Suggested Topics within your search.
Suggested Topics within your search.
-
2921
WEB SERVICE OF WORKS PLANNING USING NETWORK GRAPH
Published 2022-05-01“…During the study, a set of theoretical, empirical, and modeling methods were applied, in particular: systematic analysis of scientific and methodological sources, the results of domestic and foreign experience on the problem, review of existing software to determine the problem solution state and select development tools of web service, analysis of methods and technologies network graphs construction, generalization of information on the problem. …”
Get full text
Article -
2922
Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema
Published 2024-01-01“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
Get full text
Article -
2923
Solar background radiation temperature calibration of a pure rotational Raman lidar
Published 2025-03-01“…It also allows a lidar not co-located with a routine external source to be continuously calibrated once an initial external calibration is done. …”
Get full text
Article -
2924
Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
Get full text
Article -
2925
-
2926
Optimal Coordinated Flood Control Scheduling of Three Gorges and Qingjiang Cascade Reservoirs
Published 2025-08-01Get full text
Article -
2927
Regulation of plant gene expression by tsRNAs in response to abiotic stress
Published 2025-05-01Get full text
Article -
2928
Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria
Published 2024-09-01“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
Get full text
Article -
2929
Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study
Published 2025-03-01“…Larger prospective, controlled trials are necessary to confirm these findings and to refine patient selection and technique optimization.…”
Get full text
Article -
2930
Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System
Published 2025-06-01“…We also obtained secondary data from local government sources in East Kalimantan. Data were processed using qualitative descriptive analysis, gender, and SWOT analysis. …”
Get full text
Article -
2931
Accumulation of long-chain unsaturated fatty acids in the airway inflammatory microenvironment drives eosinophil etosis and corticosteroid resistance
Published 2025-05-01“…Functional analyses were performed on purified eosinophils. …”
Get full text
Article -
2932
Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
Get full text
Article -
2933
Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area
Published 2025-03-01“…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
Get full text
Article -
2934
Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions
Published 2025-07-01“…Ultimately, a correct understanding of thermophysical processes in such structures will support the advancement of trends such as Lightweight Design, Functionally Graded Design, and Value Engineering in the development of curtain wall systems, through the optimized selection of façade configurations, accounting for temperature loads under specific climatic and design conditions.…”
Get full text
Article -
2935
Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g...
Published 2024-11-01“…To start, we used free computational tools and online bioinformatics resources, including predicting gene function using a multiple association network integration algorithm (geneMania), the Kyoto Encyclopedia of Genes and Genomes, the Annotation, Visualization and Integrated Discovery (DAVID) database and the stimulator of interferon genes. …”
Get full text
Article -
2936
Patient-reported outcome measures for fatigue in patients with chronic kidney disease: a systematic review
Published 2025-07-01“…The characteristics, dimensions of fatigue and psychometric properties of these measures were extracted and analysed.Data sources We searched MEDLINE, Embase, PsycINFO and CINAHL from database inception to February 2023.Eligibility criteria for selecting studies All studies that reported fatigue in patients with CKD stages 1–5 not receiving KRT.Results We identified 97 studies (20 (21%) randomised trials, 2 (2%) non-randomised trials and 75 (77%) observational studies). 27 different measures were used to assess fatigue, of which three were author-developed measures. …”
Get full text
Article -
2937
Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes
Published 2025-02-01“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
Get full text
Article -
2938
Editorial
Published 2025-05-01“…Notably, identifying Rhizopus sp. fungi as an alternative lactic acid source and the ozonation of vegetable oils underscore efforts toward environmentally friendly biochemical processes. …”
Get full text
Article -
2939
Assessment of EMF Exposure Induced by Wireless Cellular Phones in Various Usage Scenarios in France
Published 2025-01-01“…According to the type of sources, RF-EMF exposure can be categorized into uplink (device-to-base station) and downlink (base station-to-device) transmissions. …”
Get full text
Article -
2940
Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation
Published 2025-01-01“…BackgroundActive dietary flavonoids are a promising resource for novel drug discovery. Sweet potato, a widely cultivated functional crop, is abundant in flavonoids. …”
Get full text
Article