatic quantification by Christy Wing Tung Wong, Joyce Zhi Xuen Lee, Anna Jaeschke, Sammi Sze Ying Ng, Kwok Keung Lit, Ho-Ying Wan, Caroline Kniebs, Dai Fei Elmer Ker, Rocky S. Tuan, Anna Blocki

“…Wihin 24 h of exposure, EMT-IC facilitated the insertion of membrane protrusions of migratory A549 cells into microvascular structures, followed by successful intravasation. EMT-IC reduced key basement membrane and vascular junction proteins - laminin and VE-Cadherin - rendering vessel walls more permissive to intravasating cells. …”
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IT GOVERNANCE IN THE BANKING SECTOR: EVIDENCE FROM ITALY, GERMANY, FRANCE AND SPAIN by Ida Claudia Panetta, Sabrina Leo, Fabrizio Santoboni, Gianfranco Vento

“…IT is an intrinsic component of banks’ operational functioning; it is a key resource in developing and supporting banking services, enabling institutions’ strategies, and it is essential for almost all banking processes and distribution channels. …”
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Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. by Corinne Kostic, Simon Geoffrey Lillico, Sylvain Vincent Crippa, Nicolas Grandchamp, Héloïse Pilet, Stéphanie Philippe, Zen Lu, Tim James King, Jacques Mallet, Chamsy Sarkis, Yvan Arsenijevic, Christopher Bruce Alexander Whitelaw

“…Sixty percent of the piglets were transgenic, with mutant GUCY2D mRNA detected in the retina of all animals tested. Functional impairment of vision was observed among the transgenic pigs at 3 months of age, with a follow-up at 1 year indicating a subsequent slower progression of phenotype. …”
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Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes. by Ana Jovičić, Aaron D Gitler

“…The exosomal miRNA profiling dataset we have generated will provide a resource to aid in the investigation of this selection mechanism. …”
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Soil pollution and remediation: emerging challenges and innovations by Hao Chen, Bin Gao, Yuncong Li

“…These pollutants pose severe risks to environmental health and agricultural productivity by altering soil functionality and contaminant mobility. This perspective summarizes innovative monitoring and remediation technologies, including advanced sensors and bioremediation strategies, that enable real-time detection and effective management of soil pollutants. …”
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Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
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Adoption barriers and facilitators of wearable health devices with AI integration: a patient-centred perspective by Haitham Alzghaibi

“…The research emphasises the necessity of user education, technical reliability, and professional oversight for the successful integration of AI-powered wearables in the management of chronic diseases.…”
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Late Presentation of Acromioclavicular Joint Dislocation with Double Fracture of Coracoid Process Managed by Arthroscopic Stabilization Technique: A Case Report by Anand Kumaroth Somasundaram, Aiswarya Mohan, Anjali Appukuttan

“…The patient was successfully treated using an arthroscopically assisted stabilization technique with tendon graft augmentation and an arthroscopic repair of a superior labral tear, which was diagnosed intraoperatively. …”
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Socioeconomic Inequity in Access to Medical and Long-Term Care Among Older People by Shohei Okamoto, Atsuhiro Yamada, Erika Kobayashi, Jersey Liang

“…Conclusion Improving the understanding of available resources and strengthening the functions of health centres and communities are required to detect the needs of citizens and facilitate their access to necessary care.…”
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Research on lightweight weed recognition algorithm based on improved YOLOv8 by Zhang Chao, Liu Bin, Li Kun

“…Different scale features are used to improve the performance of target detection. Finally, the MPDIoU loss function is replaced to enhance the convergence and stability of the model. …”
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