A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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Comparative analysis of microwave indices for freeze/thaw state monitoring and adaptive thresholding implications by Zhicheng Yang, Tianjie Zhao, Qingfeng Wang, Lihua Peng, Youhua Ran, Yu Bai, Jingyao Zheng, Panpan Yao, Zhiqing Peng, Jinbiao Zhu, Xiaokang Kou, Yuei-An Liou, Jiancheng Shi

“…Near-surface soil freeze-thaw (F/T) cycles constitute a critical interface process regulating global hydrological dynamics, ecosystem succession, and climate feedback mechanisms. Leveraging its all-weather penetration capability, passive microwave remote sensing has emerged as a cornerstone for large-scale F/T state monitoring. …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep by XinKun Wang, Wei Li, QiaoYan Huang, HuiPing Sun, LeXiao Zhu, RuoHuai Gu, Feng Xing

“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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Multimodal Imaging of Brain Metastasis-Derived Extracellular Vesicles Using Superparamagnetic Iron Oxide Nanoparticle Labeling by Feginn Berle B, Juliussen S, Castilho Á, Solel E, Sdik Saed H, Vanderpoorten O, Lunavat TR, Thorsen F, Rigg E

“…Detection sensitivity was determined using agar phantoms, and in vivo tracking was validated through intramuscular injections in mice.Results: Uncoated 5 nm SPIONs demonstrated superior labeling efficiency, successfully marking over 90% of cells within 24 hours without significantly affecting cell growth. …”
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Parallel Jacobian Computation Based on Distance-2 Algorithm and Its Application in Coupling Problems by LIU Lixun, ZHANG Han, PENG Xinru, DOU Qinrong, WU Yingjie, GUO Jiong, LI Fu

“…In a word, this parallel coloring algorithm is successfully applied to the parallel Newton-Krylov method for solving the large-scale neutronic/thermal-hydraulics coupling problem.…”

Case Report: Post-operative mitral valve replacement complicating with a large cardiac mass and the role of TEE in Imaging [version 2; peer review: 2 approved] by Deepa Noronha, Chaithra Nayak, Syed Waleem Pasha, Padmanabh Kamath, Narasimha Pai D

“…The patient underwent successful mitral valve replacement as per ACC/AHA class I recommendation. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…Accurate and automated detection tools could enhance early diagnosis and intervention. …”
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Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media by Humaira Yasmin, Rawan Bossly, Fuad S. Alduais, Afrah Al-Bossly, Anwar Saeed

“…The analysis is done via the bvp4c MATLAB function in order to analyze the current model numerically by implementing convective boundary conditions. …”
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Additive Manufacturing for Automotive Radar Sensors Using Copper Inks and Pastes by Nihesh Mohan, Fabian Steinberger, Sonja Wächter, Hüseyin Erdogan, Gordon Elger

“…Radar sensors are critical for obstacle detection and navigation, especially for automated driving. …”
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Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy by Zhihe Chen, Zhongying Yang, Lifen Rao, Changgen Li, Na Zang, Enmei Liu

“…Conclusions HAdV-7 successfully infects pulmonary vascular endothelium and replicates effectively, causing injury to the endothelium, high VEGF expression and viral load in the serum, as well as ALI/ARDS. …”
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IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images by Zhaomin Yao, Weiming Xie, Jiaming Chen, Ying Zhan, Xiaodan Wu, Yingxin Dai, Yusong Pei, Zhiguo Wang, Guoxu Zhang

“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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Development of a two-layer 3D equine endometrial tissue model using genipin-crosslinked collagen scaffolds and 3D printing by Sawita Santiviparat, Setthibhak Suthithanakom, Sudchaya Bhanpattanakul, Sayamon Srisuwattanasagul, Kai Melde, Tom A. E. Stout, Theerawat Tharasanit

“…This model preserved the structural integrity necessary for glandular-like development and maintained the functional characteristics of equine endometrial tissue. …”
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Optimisation of bioaerosol sampling using an ultralight aircraft: A novel approach in determining the 3-D atmospheric biodiversity by Maria P. Plaza, Athanasios Charalampopoulos, Vivien Leier-Wirtz, Pia Viuf Ørby, Mathilde Kloster, Michael Dines Christiansen, Claudia Traidl-Hoffmann, Athanasios Damialis, Ulrich Gosewinkel

“…Moreover, biomonitoring campaigns often take place in urban environments, although sources can be located outside cities’ borders with ampler vegetation. …”
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Rapid flips between warm and cold extremes in a warming world by Sijia Wu, Ming Luo, Gabriel Ngar-Cheung Lau, Wei Zhang, Lin Wang, Zhen Liu, Lijie Lin, Yijing Wang, Erjia Ge, Jianfeng Li, Yuanchao Fan, Yimin Chen, Weilin Liao, Xiaoyu Wang, Xiaocong Xu, Zhixin Qi, Ziwei Huang, Faith Ka Shun Chan, David Yongqin Chen, Xiaoping Liu, Tao Pei

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Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

“…The target bacterial isolate was detected in medfly when inoculated with liquid diet regardless of age, but those fed a slurry-based diet and a separate water source had less establishment. …”
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Tailoring Atomic Ordering Uniformity Enables Selectively Leached Nanoporous Pd‐Ni‐P Metallic Glass for Enhanced Glucose Sensing by Yu Lou, Jian Li, Zhongzheng Yao, Zhenduo Wu, Huiqiang Ying, Lan Tan, Sinan Liu, Jianrong Zeng, Ruohan Yu, Hong Liu, Xun‐Li Wang, He Zhu, Si Lan

“…A microglucose sensor is successfully developed by integrating the nanoporous Pd‐Ni‐P MG with a screen‐printed electrode, demonstrating the practical applicability. …”
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TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery by Yubo Zhang, Zhibin Peng, Man Guo, Yangyang Wang, Jingsong Liu, Yishu Liu, Mi Li, Tianli Wei, Pengfei Li, Yingwei Zhao, Yansong Wang

“…Owing to the poor regenerative capabilities of endogenous oligodendrocyte precursor cells (OPCs) following SCI, there is a growing interest in alternative sources, such as human umbilical cord mesenchymal stem cells (HUCMSCs). …”
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Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation by Takuma Kaibara, Eiji Kondo, Masatake Matsuoka, Koji Iwasaki, Tomohiro Onodera, Daisuke Momma, Zen-Ichi Tanei, Shinya Tanaka, Norimasa Iwasaki

“…Postoperative follow-up demonstrated successful integration of the osteochondral graft and improved knee function scores over three years. …”
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The expression pattern of long non-coding RNA PVT1 in tumor tissues and in extracellular vesicles of colorectal cancer correlates with cancer progression by Kai Guo, Jie Yao, Qiang Yu, Zijian Li, Hu Huang, Jianguo Cheng, Zhigang Wang, Yunfeng Zhu

“…Here, we reported for the first time that PVT1 as a long non-coding RNA was successfully detected in extracellular vesicles excluded from SW620 and SW480 cells, and the expression level of PVT1 was higher in extracellular vesicles from the more aggressive cell SW620 than from SW480. …”
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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han

“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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